2021-01-29  Martin C. Frith  <Martin C. Frith>

	* doc/last-tutorial.txt:
	Small doc update
	[7911cdbc5e60] [tip]

2021-01-27  Martin C. Frith  <Martin C. Frith>

	* doc/Makefile, doc/last-evalues.txt, doc/last-papers.txt, doc/last-
	postmask.txt, doc/last-split.txt, doc/last-train.txt, doc/last-
	tuning.txt, doc/last-tutorial.txt, doc/last.txt, doc/lastal.txt:
	Big doc update
	[ba6a55ed7287]

2021-01-25  Martin C. Frith  <Martin C. Frith>

	* doc/lastal.txt, scripts/last-train, src/LastalArguments.cc:
	train --codon: more data & better pseudocounts
	[9a6365d5825a]

2021-01-14  Martin C. Frith  <Martin C. Frith>

	* src/Alignment.cc, src/lastal.cc, test/last-test.out, test/last-
	test.sh:
	Better repeat-masking for new-style frameshifts
	[e8001aa6f633]

2021-01-13  Martin C. Frith  <Martin C. Frith>

	* src/lastal.cc:
	Refactor
	[3713015a6ad3]

	* src/lastal.cc:
	Refactor
	[69de4393c89c]

	* doc/last-papers.txt, src/lastal.cc:
	Refactor
	[2ad10ab5b4b1]

2021-01-05  Martin C. Frith  <Martin C. Frith>

	* doc/last-train.txt, scripts/last-train:
	last-train: add codon & frameshift options!
	[977a35de8389]

	* scripts/last-train:
	Refactor
	[663475110c85]

2020-12-28  Martin C. Frith  <Martin C. Frith>

	* src/LastEvaluer.cc, src/mcf_frameshift_xdrop_aligner.cc,
	src/mcf_frameshift_xdrop_aligner.hh, test/last-test.out:
	Fix E-values for new-style frameshifts
	[a55b81199602]

2020-12-23  Martin C. Frith  <Martin C. Frith>

	* scripts/last-train, src/LastEvaluer.cc:
	Try to fix floating-point infinite loops
	[829c63f50494]

2020-12-15  Martin C. Frith  <Martin C. Frith>

	* src/Alignment.cc, src/lastal.cc, test/last-test.out, test/last-
	test.sh:
	New frameshifts: fix print precision of score
	[abed5cbf2f29]

2020-12-11  Martin C. Frith  <Martin C. Frith>

	* src/GeneticCode.cc, src/GeneticCode.hh, src/lastal.cc, test/last-
	test.out, test/last-test.sh:
	Better rep-masking for codons & new frameshifts
	[c1fbf7da4f68]

	* src/GappedXdropAlignerFrame.cc, src/GeneticCode.cc,
	src/GeneticCode.hh, src/lastal.cc:
	Refactor
	[f0ef1bb760a6]

2020-12-04  Martin C. Frith  <Martin C. Frith>

	* doc/last-train.txt, scripts/last-train:
	Add last-train --scale option
	[f8298e7154b0]

2020-12-03  Martin C. Frith  <Martin C. Frith>

	* scripts/last-train:
	Refactor
	[8d973000becc]

	* src/GappedXdropAligner.hh, src/GappedXdropAlignerFrame.cc:
	Refactor
	[f85ac4b37611]

	* src/mcf_frameshift_xdrop_aligner.cc:
	Change expected-count output for new frameshifts
	[6295d6a32b28]

	* src/Centroid.cc:
	Refactor
	[ee8f8ed3fd4e]

	* scripts/last-train:
	Refactor
	[e35d9df1d54c]

	* doc/lastdb.txt, src/Alphabet.cc, src/Alphabet.hh,
	src/LastdbArguments.cc, src/LastdbArguments.hh,
	src/MultiSequence.cc, src/MultiSequence.hh, src/lastdb.cc,
	src/mcf_substitution_matrix_stats.cc, test/last-test.out, test/last-
	test.sh:
	Add lastdb -q option
	[74ad9d8977ec]

2020-12-02  Martin C. Frith  <Martin C. Frith>

	* src/lastal.cc, test/last-test.out, test/last-test.sh:
	Protein-codon alignment: use tantan on the DNA
	[8ac7c496f9be]

	* src/Alignment.cc, src/Alignment.hh, src/AlignmentWrite.cc,
	src/LastEvaluer.cc, src/LastEvaluer.hh, src/lastal.cc, test/last-
	test.out, test/last-test.sh:
	E-values for new-style frameshifts!
	[fffb08324c7d]

2020-12-01  Martin C. Frith  <Martin C. Frith>

	* src/mcf_frameshift_xdrop_aligner.cc,
	src/mcf_frameshift_xdrop_aligner.hh:
	Start implementing frameshift E-value simulation
	[d73a654fdabb]

	* src/LastalArguments.cc, src/LastalArguments.hh, src/lastal.cc:
	Allow for non-integer alignment scores
	[4bc305f33933]

2020-11-30  Martin C. Frith  <Martin C. Frith>

	* src/LastEvaluer.cc, src/LastEvaluer.hh, src/lastal.cc:
	Refactor
	[f5a5aed6d38e]

	* src/AlignmentWrite.cc, src/LastEvaluer.cc, src/LastalArguments.cc:
	Refactor
	[49942e88c59e]

2020-11-27  Martin C. Frith  <Martin C. Frith>

	* src/AlignmentWrite.cc:
	Protein-codon alignment: fix writing X and *
	[922917aa2dd8]

2020-11-26  Martin C. Frith  <Martin C. Frith>

	* src/lastal.cc:
	Reduce lastal memory use, sometimes
	[bc682cb4f508]

	* src/LastEvaluer.cc, test/last-test.out:
	Fix minor bugs in E-value finite-size correction
	[8d49928d5e10]

	* src/LastEvaluer.cc, src/LastEvaluer.hh:
	Refactor
	[814e3863ab23]

	* scripts/last-train:
	Refactor
	[a1e4ab7fd745]

	* scripts/last-train:
	Refactor
	[70149e6fb67a]

2020-11-25  Martin C. Frith  <Martin C. Frith>

	* scripts/last-train, src/lastal.cc:
	Refactor
	[249167a86543]

2020-11-06  Martin C. Frith  <Martin C. Frith>

	* src/mcf_frameshift_xdrop_aligner.hh:
	Try to appease C++ compilers
	[62a147543f2b]

	* doc/last-split.txt:
	Add awk mismap trick to doc
	[aabc3e86c600]

	* src/GappedXdropAlignerFrame.cc:
	Refactor
	[10c6c0ff4ac2]

	* src/GappedXdropAligner.cc, src/GappedXdropAligner2qual.cc,
	src/GappedXdropAlignerDna.cc, src/GappedXdropAlignerFrame.cc,
	src/GappedXdropAlignerPssm.cc:
	Refactor
	[0bff03a84a63]

	* src/Alignment.cc, src/Alignment.hh, src/AlignmentWrite.cc,
	src/LastalArguments.cc, src/lastal.cc, src/makefile,
	src/mcf_frameshift_xdrop_aligner.cc,
	src/mcf_frameshift_xdrop_aligner.hh, test/last-test.out, test/last-
	test.sh:
	Add probabilities for new-style frameshifts
	[8b133765d82e]

2020-11-05  Martin C. Frith  <Martin C. Frith>

	* src/Alignment.hh, src/Centroid.cc, src/Centroid.hh:
	Refactor
	[8291399ebe14]

	* src/Alignment.hh, src/AlignmentWrite.cc, test/last-test.out, test
	/last-test.sh:
	Fix protein-codon alignment probabilities
	[86ac07a750ac]

2020-11-04  Martin C. Frith  <Martin C. Frith>

	* src/Centroid.cc, src/lastal.cc, src/mcf_gap_costs.cc,
	src/mcf_gap_costs.hh:
	Refactor
	[8383c3867429]

	* src/Alignment.cc, src/Alignment.hh, src/lastal.cc, src/makefile:
	Refactor
	[115ac5aa5bee]

	* src/Alignment.cc, src/AlignmentWrite.cc:
	Refactor
	[defdc3f2ccdd]

	* src/Alignment.cc:
	Refactor
	[7b420067c0fa]

	* src/Alignment.cc, src/Alignment.hh, src/AlignmentWrite.cc,
	src/Centroid.cc, src/Centroid.hh, src/lastal.cc:
	Refactor
	[60f728268532]

2020-10-14  Martin C. Frith  <Martin C. Frith>

	* scripts/last-dotplot:
	last-dotplot: fix crash on long annotation names
	[04663552433d]

	* scripts/last-dotplot:
	last-dotplot: fix crash on annotation names
	[2b38a62095d1]

	* src/Alignment.cc, src/LastalArguments.cc, src/LastalArguments.hh,
	src/lastal.cc, src/mcf_gap_costs.cc, src/mcf_gap_costs.hh, test
	/last-test.out, test/last-test.sh:
	Add new-style frameshifts (undocumented)
	[ef402c72783a]

2020-10-13  Martin C. Frith  <Martin C. Frith>

	* src/LastEvaluer.cc, src/LastEvaluer.hh, src/lastal.cc,
	test/badcodon.mat, test/last-test.out, test/last-test.sh:
	Fix E-values for protein-codon alignment
	[5cb92f44cc83]

2020-10-12  Martin C. Frith  <Martin C. Frith>

	* src/GappedXdropAligner.cc, src/GappedXdropAligner.hh,
	src/GappedXdropAligner2qual.cc, src/GappedXdropAlignerFrame.cc,
	src/GappedXdropAlignerInl.hh, src/GappedXdropAlignerPssm.cc,
	src/makefile, src/mcf_gap_costs.hh:
	Start adding new-style frameshifts
	[1724a2c77894]

	* src/Alignment.cc, src/Alignment.hh, src/lastal.cc,
	src/mcf_gap_costs.cc, src/mcf_gap_costs.hh:
	Refactor
	[9045041a2869]

2020-10-09  Martin C. Frith  <Martin C. Frith>

	* src/ScoreMatrix.cc, src/lastal.cc, src/makefile, test/BL62codon.mat,
	test/last-test.out, test/last-test.sh:
	Add protein-codon alignment (undocumented)!
	[f38f5833a8c5]

	* src/ScoreMatrix.cc:
	Almost add protein-codon alignment
	[58b948464438]

	* src/ScoreMatrix.cc:
	A bit more protein-codon alignment
	[1c51b31e980c]

	* src/ScoreMatrix.cc, src/ScoreMatrix.hh, src/lastal.cc:
	Further implement protein-codon alignment
	[aac2fdc8c1c6]

2020-10-08  Martin C. Frith  <Martin C. Frith>

	* src/ScoreMatrix.cc:
	Continue to implement protein-codon alignment
	[481c5c269f38]

2020-10-07  Martin C. Frith  <Martin C. Frith>

	* src/ScoreMatrix.cc:
	Even more protein-codon alignment...
	[454cc5a9912b]

	* src/ScoreMatrix.cc, src/ScoreMatrix.hh, src/lastal.cc:
	Yet more protein-codon alignment...
	[79ae30bc7f91]

	* src/Alignment.hh, src/AlignmentWrite.cc, src/lastal.cc:
	Further implement protein-codon alignment
	[ba2e7bf5361b]

	* src/Alignment.hh, src/AlignmentWrite.cc:
	Still implementing protein-codon alignment...
	[a9be6e20ff84]

	* src/AlignmentWrite.cc:
	More protein-codon alignment...
	[2aae6657858d]

	* src/AlignmentWrite.cc, src/SegmentPair.cc, src/SegmentPair.hh,
	src/lastal.cc, src/mcf_substitution_matrix_stats.cc,
	src/mcf_substitution_matrix_stats.hh:
	Further implement protein-codon alignment
	[5d4ebfa2a480]

2020-10-06  Martin C. Frith  <Martin C. Frith>

	* src/GeneticCode.cc, src/GeneticCode.hh:
	Continue implementing protein-codon alignment
	[7160752d7fd3]

	* src/CyclicSubsetSeed.cc, src/CyclicSubsetSeed.hh,
	src/SubsetSuffixArraySearch.cc:
	Start to implement protein-codon alignment
	[4c868f1f2d17]

2020-10-05  Martin C. Frith  <Martin C. Frith>

	* src/AlignmentWrite.cc, src/SubsetSuffixArraySearch.cc,
	src/lastal.cc:
	Refactor
	[ce1df9e364bd]

	* src/AlignmentWrite.cc:
	Refactor
	[e584e28846bb]

	* src/Alignment.hh, src/AlignmentWrite.cc, src/ScoreMatrix.cc,
	src/ScoreMatrix.hh, src/ScoreMatrixRow.hh:
	Refactor
	[a7e9f27fdc6a]

2020-09-23  Martin C. Frith  <Martin C. Frith>

	* data/RY8-7.seed, data/RY8-8.seed, test/last-test.out, test/last-
	test.sh:
	Improve RY8 seeding
	[300db7059c0c]

2020-09-15  Martin C. Frith  <Martin C. Frith>

	* src/dna_words_finder.cc, src/dna_words_finder.hh:
	Try to appease C++ compilers
	[367e48c99f55]

	* src/GappedXdropAligner.cc, src/GappedXdropAligner.hh,
	src/GappedXdropAligner2qual.cc, src/GappedXdropAligner3frame.cc,
	src/GappedXdropAligner3framePssm.cc, src/GappedXdropAlignerDna.cc,
	src/GappedXdropAlignerPssm.cc:
	Make lastal gapped alignment a bit faster
	[35ced3f550ea]

	* build/seed-doc.sh, build/seed-inc.sh, data/RY16-8.seed,
	data/RY32-10.seed, data/RY4-6.seed, data/RY8-7.seed, doc/Makefile,
	doc/last-tuning.txt, doc/last-tutorial.txt, src/CyclicSubsetSeed.cc,
	src/lastdb.cc, test/last-test.sh:
	Add & document more word-restricted seeds
	[bbb65995fa8b]

2020-09-10  Martin C. Frith  <Martin C. Frith>

	* doc/last-tuning.txt, doc/lastdb.txt, src/LastdbArguments.cc,
	src/LastdbArguments.hh, src/SubsetSuffixArray.cc,
	src/SubsetSuffixArray.hh, src/lastdb.cc, test/last-test.sh:
	lastdb: add -B, fix combining -s and -W
	[9d12eb4d3ec0]

2020-09-09  Martin C. Frith  <Martin C. Frith>

	* build/seed-doc.sh, data/RY4-6.seed, data/RY8-7.seed, doc/last-
	tuning.txt, doc/lastdb.txt, src/CyclicSubsetSeed.cc,
	src/CyclicSubsetSeed.hh, src/LastdbArguments.cc,
	src/LastdbArguments.hh, src/SubsetSuffixArray.cc, src/lastdb.cc,
	test/last-test.out, test/last-test.sh:
	Add word-restricted seeds!
	[6e176bb55817]

2020-09-08  Martin C. Frith  <Martin C. Frith>

	* src/CyclicSubsetSeed.cc:
	Refactor
	[d59f2b86632a]

2020-09-07  Martin C. Frith  <Martin C. Frith>

	* src/CyclicSubsetSeed.cc, src/CyclicSubsetSeed.hh,
	src/SubsetSuffixArray.cc, src/SubsetSuffixArray.hh, src/lastal.cc,
	src/lastdb.cc:
	Nearly finished adding word-restricted seeds...
	[bfdd9793c6bc]

	* src/dna_words_finder.cc, src/dna_words_finder.hh, src/lastdb.cc:
	Further adding word-restricted seeds...
	[d5dbecc57900]

	* src/lastal.cc:
	Refactor
	[c8665d2104b6]

	* src/lastal.cc, src/makefile:
	Still adding word-restricted seeds...
	[22d61e1146de]

	* src/lastal.cc:
	Refactor
	[7c0467ad29cd]

2020-09-04  Martin C. Frith  <Martin C. Frith>

	* src/lastdb.cc:
	Continue adding word-restricted seeds...
	[b4e211fcc354]

	* src/CyclicSubsetSeed.cc, src/CyclicSubsetSeed.hh, src/last.hh,
	src/lastdb.cc, src/makefile:
	Still adding word-restricted seeds...
	[4b25a1852823]

	* src/SubsetSuffixArray.cc, src/SubsetSuffixArray.hh,
	src/dna_words_finder.cc, src/dna_words_finder.hh, src/makefile:
	Adding word-restricted seeds...
	[3bfc47ec6666]

2020-09-03  Martin C. Frith  <Martin C. Frith>

	* src/CyclicSubsetSeed.cc, src/CyclicSubsetSeed.hh,
	src/SubsetSuffixArray.cc:
	Still implementing word-restricted seeds...
	[6e986b77e53e]

	* src/CyclicSubsetSeed.cc, src/CyclicSubsetSeed.hh,
	src/SubsetSuffixArray.cc, src/SubsetSuffixArray.hh,
	src/SubsetSuffixArraySort.cc, src/lastdb.cc:
	Continue implementing word-restricted seeds...
	[0b70ffe8bdfd]

	* src/SubsetSuffixArray.cc:
	Refactor
	[c3416a6d41e4]

	* src/SubsetSuffixArray.cc:
	Still implementing word-restricted seeds...
	[1a5f633d9b94]

2020-09-02  Martin C. Frith  <Martin C. Frith>

	* src/SubsetSuffixArray.cc, src/SubsetSuffixArray.hh,
	src/SubsetSuffixArraySearch.cc, src/lastal.cc:
	Further implementing word-restricted seeds...
	[05dc37d11175]

	* src/SubsetSuffixArray.cc, src/SubsetSuffixArray.hh:
	Continue implementing word-restricted seeds...
	[ab813d0b4051]

	* src/SubsetSuffixArray.cc, src/SubsetSuffixArray.hh, src/lastdb.cc:
	Continue implementing word-restricted seeds
	[4b9b2005ff34]

	* src/SubsetSuffixArray.hh, src/SubsetSuffixArraySort.cc,
	src/lastdb.cc:
	Continue to implement word-restricted seeds
	[a0e153f64147]

	* src/SubsetSuffixArray.cc, src/SubsetSuffixArray.hh,
	src/SubsetSuffixArraySearch.cc, src/SubsetSuffixArraySort.cc,
	src/lastal.cc, src/lastdb.cc:
	Start to implement word-restricted seeds
	[46de1fb360d9]

	* src/SubsetSuffixArray.cc, src/SubsetSuffixArray.hh,
	src/SubsetSuffixArraySearch.cc:
	Change lastdb bck for bucket depth = 0
	[ba2ffdcf37a8]

2020-09-01  Martin C. Frith  <Martin C. Frith>

	* src/mcf_zstream.hh:
	Tweak error message
	[094c1c64e34c]

	* src/SubsetSuffixArray.cc, src/SubsetSuffixArray.hh:
	Refactor
	[0d1d2fa2cd73]

	* src/SubsetSuffixArray.cc:
	Refactor
	[17950b1a912d]

	* src/CyclicSubsetSeed.cc, src/CyclicSubsetSeed.hh,
	src/SubsetSuffixArray.cc, src/SubsetSuffixArray.hh, src/lastal.cc:
	Fix never-gonna-happen integer overflows
	[b5bbc6604153]

	* src/CyclicSubsetSeed.cc, src/SubsetSuffixArray.cc, src/lastal.cc:
	Refactor
	[7f41f13cb9df]

2020-08-25  Martin C. Frith  <Martin C. Frith>

	* src/GappedXdropAlignerDna.cc:
	Fix "make depend"
	[a1997b0970f4]

2020-07-31  Martin C. Frith  <Martin C. Frith>

	* src/split/cbrc_split_aligner.cc, test/last-split-test.out, test
	/last-split-test.sh, test/spliceWithGap.maf:
	last-split: catch spliced-alignment math overflow
	[de7890c559b8]

	* scripts/last-dotplot:
	last-dotplot: fix bug in annotation names limit
	[5aaae537a930]

	* scripts/last-dotplot:
	last-dotplot: read BED-like files more robustly
	[579d74b5066f]

	* scripts/last-dotplot:
	last-dotplot: show annotation names!
	[5209deca661c]

	* scripts/last-dotplot:
	last-dotplot: implementing annotation names...
	[3b8d229f8359]

	* scripts/last-dotplot:
	last-dotplot: implementing annotation names...
	[70b0e512d696]

	* scripts/last-dotplot:
	last-dotplot: implementing annotation names...
	[170ab6c64728]

	* scripts/last-dotplot:
	last-dotplot: read annotations a bit faster
	[8ec299b42e28]

	* scripts/last-dotplot:
	last-dotplot: refactor
	[e43ecf1c3fb6]

2020-07-30  Martin C. Frith  <Martin C. Frith>

	* scripts/last-dotplot:
	last-dotplot: refactor
	[c5d3cf8c1058]

	* scripts/last-dotplot:
	last-dotplot: refactor
	[6cf9358f80da]

	* scripts/last-dotplot:
	last-dotplot: refactor
	[da8b081ec496]

	* scripts/last-dotplot:
	last-dotplot: refactor
	[a29f9cec16e1]

	* scripts/maf-convert:
	maf-convert: warn instead of crash on NaN
	[eb2abd424c87]

2020-06-11  Martin C. Frith  <Martin C. Frith>

	* doc/last-train.txt, scripts/last-train, src/lastal.cc:
	Make inconsistent last-train/lastal -Q an error
	[f2071b3c3173]

	* doc/last-train.txt, doc/lastal.txt, doc/lastdb.txt, scripts/last-
	train, src/LastalArguments.cc, src/LastdbArguments.cc,
	src/SequenceFormat.hh, src/last.hh, src/lastdb.cc,
	src/split/cbrc_split_aligner.cc, src/split/last-split.cc, test/last-
	test.out, test/last-test.sh:
	Add option to keep but ignore fastq quals
	[0315c96a5a9b]

2020-06-08  Martin C. Frith  <Martin C. Frith>

	* scripts/maf-convert:
	Fix small bug in maf-convert -J
	[cd67e8009c78]

	* doc/maf-convert.txt, scripts/maf-convert, test/maf-convert-test.out,
	test/maf-convert-test.sh:
	Add maf-convert -J option
	[bc7b2cdbcb32]

	* doc/maf-convert.txt, scripts/last-dotplot, scripts/last-train,
	scripts/maf-convert, scripts/maf-cut, test/maf-convert-test.out,
	test/maf-convert-test.sh:
	Add maf-convert to gff (with help from C. Plessy)
	[6d8d56a74b14]

2020-05-07  Martin C. Frith  <Martin C. Frith>

	* src/tantan.cc:
	Make tantan repeat-finding faster
	[543d36d39ce3]

2020-03-16  Martin C. Frith  <Martin C. Frith>

	* src/split/cbrc_split_aligner.cc, src/split/cbrc_split_aligner.hh:
	Reduce last-split memory & time usage a bit
	[ca3f417edc01]

	* src/split/cbrc_int_exponentiator.hh:
	Make last-split a bit faster
	[a380494ff77b]

	* src/split/cbrc_split_aligner.cc, src/split/cbrc_split_aligner.hh:
	Make last-split a bit faster
	[0b3571f8e14b]

2020-03-13  Martin C. Frith  <Martin C. Frith>

	* src/split/cbrc_split_aligner.cc:
	Refactor
	[ff73ca674104]

	* src/split/cbrc_split_aligner.cc, src/split/cbrc_split_aligner.hh:
	Make last-split much faster
	[6f4ec587fe25]

	* src/split/cbrc_split_aligner.cc, src/split/cbrc_split_aligner.hh:
	Refactor
	[3887935792ab]

2020-03-11  Martin C. Frith  <Martin C. Frith>

	* src/split/cbrc_split_aligner.cc:
	Make last-split a bit faster
	[8621c8e512ff]

	* src/split/cbrc_split_aligner.cc, src/split/cbrc_split_aligner.hh:
	Try to make last-split faster
	[13c4e8b892dc]

	* src/split/cbrc_split_aligner.cc, src/split/cbrc_split_aligner.hh,
	src/split/last-split.cc:
	Make last-split a bit faster
	[ba6739cb6e7b]

	* src/split/cbrc_split_aligner.cc, test/last-split-test.out:
	Tiny change to last-split probabilities
	[eb537293aa74]

	* src/split/cbrc_split_aligner.cc:
	Refactor
	[cf3b0bf3dac8]

	* src/split/cbrc_split_aligner.cc:
	Refactor
	[c0681ee6f1fd]

	* src/split/cbrc_split_aligner.cc:
	Refactor (rename a variable)
	[c62c2b618d94]

2020-01-20  Martin C. Frith  <Martin C. Frith>

	* scripts/last-postmask, test/last-postmask-test.out, test/last-
	postmask-test.sh:
	last-postmask: fix crash on length-1 DB name
	[1015a8df8312]

	* scripts/last-train:
	last-train: fix occasional crashes since v1020
	[b6a6f4a9d738]

2019-12-23  Martin C. Frith  <Martin C. Frith>

	* src/Alignment.cc, src/GappedXdropAligner.hh,
	src/GappedXdropAlignerDna.cc, src/mcf_simd.hh:
	Make it usable without SSE/SIMD
	[4270e27518ca]

2019-12-20  Martin C. Frith  <Martin C. Frith>

	* src/GappedXdropAligner.hh, src/GappedXdropAlignerDna.cc,
	src/mcf_simd.hh, test/last-test.out, test/last-test.sh:
	Maybe make lastal gapped alignment a bit faster
	[11810fcff80c]

2019-12-19  Martin C. Frith  <Martin C. Frith>

	* src/GappedXdropAligner.cc, src/GappedXdropAligner.hh,
	src/GappedXdropAlignerDna.cc, src/makefile,
	src/mcf_reverse_queue.hh, src/mcf_simd.hh:
	Maybe make lastal gapped alignment a bit faster
	[2be7c5f313a5]

2019-12-16  Martin C. Frith  <Martin C. Frith>

	* src/Alignment.cc, src/GappedXdropAligner.hh,
	src/GappedXdropAlignerDna.cc, src/mcf_simd.hh:
	Make lastal DNA gapped alignment faster
	[daa684e4956e]

	* src/Alignment.cc, src/GappedXdropAligner.hh,
	src/GappedXdropAlignerDna.cc, src/ScoreMatrixRow.hh,
	src/mcf_simd.hh:
	Make lastal DNA gapped alignment faster
	[7fdb95aea8e3]

	* src/Alignment.cc, src/Alignment.hh, src/GappedXdropAlignerDna.cc,
	src/lastal.cc, src/mcf_simd.hh:
	Refactor
	[b1fc3a37fe34]

2019-12-12  Martin C. Frith  <Martin C. Frith>

	* src/Alignment.cc, src/GappedXdropAligner.cc,
	src/GappedXdropAligner.hh, src/GappedXdropAlignerDna.cc,
	src/GappedXdropAlignerPssm.cc, src/makefile, src/mcf_simd.hh, test
	/last-test.out, test/last-test.sh:
	Make lastal DNA gapped alignment faster
	[a02f4aab6116]

	* src/GappedXdropAligner.cc, src/GappedXdropAlignerPssm.cc,
	src/mcf_simd.hh:
	Refactor
	[d21b748f5540]

	* src/GappedXdropAligner.cc, src/GappedXdropAligner.hh,
	src/GappedXdropAlignerPssm.cc:
	Refactor
	[84db4d2edb22]

	* src/GappedXdropAligner.cc, src/GappedXdropAligner2qual.cc,
	src/GappedXdropAlignerInl.hh, src/GappedXdropAlignerPssm.cc:
	Refactor
	[759bd401fd1b]

2019-12-11  Martin C. Frith  <Martin C. Frith>

	* src/GappedXdropAligner.cc, src/GappedXdropAligner2qual.cc,
	src/GappedXdropAlignerPssm.cc, test/last-train-test.out:
	Change lastal probabilities slightly
	[1cd65b7f8fdb]

	* src/GappedXdropAligner2qual.cc:
	Refactor
	[f888698950e8]

	* src/GappedXdropAligner.cc, src/GappedXdropAligner2qual.cc,
	src/GappedXdropAligner3frame.cc,
	src/GappedXdropAligner3framePssm.cc, src/GappedXdropAlignerInl.hh,
	src/GappedXdropAlignerPssm.cc:
	Refactor & robustify the code
	[6ee595437d4c]

	* src/Alignment.cc, src/GappedXdropAligner.cc,
	src/GappedXdropAligner.hh, src/GappedXdropAligner2qual.cc,
	src/GappedXdropAlignerInl.hh, src/GappedXdropAlignerPssm.cc,
	src/mcf_gap_costs.cc, src/mcf_gap_costs.hh:
	Refactor
	[14a1fdd74624]

2019-12-10  Martin C. Frith  <Martin C. Frith>

	* src/GappedXdropAligner.cc, src/GappedXdropAlignerPssm.cc,
	src/alp/njn_matrix.hpp, src/alp/njn_random.cpp,
	src/alp/njn_vector.hpp, src/makefile, src/mcf_simd.hh:
	Robustify compilation
	[5b00a436e53c]

2019-12-09  Martin C. Frith  <Martin C. Frith>

	* src/GappedXdropAligner.cc, src/GappedXdropAligner.hh,
	src/GappedXdropAlignerPssm.cc, src/mcf_simd.hh:
	Refactor
	[e0434cbfa780]

	* src/GappedXdropAligner.cc, src/GappedXdropAligner.hh,
	src/GappedXdropAligner2qual.cc, src/GappedXdropAligner3frame.cc,
	src/GappedXdropAligner3framePssm.cc, src/GappedXdropAlignerPssm.cc:
	Refactor
	[29b88752b6d6]

	* makefile, src/makefile:
	Fix compile error (thanks: V Brendel & D Eccles)
	[cf7b477fbeaf]

	* src/GappedXdropAligner.cc, src/GappedXdropAlignerPssm.cc,
	src/mcf_contiguous_queue.hh:
	Refactor
	[4b2847c49990]

	* src/GappedXdropAligner.cc, src/GappedXdropAlignerPssm.cc:
	Refactor
	[8410315ff484]

	* src/GappedXdropAligner.cc, src/GappedXdropAligner2qual.cc,
	src/GappedXdropAlignerPssm.cc:
	Refactor
	[c614e7fba41c]

	* src/GappedXdropAligner.cc, src/GappedXdropAligner2qual.cc,
	src/GappedXdropAlignerPssm.cc:
	Refactor
	[ede8e6df999a]

	* src/GappedXdropAligner.cc, src/GappedXdropAlignerPssm.cc,
	src/mcf_contiguous_queue.hh:
	Refactor
	[aa391569f221]

	* examples/multiMito.maf, src/GappedXdropAligner.cc,
	src/GappedXdropAligner2qual.cc, src/GappedXdropAlignerInl.hh,
	src/GappedXdropAlignerPssm.cc, test/last-test.out, test/last-train-
	test.out, test/maf-swap-test.out:
	Change lastal probabilities slightly
	[c24e24e0c606]

2019-11-28  Martin C. Frith  <Martin C. Frith>

	* doc/last-train.txt, scripts/last-train, test/last-train-test.out:
	train: double scale if integer-rounding is bad
	[887c0e6339d1]

2019-11-27  Martin C. Frith  <Martin C. Frith>

	* scripts/last-train, test/last-train-test.out:
	!Make last-train use balanced length probability
	[fff603c39404]

	* scripts/last-train, test/last-train-test.out:
	train: change integer-rounding of gap open costs
	[d4e0fcd8cc2b]

2019-11-26  Martin C. Frith  <Martin C. Frith>

	* src/LastalArguments.cc, src/lastal.cc, test/last-test.out:
	!Change lastal default gapless score threshold
	[24e288b4947c]

	* scripts/last-train:
	Refactor
	[4a486c301cd5]

	* scripts/last-train:
	Refactor
	[932a5e822d1c]

2019-11-21  Martin C. Frith  <Martin C. Frith>

	* scripts/last-train:
	Refactor
	[037daaa2fe00]

	* scripts/last-train:
	Refactor
	[ad8ed4200d8c]

	* scripts/last-train:
	Refactor
	[87e4bbb5b03f]

2019-11-18  Martin C. Frith  <Martin C. Frith>

	* src/GappedXdropAligner.cc, src/GappedXdropAligner.hh,
	src/GappedXdropAligner2qual.cc, src/GappedXdropAligner3frame.cc,
	src/GappedXdropAligner3framePssm.cc, src/GappedXdropAlignerInl.hh,
	src/GappedXdropAlignerPssm.cc, src/mcf_simd.hh:
	Refactor
	[f0bc43d74861]

	* src/GappedXdropAligner.cc, src/GappedXdropAlignerInl.hh,
	src/GappedXdropAlignerPssm.cc, src/ScoreMatrix.cc,
	src/ScoreMatrix.hh, src/mcf_simd.hh:
	Refactor
	[f164ba36017b]

	* scripts/last-train, src/Alignment.cc, src/Centroid.cc,
	src/Centroid.hh, src/GappedXdropAligner.cc,
	src/GappedXdropAligner.hh, test/last-test.out:
	Remove always-zero counts from lastal -j7
	[43344af70eab]

2019-11-15  Martin C. Frith  <Martin C. Frith>

	* src/Centroid.cc:
	Re-order some probability calculations
	[f46e1c98977c]

	* doc/lastal.txt, examples/multiMito.maf, scripts/last-train,
	src/Alignment.cc, src/Centroid.cc, src/Centroid.hh, test/last-
	test.out, test/last-train-test.out, test/maf-swap-test.out:
	!Get lastal probabilities from "model A"
	[033e6b4b0308]

	* src/Centroid.cc:
	Re-order probability calculations
	[b97eb8aee1f7]

2019-11-14  Martin C. Frith  <Martin C. Frith>

	* src/Centroid.cc:
	Refactor (better variable names)
	[54db8ec6938c]

	* doc/lastal.txt, src/Alignment.cc, src/Centroid.cc, src/Centroid.hh,
	src/LastalArguments.cc:
	Remove probabilities for generalized affine gaps
	[2e10e14cc66d]

2019-11-12  Martin C. Frith  <Martin C. Frith>

	* src/GappedXdropAlignerPssm.cc:
	Make fastq gapped alignment faster (SIMD)!
	[6afae8dec8f0]

	* src/GappedXdropAlignerPssm.cc:
	Refactor
	[168d611f79ab]

	* src/GappedXdropAlignerPssm.cc, test/last-test.out, test/last-
	test.sh:
	Refactor
	[bdc3abede08a]

	* makefile, src/Centroid.cc, src/GappedXdropAligner.cc,
	src/GappedXdropAligner.hh, src/GappedXdropAligner2qual.cc,
	src/GappedXdropAlignerPssm.cc, src/makefile, src/mcf_simd.hh:
	Make fasta gapped alignment faster (SIMD)!
	[2a74b539aecf]

2019-11-11  Martin C. Frith  <Martin C. Frith>

	* src/GappedXdropAligner.cc:
	Refactor
	[92f84eaa2c77]

	* src/Centroid.cc, src/Centroid.hh, src/GappedXdropAligner.cc,
	src/GappedXdropAligner.hh, src/makefile,
	src/mcf_contiguous_queue.hh:
	Refactor (not sure if useful)
	[f1192efe0bec]

	* src/Alignment.cc, src/GappedXdropAligner.cc,
	src/GappedXdropAligner.hh, src/GappedXdropAligner2qual.cc,
	src/GappedXdropAlignerPssm.cc, src/GreedyXdropAligner.cc,
	src/GreedyXdropAligner.hh:
	Refactor
	[de3177d4a626]

	* src/GappedXdropAligner.cc, src/GappedXdropAligner.hh,
	src/GappedXdropAligner2qual.cc, src/GappedXdropAligner3frame.cc,
	src/GappedXdropAligner3framePssm.cc, src/GappedXdropAlignerPssm.cc:
	Refactor
	[b726e939f94c]

	* src/GappedXdropAligner.cc, src/GappedXdropAligner.hh,
	src/GappedXdropAligner2qual.cc, src/GappedXdropAlignerPssm.cc:
	Refactor
	[1587261f2469]

	* src/Centroid.hh, src/GappedXdropAligner.cc,
	src/GappedXdropAligner.hh, src/GappedXdropAligner2qual.cc,
	src/GappedXdropAligner3frame.cc,
	src/GappedXdropAligner3framePssm.cc, src/GappedXdropAlignerInl.hh,
	src/GappedXdropAlignerPssm.cc:
	Refactor (std::size_t -> size_t)
	[0cdc7da1019d]

	* src/Centroid.cc, src/Centroid.hh, src/GappedXdropAligner.cc,
	src/GappedXdropAligner.hh, src/GappedXdropAligner3frame.cc,
	src/alp/njn_random.cpp, src/makefile:
	Make lastal gapped alignment a bit faster
	[5506d2756b47]

	* src/LastEvaluer.hh, test/last-test.out, test/last-test.sh:
	Fix lastal crash on empty lastdb database
	[e5c59d1ed3a6]

2019-10-09  Martin C. Frith  <Martin C. Frith>

	* data/BL80.mat, data/PAM10.mat, data/PAM30.mat:
	Add PAM10 substitution score matrix
	[e57e547b8235]

2019-10-08  Martin C. Frith  <Martin C. Frith>

	* src/lastal.cc, src/lastdb.cc:
	Omit non-alphabet letters for DB seq lengths
	[7f841cc97f20]

	* src/SubsetMinimizerFinder.cc, src/SubsetMinimizerFinder.hh,
	src/SubsetSuffixArray.cc, src/lastal.cc:
	Refactor
	[4011a21f96ad]

2019-10-07  Martin C. Frith  <Martin C. Frith>

	* src/ScoreMatrix.cc, src/ScoreMatrix.hh, src/lastal.cc,
	src/mcf_substitution_matrix_stats.cc,
	src/mcf_substitution_matrix_stats.hh:
	Allow score matrix with letter frequencies
	[50bcc51ca59b]

	* src/CyclicSubsetSeed.hh, src/ScoreMatrix.cc, src/ScoreMatrix.hh,
	src/ScoreMatrixRow.hh, src/makefile:
	Refactor
	[ca6613dd1f06]

	* src/LastEvaluer.cc, src/LastEvaluer.hh, src/lastal.cc:
	Enable stored E-value params for any genetic code
	[f757e6ca4edb]

	* build/gc-inc.sh, data/gc.prt, doc/lastal.txt, src/GeneticCode.cc,
	src/GeneticCode.hh, src/LastalArguments.cc, src/lastal.cc,
	src/makefile, test/last-test.out, test/last-test.sh:
	Add NCBI genetic codes
	[88adecc284af]

	* doc/last-evalues.txt, src/LastEvaluer.cc, src/LastEvaluer.hh,
	src/LastalArguments.cc, src/LastalArguments.hh, src/lastal.cc,
	src/lastdb.cc, test/last-test.out:
	Improve E-values for multiple short DB sequences
	[49caf55d4d4d]

2019-08-21  Martin C. Frith  <Martin C. Frith>

	* doc/last-dotplot.txt, scripts/last-dotplot:
	dotplot: change satellite-repeat color to purple
	[fb43f850eba2]

2019-07-16  Martin C. Frith  <Martin C. Frith>

	* doc/last-split.txt, doc/last-tutorial.txt, scripts/last-train,
	src/split/last-split-main.cc, test/last-split-test.out, test/last-
	split-test.sh:
	Change last-split -m default to 1
	[2a722dbe737a]

2019-06-27  Martin C. Frith  <Martin C. Frith>

	* src/split/last-split.cc:
	Fix rare last-split spliced alignment crash
	[4f77b3fc0720]

2019-06-21  Martin C. Frith  <Martin C. Frith>

	* scripts/last-dotplot:
	dotplot: change the undocumented input format
	[0e184d90d5da]

2019-04-22  Martin C. Frith  <Martin C. Frith>

	* doc/last-dotplot.txt, scripts/last-dotplot:
	Add last-dotplot --join option
	[27c26371226b]

2019-04-01  Martin C. Frith  <Martin C. Frith>

	* src/LambdaCalculator.cc, src/LambdaCalculator.hh,
	src/TantanMasker.cc, src/lastal.cc, src/makefile,
	src/mcf_substitution_matrix_stats.cc,
	src/mcf_substitution_matrix_stats.hh:
	Make lastal startup even faster
	[9b416e560dc3]

	* src/LambdaCalculator.cc, src/LambdaCalculator.hh, src/makefile:
	Make lastal startup faster
	[d429589d040e]

	* src/Alignment.cc, src/Centroid.cc, src/Centroid.hh:
	Simplify some probability calculations a bit
	[9eeaeea88f2c]

2019-03-29  Martin C. Frith  <Martin C. Frith>

	* src/Alignment.cc, src/Centroid.cc, src/Centroid.hh:
	Refactor
	[f3f69ccff967]

2019-03-28  Martin C. Frith  <Martin C. Frith>

	* src/Alignment.cc, src/Alignment.hh, src/Centroid.cc,
	src/Centroid.hh, src/GeneralizedAffineGapCosts.cc,
	src/GeneralizedAffineGapCosts.hh, src/LastalArguments.cc,
	src/LastalArguments.hh, src/lastal.cc, src/makefile,
	src/mcf_gap_costs.cc, src/mcf_gap_costs.hh:
	Add piecewise linear gap costs (unfinished)
	[3701b1e2019b]

	* doc/last-train.txt, doc/lastal.txt, scripts/last-train,
	src/LastalArguments.cc, src/LastalArguments.hh, src/ScoreMatrix.cc,
	src/ScoreMatrix.hh, src/lastal.cc, test/dfam3-LTR22B1.fa,
	test/dfam3-LTR22C.fa, test/last-test.out, test/last-test.sh:
	Add lastal/last-train -X option for ambiguous N/X
	[2b0e54aee679]

2019-02-27  Martin C. Frith  <Martin C. Frith>

	* src/lastal.cc:
	Refactor
	[1ed9db7f46ca]

	* src/lastal.cc:
	Refactor
	[ae880ec00591]

2019-02-26  Martin C. Frith  <Martin C. Frith>

	* src/lastal.cc:
	Refactor
	[6189dce68b46]

	* doc/lastal.txt, src/LastalArguments.cc, src/lastal.cc, src/makefile,
	src/split/cbrc_split_aligner.cc:
	Change the effect of setting lastal option -t
	[2073177a7920]

	* src/lastal.cc, test/last-train-test.out:
	Fix fastq-aware last-train (lastal -j7)
	[7dcde7432ed7]

2019-02-25  Martin C. Frith  <Martin C. Frith>

	* src/OneQualityScoreMatrix.cc, src/OneQualityScoreMatrix.hh,
	src/TwoQualityScoreMatrix.cc, src/TwoQualityScoreMatrix.hh,
	src/lastal.cc, src/qualityScoreUtil.hh:
	Refactor
	[1bbe50060a6f]

	* src/lastal.cc, src/mcf_substitution_matrix_stats.cc,
	src/mcf_substitution_matrix_stats.hh:
	Make lastal code more robust for non-DNA
	[a75e610c943c]

	* src/lastal.cc, src/makefile, src/mcf_substitution_matrix_stats.cc,
	src/mcf_substitution_matrix_stats.hh:
	Refactor (prepare new score-matrix analysis)
	[685f6de69cc8]

	* src/LambdaCalculator.cc, src/LambdaCalculator.hh,
	src/TantanMasker.cc, src/lastal.cc:
	Refactor
	[92c7b8f19291]

	* scripts/last-train, src/LastEvaluer.hh, src/LastalArguments.cc,
	src/LastalArguments.hh, src/cbrc_linalg.cc, src/cbrc_linalg.hh,
	src/lastal.cc, src/makefile, src/split/cbrc_linalg.cc,
	src/split/cbrc_linalg.hh:
	Refactor
	[a5c1e7e987ff]

2018-12-26  Martin C. Frith  <Martin C. Frith>

	* src/tantan.cc:
	Make tantan repeat-finding faster
	[44199bff9cef]

	* doc/Makefile, doc/last-parallel.txt, doc/last-split.txt, doc/last-
	tutorial.txt:
	Update the documents a bit
	[6727ae8b7a12]

2018-12-10  Martin C. Frith  <Martin C. Frith>

	* doc/last-dotplot.txt, scripts/last-dotplot:
	Add last-dotplot --maxseqs option
	[ed0fb9b1eb40]

	* src/split/last-split.cc:
	Make last-split -n keep E-values
	[2063a5a7d7ac]

2018-10-30  Martin C. Frith  <Martin C. Frith>

	* doc/last-train.txt, doc/lastal.txt, doc/lastdb.txt, scripts/last-
	train, src/LastalArguments.cc, src/LastdbArguments.cc,
	src/MultiSequence.hh, src/MultiSequenceQual.cc,
	src/SequenceFormat.hh, src/last.hh, test/last-test.out, test/last-
	test.sh:
	Add fastq-ignore option
	[c551d04a3928]

2018-10-29  Martin C. Frith  <Martin C. Frith>

	* src/LastalArguments.cc, src/SequenceFormat.hh,
	src/SubsetSuffixArray.cc, src/lastal.cc, src/lastdb.cc:
	Refactor
	[96b45da7bf0f]

	* scripts/last-dotplot, scripts/last-map-probs, scripts/last-postmask,
	scripts/last-train, scripts/maf-convert, scripts/maf-cut, scripts
	/maf-swap:
	Fix gz reading for Python3
	[c54672c8892e]

2018-09-10  Martin C. Frith  <Martin C. Frith>

	* scripts/last-map-probs:
	Python3-ify last-map-probs
	[83191e47259e]

2018-09-07  Martin C. Frith  <Martin C. Frith>

	* src/last-pair-probs.cc:
	Make pair-probs almost work for ref rev strands
	[da8c69023d0a]

	* scripts/last-postmask:
	postmask: fix asymmetric matrix & ref rev strand
	[d4ecf378f967]

2018-09-05  Martin C. Frith  <Martin C. Frith>

	* doc/last-papers.txt, doc/last-train.txt, doc/lastal.txt,
	doc/lastdb.txt:
	Improve the documentation
	[ffb4e02e04b0]

	* scripts/fastq-interleave:
	fastq-interleave: add /1 & /2 to identical names
	[dd61bce162f0]

	* doc/last-train.txt, scripts/last-train, test/last-train-test.out,
	test/last-train-test.sh:
	last-train: train substitutions from fastq!
	[6de96c2afe47]

2018-08-29  Martin C. Frith  <Martin C. Frith>

	* src/lastal.cc:
	Fix lastal -j7 quality-aware expected counts
	[f70bcd86eb83]

2018-08-24  Martin C. Frith  <Martin C. Frith>

	* src/MultiSequence.cc, src/MultiSequence.hh,
	src/MultiSequenceQual.cc, src/last.hh:
	Read fastq faster
	[41800ed89eb8]

2018-08-21  Martin C. Frith  <Martin C. Frith>

	* src/Alignment.cc, src/Centroid.cc, src/Centroid.hh, src/lastal.cc:
	lastal -j7: quality-aware expected counts
	[9e0b0d0c8438]

2018-08-20  Martin C. Frith  <Martin C. Frith>

	* src/Centroid.cc, src/QualityPssmMaker.cc, src/QualityPssmMaker.hh,
	src/lastal.cc:
	Refactor
	[e454003e6a8a]

2018-08-01  Martin C. Frith  <Martin C. Frith>

	* doc/last-split.txt, src/split/last-split-main.cc, src/split/last-
	split.cc, src/split/last-split.hh, test/last-split-test.out, test
	/last-split-test.sh:
	Add last-split --format option
	[db2bd938c9b8]

2018-07-30  Martin C. Frith  <Martin C. Frith>

	* scripts/last-postmask:
	postmask: fix bug for spliced alignments
	[e7da3afc2179]

2018-07-17  Martin C. Frith  <Martin C. Frith>

	* scripts/maf-join:
	Python3-ify maf-join
	[764713f076f0]

	* src/lastal.cc, test/last-test.out, test/last-test.sh:
	Fix crash for bad score matrix
	[318e420407d8]

2018-06-25  Martin C. Frith  <Martin C. Frith>

	* scripts/last-dotplot:
	Make last-dotplot really work with Python3
	[82b69208c878]

2018-05-28  Martin C. Frith  <Martin C. Frith>

	* scripts/last-dotplot, scripts/last-train, scripts/maf-convert,
	scripts/maf-swap, test/last-test.sh, test/maf-swap-test.out, test
	/maf-swap-test.sh:
	Python3-ify: dotplot, train, convert, swap
	[f3f1ec72542f]

	* scripts/last-train, test/last-train-test.out:
	Purely cosmetic change to last-train output
	[05d2563d02e0]

	* scripts/last-postmask, test/102.maf, test/last-postmask-test.out,
	test/last-split-test.out:
	Fix postmask header bug introduced in v938
	[76cdd2203460]

2018-05-14  Martin C. Frith  <Martin C. Frith>

	* scripts/last-dotplot, scripts/last-postmask, test/102.maf, test
	/last-postmask-test.out, test/last-postmask-test.sh, test/last-
	split-test.out, test/last-split-test.sh:
	postmask: fix bug for unusual alignment headers
	[65969d4d464d]

	* scripts/last-dotplot, scripts/last-map-probs, scripts/last-postmask,
	scripts/last-train, scripts/maf-convert, scripts/maf-swap:
	Make last-train find LAST programs more robustly
	[8a4fadbe6080]

2018-05-07  Martin C. Frith  <Martin C. Frith>

	* scripts/last-postmask, scripts/last-train, scripts/maf-convert,
	scripts/maf-join, scripts/maf-swap:
	Modernize the Python code
	[b1c09fdd12fe]

	* doc/last-tuning.txt, doc/lastal.txt, doc/lastdb.txt,
	src/LastalArguments.cc, src/LastalArguments.hh, test/last-test.out,
	test/last-test.sh:
	Change lastal -x & -z options
	[b09d82479c91]

	* doc/last-train.txt, scripts/last-train:
	Make last-train use last-postmask
	[2755c8f0dc79]

	* scripts/last-postmask, test/last-postmask-test.out:
	postmask: bugfix for strand-asymmetric scores
	[9caca45429d8]

2018-04-20  Martin C. Frith  <Martin C. Frith>

	* doc/Makefile, doc/lastal.txt, doc/maf-cut.txt, scripts/maf-cut:
	Add maf-cut utility
	[482845444bcd]

2018-04-18  Martin C. Frith  <Martin C. Frith>

	* src/ScoreMatrix.cc, src/ScoreMatrix.hh, src/lastal.cc, src/makefile,
	test/last-test.out:
	Use appropriate scores for ambiguous DNA letters
	[75785542d5a0]

2018-04-17  Martin C. Frith  <Martin C. Frith>

	* src/ScoreMatrix.cc, src/ScoreMatrix.hh, test/last-test.out:
	Prettify the score matrix in lastal's header
	[68bd00d2faff]

	* src/ScoreMatrix.cc, src/lastal.cc:
	Refactor
	[d1aa91889332]

	* src/ScoreMatrix.cc, src/ScoreMatrix.hh, src/TantanMasker.cc,
	src/lastal.cc:
	Refactor
	[e22cac29168c]

2018-04-16  Martin C. Frith  <Martin C. Frith>

	* src/QualityPssmMaker.cc, src/ScoreMatrix.cc, src/ScoreMatrix.hh,
	src/qualityScoreUtil.hh:
	Refactor
	[fb851b8892a5]

2018-03-05  Martin C. Frith  <Martin C. Frith>

	* scripts/last-dotplot, test/last-dotplot-test.out, test/last-dotplot-
	test.sh:
	Fix dotplot --strands bug with cut sequences
	[bc08832db1a1]

	* scripts/last-dotplot, test/last-dotplot-test.out, test/last-dotplot-
	test.sh:
	Fix dotplot crash for sorting by sequence length
	[e1861f956f60]

2018-02-26  Martin C. Frith  <Martin C. Frith>

	* doc/lastdb.txt, src/Alphabet.cc, test/last-test.out, test/last-
	test.sh:
	Convert Us in RNA to Ts
	[e7d7cb7db0a7]

2018-02-13  Martin C. Frith  <Martin C. Frith>

	* doc/lastdb.txt, src/SubsetSuffixArray.hh,
	src/SubsetSuffixArraySort.cc, src/lastdb.cc:
	Multi-thread lastdb's main sort
	[77d8757028c2]

	* src/alp/sls_alignment_evaluer.cpp, test/last-test.out:
	Fix some E-value & last-train fails
	[2c57015b1e89]

2018-01-05  Martin C. Frith  <Martin C. Frith>

	* src/Alignment.cc, src/Alignment.hh, src/Centroid.cc,
	src/Centroid.hh:
	Refactor
	[8430dbf5abe7]

	* src/Centroid.cc:
	Try to calculate lastal probs a tiny bit faster
	[1abf5130f283]

	* src/Alignment.cc, src/Alignment.hh, src/AlignmentWrite.cc,
	src/Centroid.cc, src/Centroid.hh:
	Refactor
	[57012f1307c8]

	* src/Alignment.cc, src/Centroid.cc, src/Centroid.hh:
	Refactor
	[c98504d1610e]

	* src/Centroid.cc, src/Centroid.hh:
	Refactor
	[c83131b68177]

2017-12-21  Martin C. Frith  <Martin C. Frith>

	* doc/last-dotplot.txt, scripts/last-dotplot:
	last-dotplot: add strand/orientation options
	[ffe68ba3d865]

	* scripts/last-dotplot:
	Refactor last-dotplot
	[6079fabb49a5]

2017-12-05  Martin C. Frith  <Martin C. Frith>

	* doc/last-dotplot.txt, scripts/last-dotplot:
	last-dotplot: add alignment-order options
	[f4ca19d126e3]

	* scripts/last-dotplot:
	Refactor last-dotplot
	[e87abc7ae9c6]

2017-11-08  Martin C. Frith  <Martin C. Frith>

	* scripts/last-dotplot:
	Tweak last-dotplot range-end pixels
	[8834139fa8a8]

	* doc/last-dotplot.txt, scripts/last-dotplot:
	Add last-dotplot secondary alignments option
	[4080f3f6f73d]

	* scripts/last-dotplot:
	Add gap-cutting options to last-dotplot
	[42653029d900]

	* doc/last-dotplot.txt, scripts/last-dotplot:
	Remove last-dotplot trim options
	[92dfad507286]

	* scripts/last-dotplot:
	Refactor last-dotplot
	[6840398323e1]

	* scripts/last-dotplot:
	Tweak last-dotplot's sort options
	[87991b57ed04]

	* scripts/last-dotplot:
	Refactor last-dotplot
	[21fbf377641f]

	* scripts/last-dotplot:
	Refactor last-dotplot
	[8d52cef22afa]

	* scripts/last-dotplot:
	Tweak dotplot labels
	[c2f50cd4e29d]

	* doc/last-dotplot.txt, scripts/last-dotplot:
	Make last-dotplot try to find a nice font
	[3af6b02e3f9c]

	* src/CyclicSubsetSeed.cc, src/ScoreMatrix.cc, src/io.cc, src/io.hh,
	src/last-pair-probs.cc, src/lastal.cc, src/lastdb.cc, src/makefile,
	src/zio.hh:
	Try to fix build fails on some computers
	[db84a7e4ff8a]

2017-11-02  Martin C. Frith  <Martin C. Frith>

	* scripts/last-dotplot:
	Tweak last-dotplot's label placement
	[2003b209d750]

	* scripts/last-dotplot:
	Refactor last-dotplot
	[5ce3e786e05a]

	* scripts/last-dotplot:
	Refactor last-dotplot
	[ccf8902bf86c]

	* doc/last-dotplot.txt, scripts/last-dotplot:
	Change last-dotplot's label options
	[f6a9c15287ea]

	* scripts/last-dotplot:
	Refactor last-dotplot
	[f7bc7d099e2b]

	* scripts/last-dotplot:
	Refactor last-dotplot
	[2238466f36bd]

	* scripts/last-dotplot:
	Tweak the dotplot colors
	[8eb06508b3ed]

2017-10-24  Martin C. Frith  <Martin C. Frith>

	* src/CyclicSubsetSeed.cc, src/MultiSequence.cc, src/MultiSequence.hh,
	src/MultiSequenceQual.cc, src/ScoreMatrix.cc:
	Make the code a bit more robust
	[efb59c80bd48]

	* src/split/cbrc_split_aligner.cc,
	src/split/cbrc_unsplit_alignment.cc,
	src/split/cbrc_unsplit_alignment.hh, src/split/last-split.cc:
	Make last-split work with lastdb strand option
	[e6f6334cedb8]

	* doc/last-train.txt, scripts/last-train, src/LastEvaluer.cc,
	src/LastEvaluer.hh, src/alp/sls_pvalues.cpp, src/lastal.cc:
	Fix some E-value & last-train fails
	[c208904d9c3e]

2017-10-20  Martin C. Frith  <Martin C. Frith>

	* src/AlignmentWrite.cc, src/LastdbArguments.cc,
	src/LastdbArguments.hh, src/MultiSequence.cc, src/MultiSequence.hh,
	src/lastdb.cc:
	Add lastdb strand option
	[bef94bc275d5]

	* src/MultiSequence.hh, src/last.hh, src/lastal.cc, src/lastdb.cc,
	src/makefile, src/mcf_zstream.hh:
	Refactor
	[a4cdd7fbaee2]

2017-10-19  Martin C. Frith  <Martin C. Frith>

	* src/Alignment.hh, src/AlignmentWrite.cc, src/MultiSequence.cc,
	src/MultiSequence.hh, src/lastal.cc:
	Start implementing reverse strands in lastdb
	[5187bd412fb6]

	* src/MultiSequence.cc, src/MultiSequence.hh,
	src/MultiSequenceQual.cc:
	Refactor
	[3ba00f2e93e0]

	* src/MultiSequence.cc, src/MultiSequence.hh,
	src/MultiSequenceQual.cc, src/lastdb.cc:
	Refactor
	[69da6e43d607]

	* src/LastdbArguments.cc, src/MultiSequence.cc, src/MultiSequence.hh,
	src/lastal.cc:
	Refactor
	[284c69b1bf3e]

2017-10-10  Martin C. Frith  <Martin C. Frith>

	* scripts/last-train:
	Make last-train print the lastal version
	[c2ce08b5a76a]

	* src/Alphabet.cc, src/Alphabet.hh, src/MultiSequence.hh,
	src/lastal.cc, src/lastdb.cc:
	Refactor
	[52565bc1c7d7]

	* src/lastdb.cc:
	Refactor (I think)
	[02a9cb451bc7]

	* src/MultiSequence.cc, src/MultiSequence.hh,
	src/MultiSequenceQual.cc, src/lastal.cc:
	Refactor some code
	[88fa35342a52]

	* scripts/last-train, test/last-train-test.out, test/last-train-
	test.sh:
	Make last-train work with lastdb8
	[a7ef7848ad1e]

2017-10-06  Martin C. Frith  <Martin C. Frith>

	* doc/maf-convert.txt, scripts/maf-convert, test/maf-convert-test.out,
	test/maf-convert-test.sh:
	Add maf-convert -> chain
	[6635b482e6e2]

	* doc/last.txt, src/LastEvaluer.cc:
	Avoid some "can't get E-value parameters" errors
	[2c0cb7ef8842]

2017-10-03  Martin C. Frith  <Martin C. Frith>

	* doc/last-dotplot.txt, scripts/last-dotplot:
	Add text-rotation options to last-dotplot
	[20f5c97a3cfd]

	* scripts/last-dotplot:
	Fix mixed-up margin sizes in last-dotplot
	[f5f93e51ef53]

2017-09-27  Martin C. Frith  <Martin C. Frith>

	* src/makefile:
	Try to make the gz compilation work more portably
	[bf8efe69f160]

2017-09-26  Martin C. Frith  <Martin C. Frith>

	* scripts/last-dotplot, scripts/last-postmask, scripts/last-train,
	scripts/maf-convert, test/last-postmask-test.out, test/last-
	postmask-test.sh, test/last-test.sh:
	Add gz reading to: dotplot postmask train convert
	[592295375eb1]

2017-09-22  Martin C. Frith  <Martin C. Frith>

	* doc/last-parallel.txt, src/mcf_zstream.hh:
	Make the gz stuff compile on old computers
	[0602563ef4e2]

	* src/makefile:
	Try to make compilation more robust & portable
	[8a2e4af79c99]

	* doc/lastal.txt, doc/lastdb.txt, scripts/fastq-interleave, src/io.cc,
	src/io.hh, src/last-pair-probs.cc, src/lastal.cc, src/lastdb.cc,
	src/makefile, src/mcf_zstream.hh:
	Enable lastal, lastdb, etc to read .gz files
	[a530b1ee48f4]

	* doc/last-train.txt, scripts/last-train:
	Add option -k to last-train
	[80a016b17089]

	* doc/last-tuning.txt, doc/lastal.txt, src/LastalArguments.cc, test
	/last-test.out, test/last-test.sh:
	Add -x % option to lastal
	[ad7f5f953412]

2017-06-20  Martin C. Frith  <Martin C. Frith>

	* doc/last-train.txt, scripts/last-train, test/last-train-test.out,
	test/last-train-test.sh:
	Make it easier to feed stdin/pipe to last-train
	[b73f1146e688]

	* doc/lastal.txt, src/AlignmentWrite.cc, test/last-test.out:
	Add raw score to BlastTab+ format
	[56f960a740a3]

2017-06-15  Martin C. Frith  <Martin C. Frith>

	* scripts/last-postmask, scripts/last-train:
	Make last-train read sequence file "-" from stdin
	[f9ec9c71d72e]

	* doc/last-dotplot.txt, scripts/last-dotplot:
	Change last-dotplot's verbosity
	[5182d8528ce9]

	* src/LastEvaluer.cc, src/alp/sls_alignment_evaluer.cpp,
	src/alp/sls_alignment_evaluer.hpp, src/alp/sls_alp_data.cpp,
	src/alp/sls_alp_data.hpp:
	Enable E-values for some unusual scoring schemes
	[230d1abe4c5d]

2017-06-02  Martin C. Frith  <Martin C. Frith>

	* doc/last-papers.txt, doc/last-tutorial.txt:
	Update docs
	[c15cd2ae062d]

	* scripts/last-dotplot:
	last-dotplot: get bp-per-pixel faster
	[6a4915d5b5cb]

	* src/LastalArguments.cc, src/LastdbArguments.cc, src/getoptUtil.hh,
	src/makefile:
	Fix parsing of command-line options
	[9afba231262d]

2017-05-18  Martin C. Frith  <Martin C. Frith>

	* scripts/last-dotplot:
	last-dotplot: do e.g. chr7 annotations -> hg19.chr7 only if no
	ambiguity
	[a75b439f0cf2]

	* doc/last-dotplot.txt, scripts/last-dotplot:
	last-dotplot: add genePred and rmsk options
	[6e8ff424ce2b]

	* scripts/last-dotplot:
	last-dotplot: refactor
	[1ecdbf2ddb78]

	* scripts/last-dotplot:
	last-dotplot: get layer from BED score
	[93d47bb8527f]

	* scripts/last-dotplot:
	last-dotplot: start implementing "layers"
	[5e4e3f2cf68b]

	* scripts/last-dotplot:
	last-dotplot: parse BED more liberally
	[d086361eabec]

2017-05-17  Martin C. Frith  <Martin C. Frith>

	* scripts/last-dotplot:
	Refactor last-dotplot
	[09a9d7ef13ae]

2017-05-15  Martin C. Frith  <Martin C. Frith>

	* scripts/maf-convert:
	Make maf-convert to tab faster
	[0d11825c43b2]

	* doc/last-train.txt, scripts/last-train:
	Add lastal's -C option to last-train
	[791ec91ac03c]

2017-05-02  Martin C. Frith  <Martin C. Frith>

	* doc/last-dotplot.txt, scripts/last-dotplot:
	Add border options to last-dotplot
	[f3b6c666afad]

	* doc/last-dotplot.txt, scripts/last-dotplot:
	Add sequence order options to last-dotplot
	[5b2acb7fdb3e]

	* doc/last-dotplot.txt, scripts/last-dotplot:
	Tweak last-dotplot's documentation
	[db0ddc92f2ec]

2017-04-18  Martin C. Frith  <Martin C. Frith>

	* src/Alignment.cc, src/Centroid.cc, src/Centroid.hh:
	Refactor
	[cb934e010567]

	* doc/last-train.txt, scripts/last-train, test/last-train-test.out,
	test/last-train-test.sh:
	Improve last-train sampling for long queries, e.g. chromosomes
	[7c09e0d848f2]

2017-04-04  Martin C. Frith  <Martin C. Frith>

	* scripts/last-dotplot:
	Made last-dotplot print width & height.
	[3ca7aa4b27a8]

	* doc/last-dotplot.txt, scripts/last-dotplot:
	Added last-dotplot options to show sequence lengths.
	[1f46ab956351]

	* doc/last-dotplot.txt, scripts/last-dotplot:
	Added last-dotplot options to show BED features.
	[16060c00b129]

	* scripts/last-dotplot:
	Made last-dotplot faster, sometimes.
	[23de4eb3be1d]

2017-03-09  Martin C. Frith  <Martin C. Frith>

	* src/alp/sls_basic.hpp, src/split/cbrc_split_aligner.hh:
	Fixed compile errors with old compilers.
	[7872fdade23a]

2017-03-07  Martin C. Frith  <Martin C. Frith>

	* doc/lastal.txt, src/LastalArguments.cc, src/LastalArguments.hh,
	src/lastal.cc, test/last-test.out, test/last-test.sh:
	Added lastal -N option to quickly get the first hits per query.
	[b69999b5cd1b]

	* src/alp/sls_alignment_evaluer.cpp, src/alp/sls_basic.hpp,
	src/alp/sls_falp_alignment_evaluer.cpp,
	src/alp/sls_fsa1_pvalues.cpp, src/alp/sls_fsa1_pvalues.hpp,
	src/alp/sls_pvalues.cpp, src/alp/sls_pvalues.hpp:
	Bugfix: E-values were occasionally negative.
	[681c5acdf5ca]

2017-03-02  Martin C. Frith  <Martin C. Frith>

	* doc/last-dotplot.txt, scripts/last-dotplot:
	Enabled sequence ranges for last-dotplot.
	[85a72978fb7d]

	* doc/last-dotplot.txt, scripts/last-dotplot:
	Added trim options to last-dotplot.
	[bbc6f00e683b]

	* scripts/last-dotplot:
	Refactoring.
	[7b972338fe04]

2017-02-28  Martin C. Frith  <Martin C. Frith>

	* scripts/last-dotplot:
	Refactoring.
	[2c3511fa1734]

	* scripts/last-dotplot:
	Refactoring.
	[1b4db1600728]

	* scripts/last-dotplot:
	Refactoring.
	[cdb1e40c28e4]

	* doc/last-papers.txt, scripts/last-dotplot:
	Bugfix: dotplot left border misplaced (for some versions of
	python/PIL).
	[1514199bb31b]

2017-02-03  Martin C. Frith  <Martin C. Frith>

	* doc/lastdb.txt, src/LastdbArguments.cc:
	Tiny doc/help edits.
	[ec636cb2fe64]

	* src/split/last-split.cc:
	Bugfix: rarely, last-split output end-gaps with wrong score/don/acc.
	[ff7752714cef]

	* scripts/maf-convert, test/90089.maf, test/maf-convert-test.out, test
	/maf-convert-test.sh:
	Bugfix(?): made maf-convert to psl trim end-gaps.
	[c5591feba7a2]

2017-01-19  Martin C. Frith  <Martin C. Frith>

	* src/split/cbrc_split_aligner.cc, src/split/cbrc_split_aligner.hh,
	src/split/last-split.cc:
	Added don and acc to spliced alignment output.
	[138b43db3812]

	* src/split/cbrc_split_aligner.cc, src/split/last-split.cc:
	Refactoring.
	[39ef0c88bcaa]

2016-12-19  Martin C. Frith  <Martin C. Frith>

	* src/Centroid.cc:
	Just re-ordered some probability calculations.
	[c13b3ad70ddb]

	* src/Centroid.cc:
	Refactoring.
	[a31864221c04]

	* src/Centroid.cc:
	Made lastal's probabilistic alignment faster.
	[d2813c5ef29c]

	* src/Centroid.cc:
	Refactoring.
	[3323a24e4185]

	* src/Centroid.cc, src/Centroid.hh:
	Refactoring.
	[07185ef5ae09]

	* src/Centroid.cc, src/Centroid.hh:
	Refactoring.
	[23d7d4d65391]

2016-12-16  Martin C. Frith  <Martin C. Frith>

	* src/Centroid.cc:
	Made lastal's probabilistic alignment faster, for FASTA queries.
	[8a5fff275e58]

	* src/Centroid.cc, src/GappedXdropAligner.cc,
	src/GappedXdropAligner2qual.cc, src/GappedXdropAlignerInl.hh,
	src/GappedXdropAlignerPssm.cc, src/GeneralizedAffineGapCosts.cc,
	src/GeneralizedAffineGapCosts.hh:
	Made lastal with asymmetric gap costs faster (but symmetric gap
	costs slower?)
	[370ee034eebc]

	* src/MultiSequence.cc, test/last-test.out, test/last-test.sh:
	Sped up fasta-reading, added tests.
	[5be7ba2d1f50]

2016-12-13  Martin C. Frith  <Martin C. Frith>

	* makefile:
	Bugfix: the previous update put junk in the zip-file.
	[3e3e4e67c69d]

	* .hgignore, doc/last-split.txt, doc/last-tuning.txt, doc/lastal.txt,
	doc/lastdb.txt, makefile, src/lastal.cc, src/lastdb.cc,
	src/makefile, src/split/cbrc_split_aligner.cc:
	Added 8-byte LAST!
	[d6d939a854fd]

2016-12-09  Martin C. Frith  <Martin C. Frith>

	* makefile, src/makefile:
	Refactoring.
	[cd7349e81e02]

	* src/makefile:
	Refactoring.
	[59c5f7c8532e]

2016-12-08  Martin C. Frith  <Martin C. Frith>

	* src/DiagonalTable.hh, src/LastalArguments.hh, src/MultiSequence.hh,
	src/SegmentPair.hh, src/SegmentPairPot.cc, src/SegmentPairPot.hh,
	src/SubsetSuffixArray.hh, src/makefile:
	Allow integers >= 2^32 in even more places.
	[c24adb93f907]

2016-12-06  Martin C. Frith  <Martin C. Frith>

	* src/LastalArguments.hh, src/SubsetSuffixArray.hh,
	src/SubsetSuffixArraySearch.cc, src/lastal.cc:
	Allow integers >= 2^32 in still more places.
	[4d18df171b8d]

	* src/LastdbArguments.cc, src/LastdbArguments.hh,
	src/SubsetSuffixArray.cc, src/SubsetSuffixArray.hh:
	Refactoring.
	[a32c6d227241]

	* src/LastalArguments.hh, src/LastdbArguments.hh,
	src/SubsetSuffixArray.hh, src/SubsetSuffixArraySearch.cc,
	src/SubsetSuffixArraySort.cc, src/split/cbrc_split_aligner.cc,
	src/split/cbrc_split_aligner.hh:
	Allow integers >= 2^32 in yet more places.
	[e55f2a3d8569]

	* src/LastalArguments.cc, src/LastalArguments.hh,
	src/LastdbArguments.hh, src/SubsetSuffixArray.cc,
	src/SubsetSuffixArray.hh, src/lastal.cc, src/lastdb.cc:
	Allow integers >= 2^32 in more places.
	[e8c20a8e0137]

2016-12-02  Martin C. Frith  <Martin C. Frith>

	* doc/last-split.txt, src/split/cbrc_split_aligner.cc,
	src/split/cbrc_split_aligner.hh, src/split/last-split.cc, test/last-
	split-test.out:
	Added "sense" to last-split -d2 output.
	[c332e3b4ece7]

2016-11-24  Martin C. Frith  <Martin C. Frith>

	* src/split/cbrc_split_aligner.cc, src/split/cbrc_split_aligner.hh:
	Made last-split a bit faster.
	[604434e30b9b]

	* src/split/cbrc_split_aligner.cc:
	Enabled last-split -g to read multi-volume genomes.
	[39d60e63649c]

	* src/split/cbrc_split_aligner.cc, src/split/cbrc_split_aligner.hh:
	Refactoring.
	[e390c8a6b953]

	* src/split/cbrc_split_aligner.cc, src/split/cbrc_split_aligner.hh:
	Refactoring.
	[a651f673eccd]

	* src/split/cbrc_split_aligner.cc:
	Refactoring.
	[3cf4563e1e06]

	* src/split/cbrc_split_aligner.cc:
	Made last-split -g check for alignment coordinates beyond ends of
	sequences.
	[271148f2fd22]

	* src/split/cbrc_split_aligner.cc, src/split/cbrc_split_aligner.hh,
	test/last-test.sh:
	Refactoring.
	[3bcd06103556]

2016-11-22  Martin C. Frith  <Martin C. Frith>

	* doc/last-split.txt, src/split/cbrc_split_aligner.cc,
	src/split/cbrc_split_aligner.hh, src/split/last-split-main.cc,
	src/split/last-split.cc, src/split/last-split.hh, src/stringify.hh,
	test/last-split-test.out:
	Added last-split -b option, to skip troublesome query sequences.
	[99208596e2df]

2016-11-15  Martin C. Frith  <Martin C. Frith>

	* src/split/cbrc_split_aligner.cc:
	Made last-split's spliced alignment a bit faster.
	[7a7418e343ec]

	* src/split/cbrc_split_aligner.hh, src/split/last-split.cc:
	Put memory info in last-split verbose output.
	[a9b828b51430]

	* test/maf-convert-test.out, test/maf-convert-test.sh:
	Added tests for maf-convert.
	[b9fb391b111f]

	* doc/maf-convert.txt, scripts/maf-convert:
	Added maf-convert -j option!
	[e80789dbe5a9]

	* scripts/maf-convert:
	Refactoring.
	[60a355a2060c]

2016-11-11  Martin C. Frith  <Martin C. Frith>

	* scripts/maf-convert:
	Refactoring.
	[640ec6e760a4]

	* scripts/maf-convert:
	Refactoring.
	[2b817a03775e]

	* scripts/maf-convert:
	Refactoring.
	[2e56e3884ce1]

	* scripts/maf-convert:
	Minor modifications.
	[3a530469efd4]

	* scripts/maf-convert:
	Minor modifications.
	[a6f7e46b53e8]

	* scripts/maf-convert:
	Minor modifications.
	[4b680ca58d11]

	* scripts/maf-convert:
	Minor modifications.
	[ed5ab3b3b096]

	* scripts/maf-convert:
	Refactoring.
	[49af9e116654]

	* scripts/maf-convert:
	Refactoring.
	[90cdd16c533d]

	* scripts/maf-convert:
	Refactoring.
	[5a56c7267682]

	* scripts/maf-convert:
	Minor modifications.
	[5718d170c521]

	* scripts/maf-convert:
	Refactoring.
	[5e862e6f4593]

	* scripts/maf-convert:
	Minor modifications.
	[1b0f793a2df3]

	* scripts/maf-convert:
	Refactoring.
	[fd3de758e253]

	* scripts/maf-convert:
	Refactoring.
	[17d5f147e3e8]

	* scripts/maf-convert:
	Minor refactoring.
	[9137dbc02893]

	* scripts/maf-convert:
	Refactoring.
	[b6a9b0636a43]

	* scripts/maf-convert:
	Made maf-convert a bit faster.
	[6c8368485b73]

	* scripts/maf-convert:
	Refactoring.
	[21080ba28e06]

2016-11-10  Martin C. Frith  <Martin C. Frith>

	* scripts/maf-convert:
	Refactoring.
	[e289a5a60161]

	* scripts/maf-convert:
	Refactoring.
	[08dff31a448d]

	* scripts/maf-convert:
	Refactoring.
	[a6e60fafb4c7]

	* scripts/maf-convert:
	Refactoring.
	[3e274b1d6e63]

	* scripts/maf-convert:
	Refactoring.
	[3fdccdc68124]

	* src/LastalArguments.cc:
	Reduced memory use of lastal with multi-threads.
	[3d55bdf04914]

	* doc/last-train.txt, src/split/cbrc_split_aligner.cc, test/102.maf,
	test/last-split-test.out, test/last-split-test.sh:
	Reverted an unintended minor change in last-split output.
	[41a1f195a956]

2016-11-04  Martin C. Frith  <Martin C. Frith>

	* src/split/cbrc_split_aligner.cc, src/split/cbrc_split_aligner.hh:
	Refactoring.
	[ebfe8b16e512]

	* scripts/last-train:
	Reduced last-train's default sample size to 1 million.
	[3fa8121533e6]

	* src/split/cbrc_split_aligner.cc, src/split/cbrc_split_aligner.hh:
	Made last-split's spliced alignment a bit faster, maybe.
	[9e43ca208315]

	* src/split/cbrc_split_aligner.cc, src/split/cbrc_split_aligner.hh:
	Refactoring.
	[15807aae76c1]

	* src/split/cbrc_split_aligner.cc, src/split/cbrc_split_aligner.hh:
	Refactoring.
	[a08e93976d22]

	* src/split/cbrc_split_aligner.cc, src/split/cbrc_split_aligner.hh:
	Refactoring.
	[5a2487a536ff]

	* doc/last-train.txt, scripts/last-train,
	src/split/cbrc_split_aligner.cc, src/split/cbrc_split_aligner.hh:
	Documented rows/columns of last-train matrices.
	[ef684382d11c]

2016-11-01  Martin C. Frith  <Martin C. Frith>

	* scripts/last-train:
	Made last-train print matrices more prettily.
	[ea0e36883c48]

	* doc/last-train.txt, scripts/last-train:
	Improved last-train doc.
	[567a4a35cd4b]

2016-10-25  Martin C. Frith  <Martin C. Frith>

	* doc/last-train.txt, scripts/last-train:
	Made last-train use a random sample of the query sequences.
	[ae037299752f]

	* scripts/last-postmask:
	Made last-postmask a bit faster.
	[5e99b6e235e0]

2016-09-29  Martin C. Frith  <Martin C. Frith>

	* test/last-test.out, test/last-test.sh:
	Added (incomplete) tests for gapless overlap alignment.
	[19b58d988059]

	* src/LastalArguments.cc, src/gaplessPssmXdrop.cc,
	src/gaplessPssmXdrop.hh, src/gaplessTwoQualityXdrop.cc,
	src/gaplessTwoQualityXdrop.hh, src/gaplessXdrop.cc,
	src/gaplessXdrop.hh, src/lastal.cc:
	Enabled gapless overlap alignment.
	[8f2bf0e299a1]

	* src/lastal.cc:
	Refactoring.
	[64ac7ea995de]

2016-09-16  Martin C. Frith  <Martin C. Frith>

	* doc/lastal.txt, doc/lastdb.txt, scripts/last-dotplot:
	Fixed last-dotplot axis labels for breaking change in Pillow 3.0.
	[a0074597cb5d]

2016-09-01  Martin C. Frith  <Martin C. Frith>

	* doc/last-map-probs.txt, doc/last-pair-probs.txt, doc/last-
	parallel.txt, doc/last-split.txt, doc/last-tutorial.txt, examples
	/last-bisulfite-paired.sh, examples/last-bisulfite.sh,
	test/bs100.maf, test/maf-convert-test.out:
	Replaced score thresholds with significance thresholds.
	[d48e9d4a7268]

	* doc/last-split.txt, src/split/last-split-main.cc, src/split/last-
	split.cc, test/last-split-test.out:
	Reduced the default score threshold for spliced alignment.
	[e632c170bdd2]

2016-08-30  Martin C. Frith  <Martin C. Frith>

	* doc/last-tuning.txt, doc/lastal.txt, doc/lastdb.txt,
	src/LastalArguments.cc, src/LastdbArguments.cc:
	Reduced lastal memory usage with multi volumes or threads.
	[e0e21e5549dd]

2016-08-01  Martin C. Frith  <Martin C. Frith>

	* scripts/last-train:
	Fixed last-train crash with gap existence cost < 0.
	[9a03622aa2c0]

	* src/TwoQualityScoreMatrix.cc, src/TwoQualityScoreMatrix.hh,
	src/lastal.cc:
	Made lastal startup yet faster for fastq-versus-fastq.
	[3d9a91ae8385]

	* src/TwoQualityScoreMatrix.cc, src/TwoQualityScoreMatrix.hh:
	Refactoring.
	[75fb5e4bd955]

2016-07-20  Martin C. Frith  <Martin C. Frith>

	* src/TwoQualityScoreMatrix.cc, src/qualityScoreUtil.hh:
	Made lastal startup even faster for fastq-versus-fastq.
	[b29ac42364b3]

	* src/TwoQualityScoreMatrix.cc:
	Made lastal startup faster for fastq-versus-fastq.
	[be0485aed801]

	* src/OneQualityScoreMatrix.cc, src/QualityPssmMaker.cc,
	src/TwoQualityScoreMatrix.cc, src/qualityScoreUtil.hh:
	Refactoring.
	[ba10c9dd420f]

2016-07-05  Martin C. Frith  <Martin C. Frith>

	* src/SubsetSuffixArraySearch.cc:
	Bugfix: lastal with -l0 was not reliable, I think.
	[60738c7a24e3]

	* src/LastalArguments.cc:
	Allowed gap open costs < 0.
	[4513e0b7e26d]

2016-05-20  Martin C. Frith  <Martin C. Frith>

	* src/lastal.cc:
	Maybe made lastal faster in some cases.
	[bb03593936dc]

	* src/GappedXdropAligner.hh, src/GappedXdropAligner3frame.cc:
	Refactoring.
	[788dd86f42f0]

	* src/Centroid.cc, src/GappedXdropAligner.cc,
	src/GappedXdropAligner.hh, src/GappedXdropAligner2qual.cc,
	src/GappedXdropAlignerPssm.cc:
	Refactoring.
	[eea957b121e8]

	* src/Centroid.cc:
	Refactoring.
	[db4de3a2e6a3]

	* src/Centroid.hh, src/GappedXdropAligner.cc,
	src/GappedXdropAligner.hh, src/GappedXdropAligner3frame.cc:
	Refactoring.
	[a317e3410f24]

2016-05-19  Martin C. Frith  <Martin C. Frith>

	* src/Centroid.cc, src/Centroid.hh, src/GappedXdropAligner.cc,
	src/GappedXdropAligner.hh, src/GappedXdropAligner3frame.cc:
	Refactoring.
	[12fa981e66d0]

	* src/alp/sls_alp_data.cpp, src/alp/sls_alp_data.hpp,
	src/alp/sls_basic.cpp, src/alp/sls_basic.hpp, src/alp/sls_fsa1.cpp,
	src/alp/sls_fsa1_utils.cpp, src/alp/sls_fsa1_utils.hpp:
	Tried to fix compile error on Cygwin (I don't fully understand
	this).
	[21d485934bef]

2016-03-31  Martin C. Frith  <Martin C. Frith>

	* doc/lastal.txt, src/LastalArguments.cc:
	Tried to document lastal options more clearly.
	[9ecd0219342e]

2016-03-30  Martin C. Frith  <Martin C. Frith>

	* test/last-test.out, test/last-test.sh:
	Added a test for minimum-difference alignment.
	[3eebddccaf4e]

	* doc/last-tuning.txt, doc/lastal.txt, src/Alignment.cc,
	src/Alignment.hh, src/GreedyXdropAligner.cc,
	src/GreedyXdropAligner.hh, src/LastalArguments.cc,
	src/LastalArguments.hh, src/lastal.cc, src/makefile, test/last-
	test.out:
	Added lastal option -M for fast-but-crude minimum-difference
	alignment!
	[a1fc3309828f]

	* doc/lastal.txt, src/LastEvaluer.cc, src/LastEvaluer.hh,
	src/LastalArguments.cc, src/LastalArguments.hh, src/lastal.cc, test
	/last-test.out, test/last-test.sh:
	Added DNA-versus-protein alignment without frameshifts (-F0).
	[cf14b8c39bf9]

2016-03-29  Martin C. Frith  <Martin C. Frith>

	* doc/lastal.txt, src/Alignment.cc, src/Alignment.hh,
	src/LastalArguments.cc, src/lastal.cc:
	! Made lastal's lowercase/repeat masking faster & slightly
	different.
	[a282cc2f6937]

2016-03-28  Martin C. Frith  <Martin C. Frith>

	* doc/lastal.txt, src/Alignment.cc, src/Alignment.hh, src/lastal.cc:
	Added warning about overlap alignment (-T1) to doc; refactoring.
	[87f9c581e48a]

2016-03-11  Martin C. Frith  <Martin C. Frith>

	* doc/last-tuning.txt, doc/lastal.txt, doc/lastdb.txt,
	src/LastalArguments.cc, src/LastdbArguments.cc, src/lastal.cc, test
	/last-test.out, test/last-test.sh:
	Added minimizer doc & test, tweaked lastal verbose messages.
	[323c152700e9]

2016-03-10  Martin C. Frith  <Martin C. Frith>

	* src/LastalArguments.cc, src/lastal.cc, test/last-test.out:
	Made lastal's informational messages less verbose.
	[c4a1a839f250]

	* src/CyclicSubsetSeed.hh, src/SubsetSuffixArray.cc,
	src/SubsetSuffixArray.hh, src/lastdb.cc:
	Maybe reduced lastdb's memory use in some cases.
	[811b0eaa631a]

	* src/lastdb.cc:
	Refactoring.
	[864cd331324f]

	* doc/lastdb.txt, src/LastdbArguments.cc, src/LastdbArguments.hh,
	src/lastdb.cc, src/makefile:
	Added -P multi-thread option to lastdb (for tantan only, so far).
	[6b028abf6969]

	* src/lastal.cc, src/makefile, src/threadUtil.hh:
	Refactoring.
	[2ad307f63f32]

	* src/LastalArguments.cc, src/LastalArguments.hh,
	src/LastdbArguments.cc, src/LastdbArguments.hh, src/lastal.cc,
	src/lastdb.cc:
	Get the program name for error/warning/help messages from the
	command line.
	[565f7858e80f]

2016-03-09  Martin C. Frith  <Martin C. Frith>

	* src/MultiSequence.hh, src/lastal.cc:
	Refactoring.
	[1bdaa28a80c8]

	* src/lastdb.cc:
	Re-ordered some lastdb computations.
	[63c3bff61406]

	* src/Mmap.hh, src/MultiSequence.cc, src/MultiSequence.hh,
	src/MultiSequenceQual.cc, src/SubsetSuffixArraySort.cc,
	src/VectorOrMmap.hh, src/fileMap.cc, src/fileMap.hh:
	Refactoring.
	[b87ee4885cad]

	* src/LastalArguments.cc, src/LastalArguments.hh,
	src/LastdbArguments.cc, src/LastdbArguments.hh,
	src/SubsetMinimizerFinder.cc, src/SubsetMinimizerFinder.hh,
	src/SubsetSuffixArray.cc, src/SubsetSuffixArray.hh, src/lastal.cc,
	src/lastdb.cc, src/makefile:
	Added minimizers (undocumented for now).
	[737a3da90ac8]

2016-03-08  Martin C. Frith  <Martin C. Frith>

	* doc/bisulfite.txt, doc/last-tuning.txt, doc/last.txt,
	src/CyclicSubsetSeed.cc, src/SubsetSuffixArray.cc, src/lastal.cc,
	src/lastdb.cc:
	Refactoring & doc updates.
	[de73bebc7110]

2016-02-15  Martin C. Frith  <Martin C. Frith>

	* src/CyclicSubsetSeed.hh, src/SubsetSuffixArraySort.cc:
	Refactoring.
	[30acd9c613ab]

	* scripts/maf-convert, test/maf-convert-test.out:
	Made maf-convert -> sam indicate mismatches.
	[78178e514854]

	* scripts/maf-convert:
	Made maf-convert -> sam check if the alignment is pair-wise.
	[91f69e34ec9e]

2016-02-05  Martin C. Frith  <Martin C. Frith>

	* doc/lastal.txt, src/Alignment.hh, src/AlignmentWrite.cc,
	src/LastalArguments.cc, src/lastal.cc, test/last-test.out, test
	/last-test.sh:
	Added BlastTab+ output option to lastal.
	[7cc4399c5980]

	* src/Alignment.hh, src/AlignmentWrite.cc, test/last-test.out:
	Slightly changed the sort order for lastal BlastTab output.
	[749f3855f465]

2016-01-25  Martin C. Frith  <Martin C. Frith>

	* src/lastal.cc:
	Made multi-thread lastal start writing output sooner.
	[0410af8bd5db]

	* doc/last.txt, doc/lastal.txt, makefile, src/lastal.cc, src/makefile:
	Made it usable with old compilers that lack C++11.
	[9bed0a398a5e]

2015-12-16  Martin C. Frith  <Martin C. Frith>

	* doc/FAQ.txt:
	FAQ update (thanks: Torben Nielsen).
	[2011b377a29a]

	* src/lastal.cc:
	Made lastal write its output ASAP.
	[1783670288c3]

	* src/lastal.cc:
	Made lastal sort alignments more efficiently for single-volume
	databases.
	[64899ae7fa4b]

	* src/lastal.cc:
	Multi-threaded lastal option -K and BlastTab sorting.
	[6e991b42c767]

2015-12-15  Martin C. Frith  <Martin C. Frith>

	* src/lastal.cc:
	Made lastal with option -K more efficient (maybe).
	[4a0c05e2d51a]

	* src/lastal.cc:
	Refactoring.
	[777670671dc8]

	* src/lastal.cc:
	Refactoring.
	[0ddd41e5aeda]

	* src/lastal.cc:
	Refactoring.
	[d7a43de7f386]

2015-12-07  Martin C. Frith  <Martin C. Frith>

	* doc/lastal.txt, test/last-test.out, test/last-test.sh:
	Added doc & test for lastal -K.
	[e52e4e83c604]

	* src/LastalArguments.cc, src/LastalArguments.hh, src/lastal.cc:
	Added lastal option -K to omit redundant alignments!
	[0eebbb14427e]

	* src/lastal.cc:
	Refactoring.
	[0b167d5b2d45]

	* src/Alignment.hh, src/AlignmentWrite.cc:
	Started to implement culling of final alignments in lastal.
	[3eb0de8a8df7]

	* doc/Makefile, doc/maf-cull.txt, scripts/maf-cull:
	Removed maf-cull script.
	[2fabaf7ff76e]

	* src/Alignment.hh, src/AlignmentWrite.cc:
	Refactoring.
	[2267bb7daf5c]

	* src/AlignmentWrite.cc:
	Refactoring.
	[046e5c339763]

	* src/Alignment.hh, src/AlignmentWrite.cc:
	Refactoring.
	[d01df25c81fc]

2015-12-02  Martin C. Frith  <Martin C. Frith>

	* doc/last-parallel.txt:
	Added missing parallel doc.
	[d323c685c625]

	* doc/Makefile, doc/last-tutorial.txt, doc/lastal.txt,
	src/LastalArguments.cc:
	Doc update.
	[73a0024f50fe]

	* doc/last-train.txt, scripts/last-train:
	Added -P multithread option to last-train.
	[d07ada895589]

	* makefile, src/lastal.cc, src/makefile:
	Added multi-threading option to lastal!
	[4174fdbdb9a1]

	* doc/lastal.txt, src/LastalArguments.cc, src/LastalArguments.hh,
	src/lastal.cc:
	Implementing lastal multi-threading option...
	[e3dda6a85d2c]

	* src/lastal.cc:
	Refactoring (preparing for multi-threading).
	[b3b9c8105af2]

2015-12-01  Martin C. Frith  <Martin C. Frith>

	* src/lastal.cc:
	Refactoring.
	[381ccbcecbd6]

	* src/lastal.cc:
	Refactoring.
	[6b95a28baa04]

	* src/lastal.cc:
	Refactoring.
	[60458b778c8f]

	* src/lastal.cc:
	Refactoring.
	[178f46036712]

	* src/MultiSequence.hh, src/lastal.cc:
	Refactoring.
	[bbc2d1f0d4c3]

	* src/LastalArguments.cc:
	Refactoring.
	[5b71e038f64c]

	* src/Centroid.cc, src/Centroid.hh, src/lastal.cc:
	Refactoring.
	[212ed2870152]

2015-11-30  Martin C. Frith  <Martin C. Frith>

	* src/last-pair-probs.cc:
	Made it compilable as C++11/14.
	[63ed317630ce]

	* src/Alignment.hh, src/AlignmentWrite.cc, src/lastal.cc:
	Refactoring.
	[d030a01fccf9]

	* src/Alignment.hh, src/lastal.cc:
	Refactoring.
	[c50e75bffe3c]

2015-11-27  Martin C. Frith  <Martin C. Frith>

	* src/Alignment.hh, src/AlignmentWrite.cc:
	Refactoring.
	[df54cf3b18e9]

	* src/AlignmentWrite.cc:
	Refactoring.
	[74b0d4178298]

	* src/AlignmentWrite.cc:
	Refactoring.
	[a334617380ad]

	* src/AlignmentWrite.cc:
	Refactoring.
	[21cb3a092cbd]

	* src/AlignmentWrite.cc:
	Refactoring.
	[43d75157a165]

	* src/AlignmentWrite.cc:
	Refactoring.
	[a3907f2012f7]

	* src/AlignmentWrite.cc:
	Refactoring.
	[06ea31f0120c]

	* src/AlignmentWrite.cc:
	Refactoring.
	[241f58456df3]

	* src/AlignmentWrite.cc:
	Refactoring.
	[0eb6978e222a]

2015-11-20  Martin C. Frith  <Martin C. Frith>

	* src/lastal.cc, test/last-test.out:
	Another minor change to lastal with option -k > 1.
	[b509ae9545be]

	* src/LastalArguments.cc:
	Allow lastal option -j0 with -F (not very useful).
	[4f2344b44d4d]

	* src/LastalArguments.cc, test/last-test.out:
	Bigger default query batch size for fastq/prb & multi-volume
	database.
	[1cb70c761bf9]

	* test/last-test.out:
	Updated the test output.
	[74eb94c11383]

	* src/Alignment.hh, src/AlignmentWrite.cc, src/MultiSequence.hh,
	src/lastal.cc:
	Changed lastal output order; slight change to results if -k > 1.
	[e1c86329b41a]

	* doc/lastal.txt, src/Alignment.hh, src/AlignmentWrite.cc,
	src/MultiSequence.hh, src/lastal.cc:
	Refactoring.
	[c5b43f3942f5]

2015-11-18  Martin C. Frith  <Martin C. Frith>

	* src/Alignment.cc, src/AlignmentWrite.cc:
	Refactoring.
	[838668ca264d]

	* doc/last-tutorial.txt, test/last-test.out:
	Updated test & doc.
	[b12e4c1d999a]

	* src/Alignment.hh, src/AlignmentWrite.cc, src/lastal.cc:
	Made lastal write BlastTab output in a similar order to BLAST!
	[00cae2afb562]

2015-11-17  Martin C. Frith  <Martin C. Frith>

	* src/AlignmentWrite.cc:
	Refactoring.
	[f1581f1fc4ec]

	* src/AlignmentWrite.cc:
	Made lastal faster at writing BlastTab format.
	[cd6e85f23d38]

	* src/AlignmentWrite.cc:
	Made lastal faster at writing tab format.
	[74e411702158]

	* src/AlignmentWrite.cc:
	Refactoring.
	[17392da5a692]

2015-10-27  Martin C. Frith  <Martin C. Frith>

	* scripts/last-train:
	Made last-train more robust to very low counts.
	[b3e3fe97d4cf]

2015-10-26  Martin C. Frith  <Martin C. Frith>

	* src/lastal.cc, test/last-test.out:
	Tiny change to lastal's output header.
	[5bd23cb12883]

	* doc/lastal.txt, src/Alignment.hh, src/AlignmentWrite.cc,
	src/LastEvaluer.hh, src/LastalArguments.cc, src/lastal.cc, test
	/last-test.out, test/last-test.sh:
	Added BlastTab output format to lastal!
	[4809ea9e1988]

	* build/seed-doc.sh, build/seed-inc.sh, doc/last-tuning.txt,
	doc/lastal.txt, src/AlignmentWrite.cc, src/LastalArguments.cc,
	src/lastal.cc, test/last-test.out, test/last-test.sh:
	Enabled specifying lastal's output format by name.
	[211878d3688d]

	* scripts/maf-convert, test/maf-convert-test.out, test/maf-convert-
	test.sh:
	Bugfix: maf-convert's blastTab coordinates were wrong for reverse
	strands.
	[74633c5a4f96]

2015-10-21  Martin C. Frith  <Martin C. Frith>

	* src/split/cbrc_split_aligner.cc:
	Made last-split's spliced alignment faster, sometimes.
	[cff029a6de15]

	* doc/Makefile, doc/last-dotplot.txt, doc/last-scripts.txt:
	Updated last-dotplot doc.
	[2538ba367b8e]

2015-10-20  Martin C. Frith  <Martin C. Frith>

	* scripts/last-dotplot:
	Added sequence-choosing options to last-dotplot.
	[fbb4c3b60998]

	* scripts/last-dotplot:
	Added unsequenced gap options to last-dotplot.
	[157301c5c6fd]

2015-10-19  Martin C. Frith  <Martin C. Frith>

	* scripts/last-dotplot:
	Just changed last-dotplot's help messages a bit.
	[94f7cda3507b]

	* scripts/last-dotplot:
	Refactoring.
	[33e285b3e428]

	* scripts/last-dotplot:
	Refactoring.
	[25c8084d7f6e]

	* scripts/last-dotplot:
	Refactoring.
	[504ecca38a3e]

	* scripts/last-dotplot:
	Refactoring.
	[9daf814fa381]

	* scripts/last-dotplot:
	Refactoring.
	[08cf5e7f1629]

	* scripts/last-dotplot:
	Refactoring.
	[3868726068b0]

	* scripts/last-dotplot:
	Refactoring.
	[50a6e3e00d36]

	* scripts/last-dotplot:
	Refactoring.
	[281e6460a6a9]

	* scripts/last-dotplot:
	Refactoring.
	[374bc3ee1115]

	* scripts/last-dotplot:
	Made last-dotplot much faster.
	[047baa399047]

2015-10-07  Martin C. Frith  <Martin C. Frith>

	* scripts/last-train:
	Made last-train handle zero counts more robustly.
	[0d044e3aead4]

	* scripts/last-train:
	Made last-train more likely to find a compatible version of LAST.
	[98e55d5d41c5]

2015-10-06  Martin C. Frith  <Martin C. Frith>

	* doc/last-train.txt, scripts/last-train:
	Added -s and -m options to last-train.
	[e8cf09bd022d]

	* doc/last-tuning.txt:
	Small update to tuning doc.
	[f98ce581a38b]

2015-10-05  Martin C. Frith  <Martin C. Frith>

	* test/last-test.out, test/last-test.sh:
	Streamlined the tests.
	[ec4c4187f22b]

	* doc/last-train.txt, doc/lastal.txt, scripts/last-train:
	Added -S option to last-train, and to docs.
	[32353d9dd57a]

	* src/LastalArguments.cc, test/last-test.out:
	Write new lastal option -S in the output header.
	[2b2db2cefc60]

	* test/last-test.out, test/last-test.sh:
	Added a test of new lastal option -S.
	[89d06373f97a]

	* src/LastalArguments.cc, src/LastalArguments.hh, src/lastal.cc:
	Added lastal option -S, to control non-strand-symmetric score
	matrices.
	[e8a8982ab0d4]

	* src/lastal.cc:
	Trivial refactoring.
	[a11429cccf9e]

	* src/lastal.cc:
	Refactoring.
	[20304fb4641e]

	* src/LastalArguments.cc, test/last-test.out:
	Removed unused parameter from lastal output header.
	[80ffd398f496]

	* src/lastal.cc:
	Refactoring.
	[af6046b15ef3]

	* src/LambdaCalculator.hh, src/lastal.cc:
	Refactoring.
	[6a46b82cb827]

	* src/LambdaCalculator.cc:
	Fixed lastal crash with all-zeros score matrix.
	[c96ccdecbc3d]

	* scripts/last-train, src/LambdaCalculator.cc,
	src/LambdaCalculator.hh:
	Refactoring.
	[1d409b1956bd]

	* makefile, src/makefile:
	Minor improvements to makefiles.
	[0144c188d702]

2015-09-17  Martin C. Frith  <Martin C. Frith>

	* src/SubsetSuffixArray.hh, src/SubsetSuffixArraySort.cc:
	Made lastdb with option -C (child table) much faster.
	[b7a24a664e7c]

	* src/SubsetSuffixArraySort.cc:
	Refactoring.
	[a02b90d73611]

	* build/seed-doc.sh, data/BISF.seed, data/BISR.seed, data/NEAR.seed,
	doc/last-map-probs.txt, doc/last-pair-probs.txt, doc/last-split.txt,
	doc/last-tutorial.txt, doc/lastdb.txt:
	Added NEAR seeding scheme.
	[0a0970754721]

2015-09-15  Martin C. Frith  <Martin C. Frith>

	* build/seed-doc.sh, data/MAM4.seed, data/MAM8.seed,
	data/MURPHY10.seed, data/PAM30.mat, data/YASS.seed:
	Edited the seed & matrix docs a bit.
	[9a6cc418fa40]

	* src/lastal.cc, src/lastdb.cc:
	Enabled setting lastal defaults in lastdb seed files.
	[22e3dd28e975]

	* src/LastalArguments.cc, src/LastalArguments.hh:
	Refactoring.
	[be5848927749]

2015-09-14  Martin C. Frith  <Martin C. Frith>

	* build/mat-inc.sh, data/YASS.seed, examples/yass.seed,
	src/CyclicSubsetSeed.hh, src/LastdbArguments.cc, src/lastdb.cc, test
	/last-test.sh:
	Added YASS built-in seeding scheme.
	[584332e02797]

	* build/seed-doc.sh, doc/Makefile, doc/lastdb.txt:
	Added seeding schemes doc.
	[aac31c1e87d5]

	* src/LastdbArguments.cc, src/lastdb.cc:
	Enabled setting lastdb options from seed file.
	[e1c2323dd42b]

	* src/LastdbArguments.cc, src/LastdbArguments.hh:
	Started implementing lastdb options from seed file.
	[4569b87239a1]

	* doc/lastdb.txt, src/lastdb.cc:
	Made lastdb option -u override -m. Made empty seed patterns errors.
	[120e1b508c42]

	* doc/lastdb.txt, src/LastdbArguments.cc, src/LastdbArguments.hh,
	src/lastdb.cc:
	Use at most one lastdb seed file.
	[9b084f6c31c1]

	* build/seed-inc.sh, data/BISF.seed, data/BISR.seed, data/MAM4.seed,
	data/MAM8.seed, data/MURPHY10.seed, src/CyclicSubsetSeed.cc,
	src/makefile:
	Refactoring.
	[05f764f87060]

	* examples/ublast.seed, examples/yass.seed, src/CyclicSubsetSeed.cc,
	src/CyclicSubsetSeed.hh, src/lastdb.cc:
	! Changed the format of subset seed files.
	[0ce60fad7662]

	* src/CyclicSubsetSeed.cc, src/CyclicSubsetSeed.hh:
	Refactoring.
	[10e68d99d4a6]

	* doc/Makefile, doc/last-doc.css:
	Made the docs a bit nicer.
	[1f390355766a]

	* src/Alphabet.cc, src/Alphabet.hh:
	Better error message for bad symbol in sequence.
	[dda77b988e20]

2015-08-31  Martin C. Frith  <Martin C. Frith>

	* doc/lastdb.txt, examples/ublast.seed, src/CyclicSubsetSeed.cc:
	Added MURPHY10 subset seed.
	[eb4023f396e8]

	* src/AlignmentWrite.cc, src/LastalArguments.cc, src/lastal.cc, test
	/last-test.out, test/last-test.sh:
	Allow fastq DNA-vs-protein, and non-fastq query vs fastq reference.
	[66892078f325]

	* src/Alignment.cc:
	Refactoring.
	[3846323cfaac]

	* src/Alignment.hh, src/AlignmentWrite.cc:
	Refactoring.
	[143b2b14a66e]

2015-08-27  Martin C. Frith  <Martin C. Frith>

	* build/mat-inc.sh, makefile:
	Refactoring.
	[79ae3ae7b4a5]

	* examples/hoxd70.mat, test/last-test.sh:
	Removed a redundant file.
	[99c825b5aef9]

	* doc/last-evalues.txt, scripts/fastq-interleave,
	src/LastalArguments.cc, src/SubsetSuffixArray.cc, src/io.hh,
	src/lastal.cc, src/lastdb.cc:
	Better error messages.
	[0aba501a185b]

2015-08-26  Martin C. Frith  <Martin C. Frith>

	* data/PAM30.mat:
	Added PAM30 matrix.
	[c369f122ffe2]

	* build/mat-doc.sh, doc/Makefile, doc/lastal.txt:
	Added last-matrices doc.
	[89fe6c768cdc]

	* doc/FAQ.txt, doc/Makefile, doc/last-doc.css, doc/last-tutorial.txt,
	doc/last.txt, doc/lastal.txt, doc/lastdb.txt:
	Tried to improve the docs.
	[9c69117fae26]

2015-08-25  Martin C. Frith  <Martin C. Frith>

	* makefile:
	Preserve file modification times in the zip.
	[7ba9d94e4282]

	* build/mat-inc.sh, data/AT77.mat, data/ATMAP.mat, data/BISF.mat,
	data/BISR.mat, data/BL62.mat, data/BL80.mat, data/HOXD70.mat,
	data/MIQS.mat, makefile, src/ScoreMatrix.cc, src/makefile:
	Refactoring.
	[7fa7f2f8e731]

	* src/LastalArguments.cc, src/LastalArguments.hh:
	Fixed a spelling error (thanks: Charles Plessy).
	[bd8c524eed6d]

	* test/last-test.sh:
	Increased test coverage.
	[9992dbc36b73]

2015-08-03  Martin C. Frith  <Martin C. Frith>

	* doc/Makefile, doc/last-doc.css, doc/last-papers.txt, doc/last-
	repeats.txt, doc/last-tuning.txt, doc/last-tutorial.txt,
	doc/lastdb.txt:
	Doc update.
	[fd377d1235d8]

	* src/LastEvaluer.cc, src/Mmap.hh, src/alp/sls_alp_regression.cpp,
	src/alp/sls_fsa1.hpp, src/alp/sls_fsa1_utils.hpp, src/lastal.cc,
	src/makefile:
	Minor code cleaning.
	[bd01a8f174c0]

2015-06-17  Martin C. Frith  <Martin C. Frith>

	* src/Alignment.cc:
	Bugfix: lastal expected ins/del counts not quite right with -T1.
	[c5717ac88a15]

2015-06-12  Martin C. Frith  <Martin C. Frith>

	* doc/Makefile, doc/last-train.txt, scripts/last-train:
	Added last-train!
	[d3784e21a84a]

	* src/alp/sls_alp.cpp, src/alp/sls_alp_data.cpp,
	src/alp/sls_alp_data.hpp, src/alp/sls_alp_sim.cpp:
	Updated to latest ALP lib: faster E-value calculations at lastal
	startup.
	[b66c549c9782]

2015-06-10  Martin C. Frith  <Martin C. Frith>

	* src/alp/sls_alp_data.hpp:
	Bugfix: no E-values for some unusual score parameters since v573.
	[f1cc20d37c37]

2015-06-08  Martin C. Frith  <Martin C. Frith>

	* src/split/last-split.cc:
	Made last-split with option --no-split keep expected counts.
	[580391aa98ee]

	* doc/lastal.txt, src/LastalArguments.cc:
	Documented lastal expected counts option.
	[f6b5dd71e329]

	* doc/lastal.txt, src/AlignmentPot.cc, src/AlignmentPot.hh:
	Made lastal non-redundantize gapped alignments more thoroughly.
	[ee75c619a976]

2015-05-26  Martin C. Frith  <Martin C. Frith>

	* doc/lastdb.txt, src/LastdbArguments.cc, src/LastdbArguments.hh,
	src/SubsetSuffixArray.cc, src/SubsetSuffixArray.hh,
	src/SubsetSuffixArraySearch.cc, src/SubsetSuffixArraySort.cc,
	src/lastdb.cc:
	Added child table option.
	[cea0cca54384]

	* src/SubsetSuffixArray.hh, src/SubsetSuffixArraySearch.cc:
	Made lastal seed-finding a bit faster, maybe.
	[13e7b7f0c2ea]

	* doc/last-tutorial.txt, src/SubsetSuffixArraySearch.cc:
	Minor refactoring.
	[2fb205c9b9b8]

	* src/SubsetSuffixArray.hh, src/SubsetSuffixArraySearch.cc:
	Refactoring.
	[bf5e3e7906be]

	* src/SubsetSuffixArray.hh, src/SubsetSuffixArraySearch.cc:
	Refactoring.
	[3303761b4296]

	* doc/last-papers.txt, src/SubsetSuffixArray.cc,
	src/SubsetSuffixArray.hh, src/SubsetSuffixArraySearch.cc,
	src/SubsetSuffixArraySort.cc:
	Refactoring.
	[99cc865985c6]

	* src/CyclicSubsetSeed.hh, src/SubsetSuffixArraySearch.cc:
	Made lastal seed-finding a bit faster.
	[271473f54610]

2015-05-21  Martin C. Frith  <Martin C. Frith>

	* src/SubsetSuffixArray.cc, src/SubsetSuffixArraySort.cc:
	Refactoring.
	[4445ae7683dd]

2015-05-19  Martin C. Frith  <Martin C. Frith>

	* src/alp/sls_alp.cpp, src/alp/sls_alp_data.hpp,
	src/alp/sls_fsa1_utils.hpp, test/last-test.out:
	Faster E-value calculations at lastal startup.
	[6c9ba2eba0f0]

2015-05-11  Martin C. Frith  <Martin C. Frith>

	* doc/last-evalues.txt, doc/maf-convert.txt, scripts/maf-convert, test
	/maf-convert-test.out:
	Added blasttab output format to maf-convert.
	[300742febddc]

2015-05-08  Martin C. Frith  <Martin C. Frith>

	* scripts/maf-convert:
	Put bit-score in maf-convert BLAST output.
	[e44314f7ae31]

2015-05-07  Martin C. Frith  <Martin C. Frith>

	* doc/FAQ.txt, doc/Makefile, doc/last-evalues.txt, doc/last-split.txt,
	doc/last-tutorial.txt, doc/lastal.txt:
	Added E-value documentation.
	[eef57c7b7ced]

	* scripts/maf-convert:
	Made maf-convert parse the new E-values.
	[e012aa1c692b]

	* scripts/last-map-probs, scripts/maf-convert, src/last-pair-probs.cc,
	test/last-pair-test.out:
	Put "extra" fields in LAST tabular format in key=value form.
	[70038812fc2b]

2015-05-01  Martin C. Frith  <Martin C. Frith>

	* src/LastalArguments.cc, src/ScoreMatrix.cc, src/lastal.cc, test
	/last-test.out:
	Added lastal E-value threshold options!
	[fa6ffddd33df]

	* src/LastalArguments.cc, src/LastalArguments.hh, src/lastal.cc:
	Started adding lastal E-value threshold options.
	[e2b03f7723df]

	* test/last-pair-test.out, test/last-test.out:
	Updated the tests.
	[972285260ce6]

	* src/LastalArguments.hh, src/lastal.cc:
	Added E-values to the lastal output!
	[ca14813caba2]

	* src/Alignment.hh, src/AlignmentWrite.cc, src/lastal.cc,
	src/makefile:
	Started using new E-value code in lastal.
	[448ad5e7e00a]

	* src/LastEvaluer.cc, src/LastEvaluer.hh, src/alp/njn_approx.hpp,
	src/alp/njn_doubletype.hpp, src/alp/njn_dynprogprob.cpp,
	src/alp/njn_dynprogprob.hpp, src/alp/njn_dynprogproblim.cpp,
	src/alp/njn_dynprogproblim.hpp, src/alp/njn_dynprogprobproto.cpp,
	src/alp/njn_dynprogprobproto.hpp, src/alp/njn_function.hpp,
	src/alp/njn_integer.hpp, src/alp/njn_ioutil.cpp,
	src/alp/njn_ioutil.hpp, src/alp/njn_localmaxstat.cpp,
	src/alp/njn_localmaxstat.hpp, src/alp/njn_localmaxstatmatrix.cpp,
	src/alp/njn_localmaxstatmatrix.hpp,
	src/alp/njn_localmaxstatutil.cpp, src/alp/njn_localmaxstatutil.hpp,
	src/alp/njn_matrix.hpp, src/alp/njn_memutil.hpp,
	src/alp/njn_random.cpp, src/alp/njn_random.hpp,
	src/alp/njn_root.hpp, src/alp/njn_uniform.hpp,
	src/alp/njn_vector.hpp, src/alp/sls_alignment_evaluer.cpp,
	src/alp/sls_alignment_evaluer.hpp, src/alp/sls_alp.cpp,
	src/alp/sls_alp.hpp, src/alp/sls_alp_data.cpp,
	src/alp/sls_alp_data.hpp, src/alp/sls_alp_regression.cpp,
	src/alp/sls_alp_regression.hpp, src/alp/sls_alp_sim.cpp,
	src/alp/sls_alp_sim.hpp, src/alp/sls_basic.cpp,
	src/alp/sls_basic.hpp, src/alp/sls_falp_alignment_evaluer.cpp,
	src/alp/sls_falp_alignment_evaluer.hpp, src/alp/sls_fsa1.cpp,
	src/alp/sls_fsa1.hpp, src/alp/sls_fsa1_parameters.cpp,
	src/alp/sls_fsa1_parameters.hpp, src/alp/sls_fsa1_pvalues.cpp,
	src/alp/sls_fsa1_pvalues.hpp, src/alp/sls_fsa1_utils.cpp,
	src/alp/sls_fsa1_utils.hpp, src/alp/sls_normal_distr_array.hpp,
	src/alp/sls_pvalues.cpp, src/alp/sls_pvalues.hpp:
	Added new E-value code (not used yet).
	[6bcbe452dbfb]

	* doc/last-tutorial.txt, doc/lastdb.txt, doc/lastex.txt,
	src/LastexArguments.cc, src/LastexArguments.hh,
	src/gumbel_params/common/ncbi_export.h,
	src/gumbel_params/corelib/ncbi_limits.h,
	src/gumbel_params/corelib/ncbidbg.hpp,
	src/gumbel_params/corelib/ncbistd.hpp,
	src/gumbel_params/corelib/ncbistl.hpp,
	src/gumbel_params/corelib/ncbistre.hpp,
	src/gumbel_params/corelib/ncbitype.h,
	src/gumbel_params/mcf_local_alignment_evaluer.cpp,
	src/gumbel_params/mcf_local_alignment_evaluer.hpp,
	src/gumbel_params/ncbi_pch.hpp, src/gumbel_params/njn_approx.hpp,
	src/gumbel_params/njn_doubletype.hpp,
	src/gumbel_params/njn_dynprogprob.cpp,
	src/gumbel_params/njn_dynprogprob.hpp,
	src/gumbel_params/njn_dynprogproblim.cpp,
	src/gumbel_params/njn_dynprogproblim.hpp,
	src/gumbel_params/njn_dynprogprobproto.cpp,
	src/gumbel_params/njn_dynprogprobproto.hpp,
	src/gumbel_params/njn_function.hpp,
	src/gumbel_params/njn_integer.hpp, src/gumbel_params/njn_ioutil.cpp,
	src/gumbel_params/njn_ioutil.hpp,
	src/gumbel_params/njn_localmaxstat.cpp,
	src/gumbel_params/njn_localmaxstat.hpp,
	src/gumbel_params/njn_localmaxstatmatrix.cpp,
	src/gumbel_params/njn_localmaxstatmatrix.hpp,
	src/gumbel_params/njn_localmaxstatutil.cpp,
	src/gumbel_params/njn_localmaxstatutil.hpp,
	src/gumbel_params/njn_matrix.cpp, src/gumbel_params/njn_matrix.hpp,
	src/gumbel_params/njn_memutil.hpp, src/gumbel_params/njn_root.hpp,
	src/gumbel_params/njn_vector.hpp, src/gumbel_params/random_gen.cpp,
	src/gumbel_params/sls_alp.cpp, src/gumbel_params/sls_alp.hpp,
	src/gumbel_params/sls_alp_data.cpp,
	src/gumbel_params/sls_alp_data.hpp,
	src/gumbel_params/sls_alp_regression.cpp,
	src/gumbel_params/sls_alp_regression.hpp,
	src/gumbel_params/sls_alp_sim.cpp,
	src/gumbel_params/sls_alp_sim.hpp,
	src/gumbel_params/sls_normal_distr_array.hpp,
	src/gumbel_params/sls_pvalues.cpp,
	src/gumbel_params/sls_pvalues.hpp,
	src/gumbel_params/util/random_gen.hpp, src/lastex.cc, src/makefile:
	Removed lastex!
	[717dd2226a7b]

2015-04-28  Martin C. Frith  <Martin C. Frith>

	* doc/Makefile, doc/last-papers.txt, doc/last.txt:
	Added LAST bibliography.
	[c9053fb2fbe3]

	* src/Alignment.cc, src/lastal.cc:
	Bugfix: lastal assertion failure with very low quality fastq.
	[66a8c1b7fc01]

	* src/OneQualityScoreMatrix.cc, src/OneQualityScoreMatrix.hh,
	src/lastal.cc:
	Made lastal in verbose mode show a table of per-quality scores.
	[b0ad1f063f51]

	* src/LastalArguments.cc, src/LastalArguments.hh, src/lastal.cc:
	Refactoring (preparing for lastal E-values).
	[c85b71eadcc8]

2015-04-17  Martin C. Frith  <Martin C. Frith>

	* doc/FAQ.txt, doc/last-split.txt:
	Doc tweaks.
	[f987c7e80959]

	* src/AlignmentWrite.cc:
	Refactoring.
	[8238029a5806]

2015-04-15  Martin C. Frith  <Martin C. Frith>

	* src/LambdaCalculator.cc:
	Bugfix: failure to calculate matrix lambda for e.g. match=5
	mismatch=-95.
	[801795072c71]

2015-04-13  Martin C. Frith  <Martin C. Frith>

	* test/last-test.out, test/last-test.sh:
	Future-proofed some tests.
	[ecb1a5ef56a5]

	* src/GeneralizedAffineGapCosts.cc, src/GeneralizedAffineGapCosts.hh,
	src/LastalArguments.cc, test/last-test.out:
	Bugfix: lastal probabilistic alignment aborted with large score
	parameters & unequal gap costs.
	[16a19884bf99]

2015-03-30  Martin C. Frith  <Martin C. Frith>

	* src/LambdaCalculator.cc, src/lastal.cc:
	Print matrix letter frequencies in verbose lastal output.
	[9168e46948a6]

	* doc/last.txt, src/CA_code/lambda_calculator.c,
	src/CA_code/lambda_calculator.h, src/CA_code/lubksb.c,
	src/CA_code/ludcmp.c, src/CA_code/nrutil.c, src/CA_code/nrutil.h,
	src/LambdaCalculator.cc, src/LambdaCalculator.hh, src/makefile:
	New LambdaCalculator code (thanks: Yutaro Konta).
	[8b9f32d02421]

	* src/makefile:
	Bugfix: The last-merge-batches --version option was unreliable.
	[3235314a5032]

2015-03-05  Martin C. Frith  <Martin C. Frith>

	* src/LastalArguments.cc, test/last-test.out:
	Don't write option F in the lastal header unless it's used.
	[f6801a8ce62f]

	* src/lastal.cc:
	Minor code reorganization.
	[2c9cb3de5450]

	* src/MultiSequence.cc, src/MultiSequence.hh,
	src/MultiSequenceQual.cc, test/last-test.out, test/last-test.sh,
	test/nano.fq:
	! Bugfix: the recent simple-sequence R option caused wrong maf q
	lines.
	[33fedff8cdb6]

2015-02-10  Martin C. Frith  <Martin C. Frith>

	* src/LastalArguments.cc, src/LastalArguments.hh, src/lastal.cc:
	Made lastal reject an empty matrix file.
	[011f449c1a67]

	* src/AlignmentWrite.cc, src/ScoreMatrix.cc, src/ScoreMatrix.hh:
	Refactoring.
	[b507c8d91783]

	* src/ScoreMatrix.cc:
	Better error message for bad score matrix.
	[cf5bc46a13d6]

	* doc/last-pair-probs.txt, doc/lastal.txt, doc/lastdb.txt,
	src/LastalArguments.cc, src/LastdbArguments.cc, src/makefile:
	Added --help, -V, --version options to lastdb & lastal.
	[91bce10f28af]

2015-01-30  Martin C. Frith  <Martin C. Frith>

	* doc/last-tutorial.txt, doc/lastal.txt, doc/lastdb.txt,
	examples/myalns.maf:
	Updated docs for repeat-marking/tantan.
	[334ae5489f3d]

	* src/LastalArguments.cc, src/LastdbArguments.cc, test/Q5GS15.fa, test
	/at-rich.fa, test/last-test.out, test/last-test.sh:
	Added tantan tests.
	[345720acbc59]

	* src/TantanMasker.cc, src/TantanMasker.hh, src/lastal.cc,
	src/lastdb.cc, src/makefile, src/tantan.cc, src/tantan.hh:
	Added tantan repeat-marking option (better late than never).
	[1c12aded271c]

	* src/makefile:
	Bugfix: The last-pair-probs --version option was unreliable.
	[66d3b14fb60c]

2015-01-29  Martin C. Frith  <Martin C. Frith>

	* src/LastalArguments.cc, src/LastalArguments.hh,
	src/LastdbArguments.cc, src/LastdbArguments.hh, src/lastal.cc,
	src/lastdb.cc:
	Implementing repeat-marking options...
	[28b2c142316e]

	* src/Alphabet.cc, src/Alphabet.hh, src/LastalArguments.cc,
	src/LastalArguments.hh, src/LastdbArguments.cc,
	src/LastdbArguments.hh, src/lastal.cc, src/lastdb.cc, src/split
	/last-split.cc:
	Started adding option whether-or-not to keep lowercase in input
	sequences.
	[73c162f7a5d2]

2015-01-26  Martin C. Frith  <Martin C. Frith>

	* doc/last-split.txt, doc/last-tutorial.txt,
	src/split/cbrc_unsplit_alignment.cc,
	src/split/cbrc_unsplit_alignment.hh, src/split/last-split.cc:
	If last-split is run twice, it now calculates the combined mismap
	prob.
	[1a1c407774f2]

2015-01-23  Martin C. Frith  <Martin C. Frith>

	* doc/lastal.txt, src/ScoreMatrix.cc:
	Added ATMAP substitution score matrix.
	[1689423027d6]

	* src/split/last-split.cc, test/last-split-test.out:
	Made last-split not print "# batch" lines (to simplify last-split |
	maf-swap | last-split).
	[488d84ce7ec1]

	* src/split/cbrc_split_aligner.cc:
	Made last-split accept per-base quality scores >= 64.
	[1419b21864b7]

2014-12-19  Martin C. Frith  <Martin C. Frith>

	* src/last-pair-probs-main.cc, test/last-pair-test.out:
	Added version option to last-pair-probs.
	[fb3745368a0c]

	* src/last-pair-probs-main.cc, src/last-pair-probs.cc, src/last-pair-
	probs.hh, test/last-pair-test.out, test/last-pair-test.sh:
	Made last-pair-probs write distance statistics to stdout, not
	stderr.
	[6aa0a194f64b]

2014-12-10  Martin C. Frith  <Martin C. Frith>

	* doc/last-pair-probs.txt, scripts/fastq-interleave, scripts/parallel-
	fastq, src/last-pair-probs-main.cc, src/last-pair-probs.cc,
	src/makefile, test/last-pair-test.out:
	Made last-pair-probs able to read interleaved pairs.
	[dc2c88c11662]

2014-12-09  Martin C. Frith  <Martin C. Frith>

	* src/ScoreMatrix.cc:
	Changed the MIQS default gap existence cost from 15 to 13.
	[29ee3f694b98]

	* src/last-pair-probs.cc:
	Added some checks for bad input to last-pair-probs.
	[5a21351e61c3]

	* src/last-pair-probs.cc:
	Refactoring.
	[f91a8863ee13]

2014-12-08  Martin C. Frith  <Martin C. Frith>

	* src/last-pair-probs.cc:
	Made last-pair-probs a bit faster.
	[47013cfde9cf]

	* src/last-pair-probs.cc:
	Made last-pair-probs faster.
	[fea2dae3ca09]

	* src/last-pair-probs.cc:
	Made last-pair-probs faster.
	[a392533917cf]

	* src/last-pair-probs.cc:
	Made last-pair-probs a bit slower, temporarily.
	[13fc043e92e2]

	* src/last-pair-probs.cc:
	Made last-pair-probs a bit faster.
	[405232c073ab]

	* src/last-pair-probs.cc:
	Refactoring.
	[5c963397fc74]

	* src/last-pair-probs.cc:
	Made last-pair-probs faster.
	[44a9db2972c4]

	* src/last-pair-probs.cc:
	Refactoring.
	[44e682fc4f66]

	* src/last-pair-probs.cc:
	Made last-pair-probs faster.
	[fc6ba2b54315]

	* src/last-pair-probs.cc:
	Refactoring.
	[79359b21b314]

2014-12-05  Martin C. Frith  <Martin C. Frith>

	* src/last-pair-probs.cc:
	Made last-pair-probs a bit faster, maybe.
	[93df261216e3]

	* src/last-pair-probs.cc:
	Made last-pair-probs a bit faster.
	[f840ffb18338]

	* doc/last-pair-probs.txt, src/last-pair-probs.cc:
	Made last-pair-probs much faster.
	[0ecfbfd618c7]

2014-12-03  Martin C. Frith  <Martin C. Frith>

	* doc/last-pair-probs.txt, examples/last-bisulfite-paired.sh,
	makefile, scripts/last-pair-probs, src/last-pair-probs-main.cc, src
	/last-pair-probs.cc, src/last-pair-probs.hh, src/makefile, test
	/last-pair-test.out:
	Made last-pair-probs faster (Python -> C++)!
	[0e7e23a7850a]

	* test/last-pair-test.out, test/last-pair-test.sh:
	Added some tests.
	[e5c72deb6ed3]

2014-12-01  Martin C. Frith  <Martin C. Frith>

	* test/bs1.fastq, test/bs2.fastq, test/last-pair-test.out, test/last-
	pair-test.sh, test/last-test.sh:
	Added tests of paired alignment.
	[a2bbd8f5e7e4]

	* src/SubsetSuffixArraySort.cc, src/lastal.cc, test/last-test.out,
	test/last-test.sh, test/ttttt.fa, test/tttttccccc.fa:
	Bugfix: lastdb option -i wasn't quite right since v497.
	[0f3545af3222]

2014-11-28  Martin C. Frith  <Martin C. Frith>

	* src/lastal.cc, src/lastdb.cc:
	Refactoring.
	[615bad2bf469]

	* src/LastdbArguments.hh, src/lastal.cc, src/lastdb.cc:
	Refactoring.
	[6b70fd6c4d5a]

2014-11-27  Martin C. Frith  <Martin C. Frith>

	* src/GeneticCode.cc, src/GeneticCode.hh:
	Refactoring.
	[1c9afaa16a28]

2014-11-26  Martin C. Frith  <Martin C. Frith>

	* doc/lastal.txt, src/ScoreMatrix.cc:
	Added MIQS substitution score matrix, for remote protein homology.
	[8532319b6abd]

	* src/Alphabet.cc, src/Alphabet.hh:
	Refactoring.
	[1d7c986d8f69]

	* src/Alignment.cc, src/Alphabet.cc, src/Alphabet.hh, src/lastal.cc,
	src/lastdb.cc, src/split/cbrc_split_aligner.cc:
	Refactoring (changed a name).
	[48967e20b286]

2014-11-17  Martin C. Frith  <Martin C. Frith>

	* src/SubsetSuffixArray.hh, src/SubsetSuffixArraySearch.cc:
	Made lastal with option -l or -m0 faster.
	[133919bd9cd4]

2014-10-30  Martin C. Frith  <Martin C. Frith>

	* src/SubsetSuffixArraySearch.cc:
	Refactoring (removed a non-optimization).
	[8fd0504668b4]

	* src/SubsetSuffixArraySearch.cc:
	Made lastal with option -l a bit faster.
	[8b86fcd80c92]

	* src/SubsetSuffixArray.cc, src/SubsetSuffixArraySearch.cc,
	src/makefile:
	Refactoring.
	[fe9d9b819546]

	* test/last-test.out, test/last-test.sh:
	Added some tests for min & max seed length.
	[bc0f1de8dbd3]

	* doc/lastal.txt, doc/tag-seeds.txt, src/LastalArguments.cc,
	src/LastalArguments.hh, src/lastal.cc, test/last-test.out:
	! Changed the meaning of lastal option -l, and added option -L.
	[f92167aee244]

	* src/SubsetSuffixArray.cc, src/SubsetSuffixArray.hh, src/lastal.cc:
	Continued implementing min & max seed length.
	[5aadb69de0c6]

2014-10-29  Martin C. Frith  <Martin C. Frith>

	* src/LastalArguments.cc, test/last-test.out:
	Added C option (if used) to header of lastal output.
	[5fe9efc1364d]

	* src/LastalArguments.cc:
	Refactoring.
	[1a83eb621b97]

	* src/SubsetSuffixArray.cc, src/SubsetSuffixArray.hh, src/lastal.cc:
	Started implementing min & max seed length.
	[a84ce2b7619f]

	* src/SubsetSuffixArray.cc, src/SubsetSuffixArray.hh:
	Refactoring.
	[ec7999011795]

	* doc/maf-convert.txt:
	Tiny doc clarification.
	[c42b75e2afe4]

2014-10-07  Martin C. Frith  <Martin C. Frith>

	* scripts/maf-convert:
	Made maf-convert to tab a bit faster, maybe.
	[f2f4372810c8]

	* scripts/maf-convert:
	Made maf-convert to psl faster.
	[b777fc12e1da]

2014-10-06  Martin C. Frith  <Martin C. Frith>

	* scripts/maf-convert:
	Made maf-convert to tab faster, and allow missing score.
	[a49f450fd21c]

	* scripts/maf-convert:
	Made maf-convert to sam faster.
	[2c3fc2f098ff]

	* scripts/maf-convert:
	Made maf-convert to sam faster.
	[f5ca11b28637]

	* scripts/maf-convert:
	Made maf-convert to sam faster.
	[c5d5add95e5e]

	* scripts/maf-convert:
	Made maf-convert to sam faster.
	[52804495ab96]

2014-10-01  Martin C. Frith  <Martin C. Frith>

	* doc/lastal.txt, src/LastalArguments.cc, src/LastalArguments.hh,
	src/lastal.cc:
	Removed useless -o option from lastal.
	[63b30414bb21]

2014-09-29  Martin C. Frith  <Martin C. Frith>

	* scripts/last-dotplot:
	Made last-dotplot faster for MAF & work with Python 2.4.
	[f5b731ee703e]

2014-09-24  Martin C. Frith  <Martin C. Frith>

	* doc/last-doc.css:
	Made the html docs a bit prettier.
	[e29f2555e674]

	* doc/Makefile, doc/last-postmask.txt, scripts/last-postmask:
	Added last-postmask.
	[aec8ba9a675a]

	* doc/last-map-probs.txt, doc/last-pair-probs.txt, doc/last-
	scripts.txt, doc/maf-convert.txt, doc/maf-cull.txt, examples/last-
	bisulfite-paired.sh, examples/multiMito.sh, scripts/last-dotplot,
	scripts/last-dotplot.py, scripts/last-map-probs, scripts/last-map-
	probs.py, scripts/last-pair-probs, scripts/last-pair-probs.py,
	scripts/maf-convert, scripts/maf-convert.py, scripts/maf-cull,
	scripts/maf-cull.py, scripts/maf-join, scripts/maf-join.py, scripts
	/maf-sort, scripts/maf-sort.sh, scripts/maf-swap, scripts/maf-
	swap.py, test/maf-convert-test.out, test/maf-convert-test.sh:
	Removed .py and .sh suffixes from script names.
	[e707702f53f8]

	* src/lastal.cc, test/last-test.out:
	Replaced CPU time with number of query sequences, in lastal output.
	[738937827432]

	* doc/lastal.txt, src/LastalArguments.cc, test/last-test.out, test
	/last-test.sh:
	Added doc & test for gapless alignment culling.
	[0a95bc0bb188]

	* doc/lastdb.txt, src/CyclicSubsetSeed.cc:
	Added MAM4 seed pattern to lastdb.
	[d73bfbd75aa6]

2014-08-06  Martin C. Frith  <Martin C. Frith>

	* doc/lastal.txt, scripts/last-dotplot.py:
	Doc tweak; made last-dotplot work with PILLOW (thanks: David
	Mathog).
	[4cf8170b3538]

2014-08-01  Martin C. Frith  <Martin C. Frith>

	* src/lastal.cc, src/split/last-split-main.cc:
	Made lastal and last-split check for write errors.
	[e9d7aaff4a79]

2014-07-30  Martin C. Frith  <Martin C. Frith>

	* src/split/last-split-main.cc, src/split/last-split.cc:
	Minor tweaks to last-split's error messages.
	[4694e56112a8]

2014-07-08  Martin C. Frith  <Martin C. Frith>

	* src/LastalArguments.cc, src/LastalArguments.hh,
	src/SegmentPairPot.cc, src/SegmentPairPot.hh, src/lastal.cc:
	Added lastal option to cull gapless alignments (undocumented for
	now).
	[018a076457f9]

	* src/SegmentPairPot.cc, src/SegmentPairPot.hh, src/lastal.cc:
	Minor refactoring.
	[86dbc55eaec0]

2014-07-04  Martin C. Frith  <Martin C. Frith>

	* src/Alignment.cc, src/SegmentPairPot.cc:
	Slightly reduced lastal's memory usage.
	[c11e3db2c2ea]

2014-07-03  Martin C. Frith  <Martin C. Frith>

	* src/split/last-split.cc:
	Slightly reduced last-split's memory usage.
	[f0d31a5b2412]

2014-06-24  Martin C. Frith  <Martin C. Frith>

	* src/split/last-split.cc:
	Reduced memory usage for split alignment.
	[944412f6be6f]

	* examples/multiMito.maf, examples/multiMito.sh, test/bs100.maf, test
	/last-split-test.out, test/maf-convert-test.out:
	Made the tests fit the previous change.
	[7979e7b67072]

	* doc/last-split.txt, doc/last-tutorial.txt,
	src/split/cbrc_split_aligner.cc, src/split/last-split-main.cc,
	src/split/last-split.cc:
	! Changed split alignment, to treat edge alignments the same as
	internal ones.
	[8eed4b74c117]

	* src/lastal.cc:
	Made lastal not quit if it can't read the lastdb version.
	[b31285f777d5]

2014-06-23  Martin C. Frith  <Martin C. Frith>

	* doc/last-split.txt:
	Doc editing.
	[4c475f9f6314]

	* src/split/cbrc_split_aligner.cc:
	Refactoring.
	[709574287d99]

2014-06-19  Martin C. Frith  <Martin C. Frith>

	* src/split/cbrc_split_aligner.cc, src/split/cbrc_split_aligner.hh:
	Refactoring.
	[a41d6f5ea538]

2014-06-16  Martin C. Frith  <Martin C. Frith>

	* src/Alignment.cc, src/Alignment.hh, src/AlignmentWrite.cc,
	src/lastal.cc:
	Reduced lastal's memory usage a bit.
	[3b9e29db94ae]

2014-06-07  Martin C. Frith  <Martin C. Frith>

	* src/split/cbrc_split_aligner.cc, test/last-split-test.out:
	Tweaked last-split's split boundaries: cleaner inversions.
	[173c05590cd8]

	* src/split/cbrc_split_aligner.cc:
	Refactoring.
	[b3c1c5a55726]

2014-05-21  Martin C. Frith  <Martin C. Frith>

	* src/Centroid.cc:
	Fixed abort in probabilistic alignment with unusual score
	parameters.
	[eda0a55ff69f]

2014-05-09  Martin C. Frith  <Martin C. Frith>

	* doc/last-split.txt, src/split/cbrc_split_aligner.cc,
	src/split/cbrc_split_aligner.hh, src/split/last-split.cc:
	Made last-split handle different insertion & deletion costs.
	[a0f8e88d6e5a]

2014-04-28  Martin C. Frith  <Martin C. Frith>

	* examples/last-bisulfite-paired.sh, examples/last-bisulfite.sh,
	makefile, scripts/last-merge-batches.py, src/last-merge-batches.c,
	src/makefile:
	Made last-merge-batches much faster (Python->C).
	[db7d182005fd]

2014-04-24  Martin C. Frith  <Martin C. Frith>

	* src/split/last-split-main.cc:
	Made last-split much faster at reading stdin.
	[c7b94de8fe47]

	* src/AlignmentWrite.cc:
	Made lastal a bit faster (at writing MAF).
	[38f41e158205]

2014-04-23  Martin C. Frith  <Martin C. Frith>

	* src/GappedXdropAligner.cc, src/GappedXdropAligner2qual.cc,
	src/GappedXdropAlignerPssm.cc:
	Made lastal's gapped extension a bit faster.
	[9e008f32e151]

	* src/makefile:
	Updated the makefile.
	[610ed44ebeca]

	* src/split/cbrc_split_aligner.cc:
	Made last-split a bit faster.
	[8f94abc0f885]

	* src/split/cbrc_split_aligner.cc:
	Made last-split a bit faster.
	[516d264fb6d8]

	* src/split/cbrc_unsplit_alignment.cc:
	Made last-split a bit faster.
	[fa11e4f3473e]

	* src/split/cbrc_unsplit_alignment.cc, src/split/last-split.cc:
	Made last-split a bit faster.
	[dcc5cf6ad293]

2014-04-22  Martin C. Frith  <Martin C. Frith>

	* src/split/cbrc_unsplit_alignment.cc:
	Minor refactoring.
	[7736fb59343c]

	* src/split/cbrc_unsplit_alignment.cc:
	Refactoring.
	[3ffa20a193ad]

	* src/split/cbrc_split_aligner.cc,
	src/split/cbrc_unsplit_alignment.cc, test/last-split-test.out, test
	/last-split-test.sh:
	Fixed a recently-introduced bug in last-split.
	[7bb87bb8acdb]

	* src/split/cbrc_int_exponentiator.hh,
	src/split/cbrc_split_aligner.cc, src/split/cbrc_split_aligner.hh:
	Made last-split much faster
	[26a3e7bc882f]

2014-04-21  Martin C. Frith  <Martin C. Frith>

	* src/split/cbrc_split_aligner.cc:
	Made last-split faster.
	[d3519c58d147]

	* src/split/cbrc_unsplit_alignment.cc:
	Made last-split faster.
	[36ead857cb90]

	* src/split/cbrc_unsplit_alignment.cc:
	Made last-split a bit faster.
	[1487e63dfadb]

	* src/split/cbrc_split_aligner.cc,
	src/split/cbrc_unsplit_alignment.cc,
	src/split/cbrc_unsplit_alignment.hh, src/split/last-split.cc:
	Made last-split faster.
	[4794eb9cbff0]

	* src/split/last-split.cc:
	Refactoring.
	[e477a2c9f43a]

	* src/split/cbrc_unsplit_alignment.cc,
	src/split/cbrc_unsplit_alignment.hh, src/split/last-split.cc:
	Refactoring.
	[f4a4d1d05ee2]

2014-04-18  Martin C. Frith  <Martin C. Frith>

	* src/split/cbrc_unsplit_alignment.cc:
	Made last-split a bit faster.
	[a7183daeffcf]

	* src/split/cbrc_unsplit_alignment.cc,
	src/split/cbrc_unsplit_alignment.hh, src/split/last-split.cc:
	Made last-split faster.
	[5be0ed580a4c]

	* src/split/cbrc_unsplit_alignment.cc,
	src/split/cbrc_unsplit_alignment.hh, src/split/last-split.cc:
	Refactoring.
	[da0231b738f0]

	* doc/last-tutorial.txt, src/GappedXdropAlignerInl.hh,
	src/split/cbrc_unsplit_alignment.cc:
	Refactoring & doc update.
	[dfad6bf18d44]

	* src/split/cbrc_unsplit_alignment.cc,
	src/split/cbrc_unsplit_alignment.hh, src/split/last-split.cc:
	Refactoring.
	[a72d722268c9]

	* src/split/last-split.cc:
	Made last-split a bit faster.
	[2bafc09e402c]

2014-04-17  Martin C. Frith  <Martin C. Frith>

	* src/split/cbrc_split_aligner.cc:
	Made last-split a tiny bit faster (maybe).
	[5b21092e607a]

	* src/split/cbrc_split_aligner.cc:
	Made last-split a bit faster (maybe).
	[d5fb6675a221]

	* src/split/cbrc_split_aligner.cc:
	Made last-split a bit faster.
	[5b75f0c179fc]

	* src/split/cbrc_split_aligner.cc:
	Made last-split a bit faster (maybe).
	[edd67e0f6cf0]

	* src/split/cbrc_split_aligner.cc, src/split/cbrc_split_aligner.hh:
	Made last-split faster.
	[5386045403ac]

2014-04-16  Martin C. Frith  <Martin C. Frith>

	* src/split/cbrc_split_aligner.cc, src/split/cbrc_split_aligner.hh:
	Refactoring.
	[c6a6a676f4de]

	* src/split/cbrc_split_aligner.cc:
	Refactoring.
	[56df65163a97]

	* src/split/cbrc_unsplit_alignment.cc:
	Made last-split faster.
	[67213fcafb6c]

	* src/split/cbrc_unsplit_alignment.cc:
	Made last-split a bit faster.
	[51453d3f661f]

	* src/split/cbrc_unsplit_alignment.cc:
	Made last-split faster.
	[ddcd63616589]

2014-04-15  Martin C. Frith  <Martin C. Frith>

	* src/split/cbrc_unsplit_alignment.cc:
	Made last-split faster.
	[ec619deb1d67]

	* src/split/cbrc_split_aligner.cc,
	src/split/cbrc_unsplit_alignment.hh, src/split/last-split.cc:
	Made last-split a bit faster.
	[8e8fe7f65b39]

	* src/split/cbrc_unsplit_alignment.cc,
	src/split/cbrc_unsplit_alignment.hh:
	Made last-split a bit faster.
	[adbf4b9d6e8a]

2014-03-07  Martin C. Frith  <Martin C. Frith>

	* doc/maf-convert.txt:
	Fixed a doc typo.
	[825cd70c55e2]

2014-02-17  Martin C. Frith  <Martin C. Frith>

	* scripts/maf-convert.py:
	Made maf-convert a bit faster.
	[d6509e5bac46]

	* scripts/maf-convert.py:
	Made maf-convert a bit faster.
	[28dea51811fc]

	* scripts/maf-convert.py:
	Made maf-convert a bit faster.
	[ad28a1039625]

	* test/last-test.sh, test/maf-convert-test.out, test/maf-convert-
	test.sh:
	Added tests for maf-convert.
	[feda1395a162]

	* doc/maf-convert.txt, scripts/maf-convert.py:
	Added maf-convert noheader option.
	[0870b0386ca2]

2014-02-12  Martin C. Frith  <Martin C. Frith>

	* src/MultiSequence.hh, src/SubsetSuffixArray.cc, src/lastal.cc,
	src/lastdb.cc:
	Bugfix: lastal rejected volumes of size 2^32-1.
	[65756fdad0a7]

2014-02-07  Martin C. Frith  <Martin C. Frith>

	* doc/last-map-probs.txt, scripts/last-map-probs.py:
	Simplified last-map-probs usage a bit.
	[7d0e5a283d3c]

	* doc/last-tutorial.txt, examples/bisulfite_f.mat,
	examples/bisulfite_f.seed, examples/bisulfite_r.mat,
	examples/bisulfite_r.seed:
	Doc cleanup.
	[2e29cd38c8e9]

	* src/LastalArguments.cc, src/lastal.cc, test/last-test.sh:
	Default to blosum80 instead of blosum62 for DNA-protein alignment.
	[ef08e7127c60]

2014-02-06  Martin C. Frith  <Martin C. Frith>

	* doc/bisulfite.txt, examples/last-bisulfite-paired.sh, examples/last-
	bisulfite.sh, src/LastdbArguments.cc, src/ScoreMatrix.cc, test/last-
	test.sh:
	Simplified the bisulfite usage a bit.
	[0e9a63996bd9]

	* doc/last-tutorial.txt, doc/lastal.txt, doc/lastdb.txt,
	src/LastalArguments.cc, src/LastdbArguments.cc,
	src/LastexArguments.cc:
	Documented named seeds and score matrices.
	[ab0a83566fca]

2014-02-05  Martin C. Frith  <Martin C. Frith>

	* doc/bisulfite.txt, examples/last-bisulfite-paired.sh, examples/last-
	bisulfite.sh:
	Simplified the bisulfite recipes.
	[fb32a41126c9]

	* test/last-test.out, test/last-test.sh:
	Added a test.
	[165cceb3826b]

	* test/last-test.out, test/last-test.sh:
	Added a test.
	[1956fc0d56fa]

	* test/bs100.fastq, test/bs100.maf, test/hg19-M.fa, test/last-test.sh:
	Added a test for bisulfite.
	[a1a7f9fb7ff0]

	* src/ScoreMatrix.cc, src/ScoreMatrix.hh, src/lastal.cc,
	src/lastex.cc:
	Added named score matrices (undocumented).
	[99937f273f83]

	* src/CyclicSubsetSeed.cc, src/CyclicSubsetSeed.hh, src/lastdb.cc:
	Added named seeds (undocumented).
	[1443fafa5297]

	* src/CyclicSubsetSeed.cc, src/CyclicSubsetSeed.hh, src/lastdb.cc:
	Refactoring.
	[54354c8a06e8]

2014-02-04  Martin C. Frith  <Martin C. Frith>

	* src/CyclicSubsetSeed.cc, src/CyclicSubsetSeed.hh,
	src/LastdbArguments.cc:
	Refactoring.
	[6ba52407257e]

	* src/CyclicSubsetSeed.cc, src/CyclicSubsetSeed.hh, src/lastdb.cc:
	Refactoring.
	[ae761664c223]

	* src/CyclicSubsetSeed.cc:
	Refactoring.
	[35375cde644f]

	* src/CyclicSubsetSeed.cc, src/CyclicSubsetSeed.hh, src/lastdb.cc:
	Refactoring.
	[ed695aad7193]

	* src/LastdbArguments.cc, src/LastdbArguments.hh, src/lastdb.cc:
	Refactoring.
	[a33b79807536]

	* src/CyclicSubsetSeed.cc, src/CyclicSubsetSeed.hh, src/lastdb.cc:
	Refactoring.
	[a079809dc433]

2014-01-15  Martin C. Frith  <Martin C. Frith>

	* src/Alignment.cc:
	Bugfix: lastal aborted with -T1 and subset seeds (e.g. bisulfite).
	[bdcb6a1794b0]

2013-12-07  Martin C. Frith  <Martin C. Frith>

	* src/Alignment.cc:
	Bugfix: frameshifting alignment was buggy since v389 (thanks: Ruth
	Miller).
	[08c9e9dd391a]

2013-12-05  Martin C. Frith  <Martin C. Frith>

	* src/MultiSequenceQual.cc, src/split/cbrc_split_aligner.cc:
	Check for bad fastq quality data more carefully (thanks: Darek
	Kedra).
	[648da3053003]

	* scripts/last-dotplot.py:
	Tweaked some dotplot parameters.
	[f05b39763e60]

2013-12-02  Martin C. Frith  <Martin C. Frith>

	* src/Alignment.cc, src/Alignment.hh, src/AlignmentWrite.cc,
	src/GeneticCode.cc, src/GeneticCode.hh:
	Refactoring.
	[666c5b00ff85]

	* src/AlignmentWrite.cc:
	Minor refactoring.
	[61ab2a981d1f]

	* src/Alignment.cc, src/Alignment.hh, src/AlignmentPot.hh,
	src/AlignmentWrite.cc, src/lastal.cc:
	Minor refactoring.
	[74291df45c64]

	* src/split/cbrc_split_aligner.cc:
	Made cis-spliced alignment startup a bit faster.
	[8cb17de3471e]

	* src/split/cbrc_split_aligner.cc, src/split/cbrc_split_aligner.hh:
	Made spliced alignment faster.
	[657dbbbaff7b]

2013-11-30  Martin C. Frith  <Martin C. Frith>

	* src/split/cbrc_split_aligner.cc:
	Made cis-spliced alignment a tiny bit faster.
	[6d3e5500a3f6]

	* src/split/cbrc_split_aligner.cc:
	Made cis-spliced alignment a bit faster.
	[6b5f43d21d4e]

	* src/split/cbrc_split_aligner.cc, src/split/cbrc_split_aligner.hh:
	Made cis-spliced alignment much faster.
	[4fd9db8ed8f9]

2013-11-29  Martin C. Frith  <Martin C. Frith>

	* src/split/cbrc_split_aligner.cc:
	Bugfix: last-split aborted on fastq-illumina data (thanks: Anish
	Shrestha).
	[807d93eb9398]

	* src/split/cbrc_split_aligner.cc, src/split/cbrc_split_aligner.hh:
	Made cis-spliced alignment a bit faster.
	[ff3e21fde5e9]

2013-11-28  Martin C. Frith  <Martin C. Frith>

	* src/split/cbrc_split_aligner.cc, src/split/cbrc_split_aligner.hh,
	test/last-split-test.out:
	Made cis-spliced alignment faster (which rarely changes the
	probabilities).
	[69ae9c1da2bc]

	* src/split/cbrc_split_aligner.cc, src/split/cbrc_split_aligner.hh,
	test/last-split-test.out:
	Made spliced alignment faster (which changes the probabilities a
	bit).
	[ab57f7a0bf07]

2013-11-25  Martin C. Frith  <Martin C. Frith>

	* src/makefile:
	Made re-compilation faster.
	[146da0983d56]

2013-11-11  Martin C. Frith  <Martin C. Frith>

	* doc/last.txt, src/LastalArguments.cc, src/LastdbArguments.cc,
	src/LastexArguments.cc, src/qualityScoreUtil.hh:
	Changed the email address.
	[c8b41899f04e]

	* src/qualityScoreUtil.hh, src/split/cbrc_split_aligner.cc:
	Fixed crash with fastq and high mismatch cost (thanks: Dave
	duVerle).
	[6524c84d5010]

	* doc/last-split.txt:
	Added poly-A tail FAQ to the last-split doc.
	[72d47af7ac19]

2013-11-09  Martin C. Frith  <Martin C. Frith>

	* doc/bisulfite.txt, examples/last-bisulfite-paired.sh, examples/last-
	bisulfite.sh, examples/lastal-bisulfite-paired.sh:
	Tried to simplify bisulfite alignment.
	[3e54ea29d396]

	* doc/last-scripts.txt, scripts/last-reduce-alignments.sh, scripts
	/last-remove-dominated.py:
	Removed last-reduce-alignments and last-remove-dominated.
	[4de08a642180]

	* doc/last-tutorial.txt:
	Recommend last-split for genome comparison in the tutorial.
	[d94ccff38eb2]

	* examples/multiMito.maf, examples/multiMito.sh, test/last-test.sh:
	Use last-split instead of last-reduce-alignments in the multiMito
	example.
	[83b7885e7289]

	* makefile:
	Removed the last-split executable from the zip-file.
	[56105d01281d]

2013-11-08  Martin C. Frith  <Martin C. Frith>

	* src/split/cbrc_split_aligner.cc, src/split/cbrc_split_aligner.hh,
	src/split/last-split.cc:
	Made last-split support fastq-illumina data.
	[0170f51e256c]

2013-11-07  Martin C. Frith  <Martin C. Frith>

	* src/LastalArguments.cc, test/last-test.out:
	Added T and Q parameters to the header of the lastal output.
	[bf2486ffc14c]

	* doc/last-split.txt, src/split/cbrc_unsplit_alignment.cc, src/split
	/last-split.cc:
	Made last-split compatible with the bisulfite recipe.
	[13dd8ce7563d]

2013-11-05  Martin C. Frith  <Martin C. Frith>

	* doc/last-map-probs.txt, doc/last-split.txt, doc/last-tutorial.txt,
	makefile, scripts/parallel-fasta, scripts/parallel-fastq:
	Added parallel-fasta and parallel-fastq.
	[12b5485bf653]

	* doc/last-tutorial.txt:
	Recommending last-split instead of last-map-probs in the main
	tutorial.
	[4d5149f35e8c]

	* doc/bisulfite.txt, doc/last-map-probs.txt, doc/last-split.txt, doc
	/last-tutorial.txt, doc/lastal.txt, doc/lastdb.txt,
	src/LastalArguments.cc, src/LastdbArguments.cc, src/lastal.cc,
	src/lastdb.cc:
	Made lastdb and lastal read stdin when given no sequence file-names.
	[6ed7b14969a5]

2013-10-15  Martin C. Frith  <Martin C. Frith>

	* src/split/last-split.cc, test/last-split-test.out, test/last-split-
	test.sh:
	Print the last-split RNA/intron strand option in the header.
	[ee65c63ae8b6]

	* doc/last-split.txt, src/split/cbrc_split_aligner.cc,
	src/split/cbrc_split_aligner.hh, src/split/last-split-main.cc,
	src/split/last-split.cc, src/split/last-split.hh, test/last-split-
	test.out:
	Added last-split option to specify RNA/intron strand.
	[f1204fad2cd7]

	* src/split/cbrc_split_aligner.cc, src/split/cbrc_split_aligner.hh,
	src/split/last-split.cc:
	Refactoring
	[430afce5f00b]

2013-10-04  Martin C. Frith  <Martin C. Frith>

	* makefile:
	Added last-split to "make install"
	[d6323081a217]

	* doc/Makefile, doc/last-split-probs.txt, doc/last-split.txt, scripts
	/last-split-probs.py, src/makefile, src/split/cbrc_linalg.cc,
	src/split/cbrc_linalg.hh, src/split/cbrc_split_aligner.cc,
	src/split/cbrc_split_aligner.hh,
	src/split/cbrc_unsplit_alignment.cc,
	src/split/cbrc_unsplit_alignment.hh, src/split/last-split-main.cc,
	src/split/last-split.cc, src/split/last-split.hh,
	test/SRR359290-1k.maf, test/last-split-test.out, test/last-split-
	test.sh:
	Replaced last-split-probs with last-split !
	[bc5801666fb2]

2013-10-02  Martin C. Frith  <Martin C. Frith>

	* examples/lastal-bisulfite-paired.sh, src/Alphabet.hh,
	src/Centroid.hh:
	Very minor code tweaks
	[7add737275da]

2013-09-02  Martin C. Frith  <Martin C. Frith>

	* test/last-test.out, test/last-test.sh:
	Added a test.
	[b2417b896e40]

2013-09-01  Martin C. Frith  <Martin C. Frith>

	* src/Centroid.cc, src/Centroid.hh:
	Made the probabilistic dynamic-programming similar to the non-
	probabilistic DP.
	[54f9d38e78a8]

	* src/Centroid.cc:
	Fixed some code that's probably never used anyway.
	[ecf35f1babbb]

	* src/Centroid.cc, src/Centroid.hh:
	Simplified the probabilistic alignment with a cunning trick.
	[66169fb0dc4b]

2013-08-31  Martin C. Frith  <Martin C. Frith>

	* src/Centroid.cc, test/last-test.out, test/last-test.sh:
	Refactoring & added a test.
	[b14f98bb0aaf]

2013-08-29  Martin C. Frith  <Martin C. Frith>

	* src/Centroid.cc:
	Very minor refactoring.
	[da5103b17109]

	* src/Centroid.cc:
	Very minor refactoring.
	[e19ac83cdf39]

	* src/Centroid.cc:
	Refactoring.
	[4afc604780f8]

	* src/Centroid.cc:
	Refactoring.
	[045d538073b5]

	* src/Centroid.cc, src/Centroid.hh:
	Refactoring.
	[a4c602f1974f]

	* src/Centroid.cc:
	Refactoring.
	[28b33aa17b79]

	* src/Centroid.cc:
	Refactoring.
	[76d3f93bab3c]

	* src/Centroid.cc:
	Refactoring (just renamed a variable).
	[308b26210a2a]

	* src/Alignment.cc, src/Alignment.hh:
	Refactoring.
	[9a8f96fcc9e1]

	* src/Centroid.cc, src/Centroid.hh:
	Increased robustness to integer overflow (maybe).
	[ccc85569d01c]

	* src/Centroid.cc, src/Centroid.hh:
	Refactoring.
	[4e33c00a4a1b]

	* src/Centroid.cc, src/Centroid.hh:
	Refactoring.
	[d6c67ba4c15b]

	* src/Centroid.cc:
	Refactoring.
	[8c5ba2c1fcd5]

2013-08-28  Martin C. Frith  <Martin C. Frith>

	* src/Centroid.cc:
	Refactoring.
	[d598fe33632b]

	* src/Centroid.cc:
	Refactoring.
	[7817575bf345]

	* src/Centroid.cc:
	Refactoring.
	[8d6e98549602]

	* src/Centroid.cc:
	Refactoring.
	[3e6bfbaccc08]

	* src/Centroid.cc, src/Centroid.hh, src/lastal.cc:
	Removed trailing whitespace.
	[df07ac99d269]

	* src/Centroid.cc:
	Refactoring.
	[6482c7a4300a]

	* src/Centroid.cc:
	Refactoring.
	[32751b1d8a1f]

	* src/Alignment.cc, src/Centroid.cc, src/Centroid.hh:
	Added probabilistic overlap alignment (thanks: Toshiyuki Sato).
	[a6c02431602e]

	* src/Centroid.cc:
	Minor refactoring.
	[7e46c96be97f]

2013-08-26  Martin C. Frith  <Martin C. Frith>

	* doc/lastal.txt, test/last-test.out, test/last-test.sh:
	Added doc & test for overlap alignment.
	[62ec547050d0]

	* src/Alignment.cc, src/Alignment.hh, src/LastalArguments.cc,
	src/LastalArguments.hh, src/lastal.cc:
	Added overlap alignment! (Thanks: Toshiyuki Sato)
	[2ae0f4be8ea4]

	* src/Alignment.cc, src/GappedXdropAligner.cc,
	src/GappedXdropAligner.hh, src/GappedXdropAligner2qual.cc,
	src/GappedXdropAlignerInl.hh, src/GappedXdropAlignerPssm.cc:
	Started to add overlap alignment (thanks: Toshiyuki Sato).
	[16d72fa5320b]

	* src/Alignment.cc:
	Minor refactoring.
	[405438cd37ea]

2013-08-25  Martin C. Frith  <Martin C. Frith>

	* src/AlignmentWrite.cc:
	Generalized tabular-output-writing so it handles alignments ending
	with gaps.
	[7692523417d0]

	* src/GappedXdropAligner.cc:
	Generalized the traceback so it handles alignments ending with gaps.
	[4f46d830e949]

2013-08-23  Martin C. Frith  <Martin C. Frith>

	* doc/bisulfite.txt, examples/lastal-bisulfite-paired.sh:
	Added a script for aligning paired bisulfite reads (in parallel).
	[660ff05b7f0e]

	* scripts/maf-convert.py:
	Tweaked maf-convert's BLAST output (thanks: Nick Loman).
	[b93b23a4d23d]

	* src/Alignment.cc, src/Centroid.cc, src/LastalArguments.cc:
	Allow different ins & del costs in probabilistic alignment (thanks:
	T Sato).
	[69107a55e7ab]

2013-07-26  Martin C. Frith  <Martin C. Frith>

	* examples/hoxd70.mat, test/last-test.out:
	Added "N" scores to hoxd70.
	[00b0426f4a4d]

2013-07-25  Martin C. Frith  <Martin C. Frith>

	* examples/multiMito.maf, src/LastalArguments.cc, test/last-test.out:
	! Changed the default for lastal "-x": affects max gap size & run-
	time.
	[a3aae9fc866a]

2013-07-16  Martin C. Frith  <Martin C. Frith>

	* doc/lastdb.txt, test/last-test.out, test/last-test.sh:
	Added doc & tests for recent changes.
	[46bdfb358572]

	* src/CyclicSubsetSeed.cc, src/LastdbArguments.cc:
	Allow comma-separated seed patterns; check for empty seed patterns.
	[bea2065529ce]

	* src/CyclicSubsetSeed.cc, src/CyclicSubsetSeed.hh,
	src/LastdbArguments.cc, src/LastdbArguments.hh, src/lastdb.cc:
	Easy input of transition-constrained seed patterns (undocumented).
	[2ac64facdc4c]

	* src/lastal.cc:
	Made lastal read lastdb files more strictly.
	[38003ee6a77c]

	* src/LastalArguments.cc, src/LastalArguments.hh, src/lastal.cc:
	Enabled multiple seed patterns in lastal.
	[882fd4b4e364]

	* src/lastdb.cc:
	Enabled multiple seed patterns in lastdb.
	[4649149270c5]

	* src/SubsetSuffixArray.cc, src/SubsetSuffixArray.hh, src/lastdb.cc:
	Continued to enable multiple seed patterns...
	[ba7f7354d1eb]

	* src/lastdb.cc:
	Continued to enable multiple seed patterns...
	[c0c62851c1e3]

	* src/lastdb.cc:
	Continued to enable multiple seed patterns.
	[b757a18867f2]

	* src/LastdbArguments.cc, src/LastdbArguments.hh, src/lastdb.cc:
	Started to enable multiple seed patterns.
	[60b4d3648b6f]

	* src/SubsetSuffixArray.cc, src/SubsetSuffixArray.hh, src/lastdb.cc:
	Fixed apparent lastdb overflow bug with huge sequence data and w>1.
	[593a8f860a3f]

2013-07-15  Martin C. Frith  <Martin C. Frith>

	* doc/lastdb.txt, src/SubsetSuffixArray.cc, src/SubsetSuffixArray.hh,
	src/lastdb.cc:
	! Changed the behaviour of lastdb -s (volume size): simpler &
	cruder.
	[77d6c2b29ecd]

2013-07-14  Martin C. Frith  <Martin C. Frith>

	* src/CyclicSubsetSeed.cc, src/SubsetSuffixArray.cc, src/lastal.cc:
	Added some error-checking when reading files.
	[ae38cba11e0b]

	* src/SubsetSuffixArray.cc, src/SubsetSuffixArray.hh, src/lastal.cc,
	src/lastdb.cc:
	! Changed lastdb file format: lastal will refuse to read old lastdb
	files.
	[77648600d92e]

2013-07-13  Martin C. Frith  <Martin C. Frith>

	* src/SubsetSuffixArray.cc, src/SubsetSuffixArray.hh, src/lastal.cc:
	Made the suffix-array-reading code more self-contained.
	[89da6a07f3bf]

	* src/SubsetSuffixArray.cc, src/SubsetSuffixArray.hh, src/lastdb.cc:
	Made the suffix-array-writing code more self-contained.
	[e85e91f0dbd1]

	* src/CyclicSubsetSeed.cc, src/CyclicSubsetSeed.hh:
	Made it possible to clear & re-read a seed pattern.
	[199611bc4916]

	* src/CyclicSubsetSeed.hh, src/SubsetSuffixArray.hh,
	src/SubsetSuffixArraySort.cc, src/lastdb.cc:
	Refactor: just moved a typedef.
	[4c08ae190646]

2013-07-09  Martin C. Frith  <Martin C. Frith>

	* src/SubsetSuffixArray.cc, src/SubsetSuffixArray.hh,
	src/SubsetSuffixArraySort.cc, src/lastal.cc, src/lastdb.cc:
	Refactor: made the subset seed a member of the subset suffix array.
	[054e61cc84f3]

2013-07-03  Martin C. Frith  <Martin C. Frith>

	* doc/lastal.txt, doc/lastdb.txt, test/last-test.out, test/last-
	test.sh:
	Added test & doc for lastdb -i, and running lastal on single
	volumes.
	[4265eaec011c]

2013-06-26  Martin C. Frith  <Martin C. Frith>

	* src/LastalArguments.cc, src/LastalArguments.hh, src/lastal.cc, test
	/last-test.out:
	Set the default for lastal "d" separately for each lastdb volume.
	[d567aaece7a3]

2013-06-25  Martin C. Frith  <Martin C. Frith>

	* src/lastdb.cc:
	Made lastdb write 1-volume databases in a simpler set of files.
	[08809771f21b]

	* src/lastal.cc:
	Made lastal able to read one volume (undocumented).
	[a839387881e0]

	* src/lastal.cc:
	Made lastal read the lastdb files a bit more strictly.
	[c1ae4b660da3]

2013-06-24  Martin C. Frith  <Martin C. Frith>

	* src/lastdb.cc:
	Made lastdb write more info in inner prj files (not used yet).
	[5bc0cb31f63f]

2013-06-21  Martin C. Frith  <Martin C. Frith>

	* doc/lastdb.txt, src/LastdbArguments.cc, src/LastdbArguments.hh,
	src/SubsetSuffixArray.hh, src/SubsetSuffixArraySort.cc,
	src/lastal.cc, src/lastdb.cc:
	Added lastdb -i option, to make it faster by incomplete sorting.
	[88a090cfcfda]

	* src/LastalArguments.cc:
	Just changed some help text.
	[58dcba2aa9c9]

2013-06-11  Martin C. Frith  <Martin C. Frith>

	* doc/maf-convert.txt, scripts/maf-convert.py:
	Made maf-convert accept zero or more file names.
	[21ec283344a0]

	* doc/FAQ.txt:
	Added %identity FAQ.
	[5e10487d7fc1]

2013-06-10  Martin C. Frith  <Martin C. Frith>

	* src/gaplessPssmXdrop.cc, src/gaplessTwoQualityXdrop.cc,
	src/gaplessXdrop.cc:
	Made lastal a bit faster (gapless extension phase).
	[d073de15e8ad]

	* src/makefile:
	Get the version more robustly.
	[f39b98c2fb79]

2013-05-23  Martin C. Frith  <Martin C. Frith>

	* .hgignore, makefile, src/makefile:
	Changed version control from subversion to mercurial.
	[d11b0382e04d]

2013-04-22  Martin C. Frith  <Martin C. Frith>

	* doc/maf-convert.txt, scripts/maf-convert.py:
	Added maf-convert dictfile option.
	[064a55a7225f]

	* doc/maf-convert.txt, scripts/maf-convert.py:
	Added maf-convert readgroup option.
	[d4f51fc56453]

2013-04-19  Martin C. Frith  <Martin C. Frith>

	* doc/FAQ.txt, doc/maf-convert.txt, scripts/maf-convert.py:
	Made maf-convert's sam output more acceptable to GATK/picard.
	[617c9ab84534]

2013-04-16  Martin C. Frith  <Martin C. Frith>

	* scripts/maf-convert.py:
	Made maf-convert interpret "/1" and "/2" as paired sequences
	(undocumented).
	[d44b9010b0eb]

	* doc/last-pair-probs.txt, scripts/last-pair-probs.py:
	Made last-pair-probs append "/1" and "/2" to query names, if
	missing.
	[f0739cfef39d]

	* doc/bisulfite.txt:
	! Documentation bugfix: the bisulfite paired-end recipe was stupidly
	wrong.
	[a8d169b27919]

2013-04-15  Martin C. Frith  <Martin C. Frith>

	* doc/FAQ.txt, doc/Makefile, doc/last-pair-probs.txt, doc/maf-
	convert.txt:
	Some doc updates.
	[96409edb2a36]

	* scripts/last-split-probs.py:
	Just added a comment
	[67c1dc5e4215]

2013-03-05  Martin C. Frith  <Martin C. Frith>

	* src/lastal.cc, test/last-test.out:
	Added a batch marker at start of lastal outputs, so they can be
	concatenated.
	[eb44b445d03d]

	* doc/FAQ.txt, doc/last-tutorial.txt:
	Added GNU parallel recipes to last-tutorial.
	[bcf912c0eb1e]

	* src/lastal.cc:
	Added some checking and error messages for bad input.
	[f90a5b82472d]

2013-03-01  Martin C. Frith  <Martin C. Frith>

	* doc/bisulfite.txt, doc/last-map-probs.txt, doc/last-pair-probs.txt,
	doc/last-split-probs.txt, doc/last-tutorial.txt,
	src/LastalArguments.cc, src/LastalArguments.hh, src/lastal.cc, test
	/last-test.out:
	! Changed the default setting of lastal option -d.
	[c34146ded8ab]

2013-02-12  Martin C. Frith  <Martin C. Frith>

	* doc/last-map-probs.txt, doc/last-tutorial.txt:
	Doc updates.
	[973270605980]

2013-02-11  Martin C. Frith  <Martin C. Frith>

	* scripts/last-dotplot.py:
	Made last-dotplot faster.
	[461c012731fc]

	* doc/last-scripts.txt, scripts/last-dotplot.py:
	Made last-dotplot able to read MAF format.
	[935227c035b0]

2013-02-06  Martin C. Frith  <Martin C. Frith>

	* src/fileMap.cc:
	Made the mmap error messages more detailed.
	[1ccb6e25d4bf]

2013-02-04  Martin C. Frith  <Martin C. Frith>

	* doc/Makefile, doc/last.txt, doc/maf-cull.txt:
	Minor doc edits.
	[dc1fab3f2f9e]

	* doc/last-tutorial.txt, doc/last.txt:
	Doc updates.
	[cbe2e24fbd9f]

2013-02-03  Martin C. Frith  <Martin C. Frith>

	* doc/lastal.txt, doc/tag-seeds.txt, src/LastalArguments.cc,
	src/SubsetSuffixArray.cc, src/SubsetSuffixArray.hh, test/last-
	test.out:
	! Changed the interaction between lastal -m and -l from AND to OR.
	[cd3fb1f3626f]

2013-02-01  Martin C. Frith  <Martin C. Frith>

	* src/LastalArguments.cc, src/TwoQualityScoreMatrix.cc,
	src/TwoQualityScoreMatrix.hh, test/last-test.out:
	Made lastal -n default to -m instead of inf. This has no effect
	(yet).
	[9ddd72f3ea16]

2012-12-21  Martin C. Frith  <Martin C. Frith>

	* src/GappedXdropAligner2qual.cc, test/last-test.out, test/last-
	test.sh, test/sd-ccs-100.fq:
	! Bugfix: fastq-v-fastq alignment was using wrong query quality
	data.
	[0efe0e4ea326]

2012-11-14  Martin C. Frith  <Martin C. Frith>

	* test/last-test.out, test/last-test.sh:
	Added a test of gapless alignment.
	[503f5e685bb6]

2012-11-13  Martin C. Frith  <Martin C. Frith>

	* doc/lastal.txt, src/Alignment.cc, src/Alignment.hh,
	src/AlignmentWrite.cc, src/Centroid.cc, src/Centroid.hh, test/last-
	test.out:
	Added fullScore to lastal output.
	[f20af15efa11]

2012-10-29  Martin C. Frith  <Martin C. Frith>

	* src/Alignment.cc, src/Alignment.hh, src/AlignmentWrite.cc,
	src/LastalArguments.cc, src/lastal.cc:
	Added lastal option to write expected counts (not documented yet).
	[20bee444cd56]

2012-10-23  Martin C. Frith  <Martin C. Frith>

	* doc/Makefile:
	Tried harder to make the HTML documents in a more portable way.
	[b5b0991bf36c]

	* doc/Makefile:
	Tried to make the HTML documents in a more portable way.
	[a0a0b03ed406]

	* doc/last-tutorial.txt:
	Minor doc edits.
	[87b6bb724860]

2012-10-22  Martin C. Frith  <Martin C. Frith>

	* README.txt, doc/Makefile, doc/last.txt:
	Just edited some documentation.
	[cd270cd875d5]

	* doc/last.txt:
	Started moving useful info from the README to the doc directory.
	[9611ae3af223]

2012-10-21  Martin C. Frith  <Martin C. Frith>

	* doc/Makefile, doc/last-doc.css, makefile:
	Added HTML versions of some documents.
	[d012f1d2a8b9]

	* doc/last-pair-probs.txt:
	RST-ified last-pair-probs.txt, and added a GNU parallel recipe.
	[09cd862fa41f]

	* doc/bisulfite.txt, doc/last-map-probs.txt, doc/last-split-probs.txt:
	RST-ified some more documents.
	[d7a26503b802]

	* doc/last-tutorial.txt:
	RST-ified last-tutorial.txt.
	[dca0a1daa165]

	* README.txt, doc/lastal.txt:
	Slight documentation edits.
	[42bc0c18af3c]

	* src/CA_code/nrutil.c:
	Just fixed a compiler warning.
	[c7261447b95a]

2012-10-09  Martin C. Frith  <Martin C. Frith>

	* scripts/last-remove-dominated.py:
	Bugfix: made last-remove-dominated (and hence last-reduce-
	alignments) accept output from lastal version >= r238.
	[a6e9eab3e56d]

2012-08-16  Martin C. Frith  <Martin C. Frith>

	* makefile:
	Minor refactoring of the makefile.
	[70e77489aa2f]

2012-08-05  Martin C. Frith  <Martin C. Frith>

	* src/Alphabet.hh, src/lastal.cc, src/lastex.cc:
	Default to Blosum62 for any alphabet that starts with
	ACDEFGHIKLMNPQRSTVWY.
	[a05f5b5bde91]

2012-07-31  Martin C. Frith  <Martin C. Frith>

	* doc/bisulfite.txt, doc/maf-convert.txt:
	Clarified paired-end bisulfite data, and maf-convert -d, in the
	docs.
	[eb9e8dc97f70]

2012-07-09  Martin C. Frith  <Martin C. Frith>

	* scripts/last-map-probs.py:
	! Made last-map-probs faster, and slightly changed (shortened) its
	output.
	[f8789f48456a]

	* scripts/last-map-probs.py:
	Minor refactoring.
	[f9afa432bcc7]

	* scripts/last-map-probs.py:
	Made last-map-probs a tiny bit faster, maybe.
	[fc467f99add1]

	* scripts/last-map-probs.py:
	Made last-map-probs a bit more efficient, maybe.
	[ce5f011254cf]

	* scripts/last-map-probs.py:
	Made last-map-probs a bit faster.
	[61cb64703481]

	* scripts/last-map-probs.py:
	Made last-map-probs a bit faster.
	[f74edcbcec6b]

2012-07-08  Martin C. Frith  <Martin C. Frith>

	* src/LastalArguments.cc, src/LastalArguments.hh, src/lastal.cc, test
	/last-test.out:
	! Changed lastal's default batch size: this can make it faster, but
	it changes the output order.
	[5dbf6b4f872b]

	* doc/bisulfite.txt, doc/last-tutorial.txt, doc/lastdb.txt:
	Improved the docs for bisulfite data, and for running lastdb on huge
	datasets.
	[b03773ef0133]

2012-07-06  Martin C. Frith  <Martin C. Frith>

	* test/last-test.out:
	Updated the test CPU times for the new development computer.
	[f5b7f9ab1725]

	* doc/lastal.txt, src/LastalArguments.cc, src/LastalArguments.hh,
	src/lastal.cc, test/last-test.out:
	Enabled different costs for insertions and deletions.
	[48ad769f870d]

	* src/Alignment.cc, src/Centroid.cc, src/GeneralizedAffineGapCosts.cc,
	src/GeneralizedAffineGapCosts.hh, src/lastal.cc:
	Continued to implement different costs for insertions and deletions.
	[dde4fc49ec9d]

	* src/Alignment.cc, src/GappedXdropAligner.cc,
	src/GappedXdropAligner.hh, src/GappedXdropAligner2qual.cc,
	src/GappedXdropAlignerPssm.cc:
	Started to implement different costs for insertions and deletions.
	[bc1a7edd8235]

2012-06-25  Martin C. Frith  <Martin C. Frith>

	* scripts/last-pair-probs.py:
	Made last-pair-probs a bit faster.
	[f7c78352421f]

2012-06-20  Martin C. Frith  <Martin C. Frith>

	* src/Centroid.cc:
	Minor refactoring.
	[4fcb65616f40]

2012-06-13  Martin C. Frith  <Martin C. Frith>

	* src/GappedXdropAligner.cc, src/GappedXdropAligner3frame.cc, test
	/last-test.out, test/last-test.sh:
	! Bugfix: generalized affine gaps were wrong since version 192.
	[e5bd7a6d664f]

2012-06-12  Martin C. Frith  <Martin C. Frith>

	* src/Centroid.cc, src/Centroid.hh, src/GappedXdropAligner.hh:
	Refactored some of the Centroid code a bit.
	[33297f4d5ffa]

	* src/Centroid.cc, src/Centroid.hh, src/GappedXdropAligner.hh:
	Made probabilistic alignment (lastal j>3) much faster (thanks:
	Toshiyuki Sato).
	[dc09cd9a5340]

2012-06-01  Martin C. Frith  <Martin C. Frith>

	* doc/last-pair-probs.txt:
	Enhanced the last-pair-probs doc.
	[6bd9a1ff7cf2]

2012-05-29  Martin C. Frith  <Martin C. Frith>

	* doc/last-pair-probs.txt, scripts/last-pair-probs.py:
	Allow negative distances in last-pair-probs, and update its doc.
	[174c23386df9]

	* scripts/last-pair-probs.py:
	Made last-pair-probs a bit faster.
	[3a4ef7b226cb]

	* scripts/last-pair-probs.py:
	Added last-pair-probs option to estimate the distribution of
	distances only.
	[143cd098c89d]

	* scripts/last-pair-probs.py:
	! Slightly changed the usage of floating point in last-pair-probs.
	[9069ef23d91e]

	* scripts/last-pair-probs.py:
	Edited some last-pair-probs help messages.
	[59dd7dc8f1ee]

	* scripts/last-pair-probs.py:
	Made last-pair-probs a bit faster.
	[38bcbfd05c0e]

	* scripts/last-pair-probs.py:
	! Made last-pair-probs read by batches instead of sorting.
	[97bcb3f0a424]

2012-05-28  Martin C. Frith  <Martin C. Frith>

	* scripts/last-pair-probs.py:
	Minor refactoring.
	[b9ec919221a4]

	* scripts/last-pair-probs.py:
	Refactored some code in last-pair-probs.
	[7d3009252704]

	* scripts/last-pair-probs.py:
	Made last-pair-probs skip its first pass if both fraglen and sdev
	are set.
	[e1ca1c18be32]

	* scripts/last-pair-probs.py:
	Made last-pair-probs a bit faster (but require header data to be at
	the top).
	[f9bce1362955]

	* scripts/last-pair-probs.py:
	Bugfix: if the final MAF block in a file given to last-pair-probs
	did not end in a blank line, the output MAF blocks were not always
	separated by blank lines.

	Improved a last-pair-probs error message.
	[fb2c9c9e2f81]

	* scripts/last-pair-probs.py:
	Made last-pair-probs faster. ! Its probability estimates are a tiny
	bit different (more reproducible).
	[3e33f2821612]

	* scripts/last-pair-probs.py:
	Made last-pair-probs a bit faster.
	[ed4fbac1d8cf]

	* scripts/last-pair-probs.py:
	Minor refactoring.
	[6f4723d5a83e]

	* scripts/last-pair-probs.py:
	Made last-pair-probs a bit faster.
	[57912534f799]

	* scripts/last-pair-probs.py:
	Minor refactoring.
	[52b150cb1a88]

	* scripts/last-pair-probs.py:
	! Slightly changed how last-pair-probs estimates the standard
	deviation.
	[48a62711ce44]

	* doc/last-pair-probs.txt, scripts/last-pair-probs.py:
	! Changed how last-pair-probs obtains the genome size. This may
	slightly change its probability estimates.
	[f50079ca2227]

2012-05-27  Martin C. Frith  <Martin C. Frith>

	* scripts/last-pair-probs.py:
	Fixed error in last-pair-probs help message.
	[655c1f9449c6]

2012-05-20  Martin C. Frith  <Martin C. Frith>

	* src/AlignmentWrite.cc:
	Fixed a bug that was introduced in version 203 (wrong MAF sequence
	length).
	[0afc11fd9d18]

	* doc/lastal.txt, src/LastalArguments.cc, test/last-test.out:
	! Made lastal options -d and -e synonymous for gapless alignment
	(-j1).
	[977c23d24eb5]

	* doc/FAQ.txt, src/AlignmentWrite.cc, src/Alphabet.cc,
	src/Alphabet.hh:
	Made lastal yet faster at writing MAF output.
	[2b70fa3cd0c3]

2012-05-17  Martin C. Frith  <Martin C. Frith>

	* src/Alignment.hh, src/AlignmentWrite.cc, src/Alphabet.cc,
	src/Alphabet.hh:
	Made lastal even faster at writing MAF output.
	[82625cec7dbc]

	* src/AlignmentWrite.cc:
	Minor refactoring.
	[bcc17bd99c42]

	* src/AlignmentWrite.cc:
	Minor refactoring.
	[ddbc9b8efeba]

2012-05-16  Martin C. Frith  <Martin C. Frith>

	* src/AlignmentWrite.cc:
	Made lastal faster at writing MAF output.
	[78a9da37f5a3]

2012-05-14  Martin C. Frith  <Martin C. Frith>

	* src/SegmentPair.cc:
	Made lastal a teeny bit faster.
	[0a121eb763c5]

	* scripts/last-split-probs.py:
	Minor changes to last-split-probs.
	[90f3031116aa]

2012-05-11  Martin C. Frith  <Martin C. Frith>

	* doc/last-split-probs.txt, scripts/last-split-probs.py:
	Added split-alignment method!
	[294db1a62968]

2012-05-07  Martin C. Frith  <Martin C. Frith>

	* src/makefile:
	Improved the makefile.
	[2248af12c158]

2012-03-30  Martin C. Frith  <Martin C. Frith>

	* README.txt, makefile, src/makefile:
	Turned compile warnings off in the top makefile, on in the src
	makefile.
	[0f45f4585048]

	* src/gumbel_params/njn_approx.hpp:
	Fixed compile error with clang++.
	[4582086da692]

2012-03-13  Martin C. Frith  <Martin C. Frith>

	* README.txt, makefile, src/makefile, test/last-test.sh:
	Added automatic installation by "make install".
	[6f1d925a06c6]

2012-01-06  Martin C. Frith  <Martin C. Frith>

	* doc/lastdb.txt, src/Alignment.cc, src/Alignment.hh,
	src/LastdbArguments.cc, src/lastal.cc, src/makefile:
	Fully enabled fastq-versus-fastq alignment!
	[a8bdd8c9d9d4]

	* doc/bisulfite.txt:
	Clarified something in the bisulfite doc.
	[e3b276863a2d]

2011-12-20  Martin C. Frith  <Martin C. Frith>

	* doc/bisulfite.txt, examples/bisulfite_f.seed,
	examples/bisulfite_r.seed:
	Bisulfite doc: explained biased methylation estimates & how to avoid
	them. Changed the bisulfite seeds to ones that work a bit better in
	some tests.
	[4a4af87299d7]

2011-11-13  Martin C. Frith  <Martin C. Frith>

	* src/Alignment.cc, src/Alignment.hh, src/Centroid.cc,
	src/Centroid.hh, src/ScoreMatrix.hh, src/ScoreMatrixRow.hh,
	src/Xdrop3FrameAligner.cc, src/Xdrop3FrameAligner.hh,
	src/XdropAligner.cc, src/XdropAligner.hh, src/XdropAlignerPssm.cc,
	src/lastal.cc, src/makefile, test/last-test.out:
	Switched to new gapped-alignment code: faster and simpler.

	! The placement of frameshifts is different (probably better).

	! Near ends of sequences: column ambiguity estimates (and thus
	gamma-centroid and LAMA alignments) are slightly different.
	[0ef8ab8aa902]

	* src/Alignment.cc, src/Alignment.hh, src/Centroid.cc,
	src/Centroid.hh:
	Refactor: preparing to remove the old gapped-alignment code.
	[2b59e5d2cc40]

2011-11-12  Martin C. Frith  <Martin C. Frith>

	* src/Alignment.hh, src/Centroid.cc, src/Centroid.hh,
	src/GeneticCode.cc, src/ScoreMatrix.cc:
	Made the C++ more strictly correct and portable. (Thanks: Fabien
	Campagne)
	[15f74143b748]

2011-10-19  Martin C. Frith  <Martin C. Frith>

	* src/lastal.cc:
	Bugfix: lastal -j0 crashed with fastq input. (Thanks: Fabien
	Campagne)
	[beb8f40d2a0d]

2011-10-15  Martin C. Frith  <Martin C. Frith>

	* src/SubsetSuffixArraySort.cc:
	Made lastdb faster in some cases, e.g. bisulfite alignment.
	[6c7c721e1a3c]

2011-09-20  Martin C. Frith  <Martin C. Frith>

	* src/GappedXdropAligner3frame.cc:
	Just fixed a comment that was wrong.
	[99517a30d10f]

2011-08-17  Martin C. Frith  <Martin C. Frith>

	* src/GappedXdropAligner.cc, src/GappedXdropAligner3frame.cc:
	Added comments explaining the new gapped X-drop algorithms in more
	detail.
	[1c8bcac7122c]

2011-08-15  Martin C. Frith  <Martin C. Frith>

	* src/GappedXdropAligner.cc, src/GappedXdropAligner.hh,
	src/GappedXdropAligner2qual.cc, src/GappedXdropAligner3frame.cc,
	src/GappedXdropAligner3framePssm.cc, src/GappedXdropAlignerInl.hh,
	src/GappedXdropAlignerPssm.cc:
	Added new gapped x-drop alignment code (not used yet).
	[2e40cac8a24f]

2011-08-03  Martin C. Frith  <Martin C. Frith>

	* doc/bisulfite.txt, scripts/last-merge-batches.py:
	Added bisulfite doc, and a script that it refers to.
	[f7dee5ac617b]

2011-07-28  Martin C. Frith  <Martin C. Frith>

	* doc/lastal.txt, doc/lastex.txt, examples/HOXD70, examples/TiTv212,
	examples/bisulfite_f.mat, examples/bisulfite_f.seed,
	examples/bisulfite_r.mat, examples/bisulfite_r.seed,
	examples/hoxd70.mat, examples/titv212.mat, test/last-test.sh:
	Added bisulfite example files, and renamed score-matrix files.
	[45c7af0a029b]

	* test/last-test.out:
	Fixed error in test output, in the previous commit.
	[c6ed0024a2fd]

	* test/last-test.out, test/last-test.sh:
	Added a test of probabilistic alignment with quality scores.
	[b7803b71b74d]

	* doc/last-pair-probs.txt, scripts/last-pair-probs.py:
	Changed how last-pair-probs interprets read names to recognize
	paired reads.
	[13f60cb07842]

2011-07-15  Martin C. Frith  <Martin C. Frith>

	* README.txt:
	Just fixed a citation.
	[671d7d26ccef]

2011-06-07  Martin C. Frith  <Martin C. Frith>

	* src/gumbel_params/njn_localmaxstat.hpp,
	src/gumbel_params/sls_pvalues.cpp:
	Fixed lastex crashing on some systems. (Thanks: Edward Wijaya)
	[6bbd46d308f3]

2011-06-03  Martin C. Frith  <Martin C. Frith>

	* doc/last-tutorial.txt, doc/lastal.txt, doc/maf-convert.txt,
	examples/multiMito.maf, scripts/maf-convert.py, scripts/maf-join.py,
	scripts/maf-swap.py, src/Alignment.cc, src/Alignment.hh,
	src/AlignmentWrite.cc, src/Centroid.cc, src/Centroid.hh,
	src/LastalArguments.cc, test/last-test.out:
	! Changed column probabilities in lastal output, from numbers to
	ASCII codes. ! Changed some scripts to read the new format, but not
	the old. Added documentation for probabilistic alignment.
	[67a953e00e55]

2011-05-29  Martin C. Frith  <Martin C. Frith>

	* src/SegmentPairPot.cc:
	Fixed lastal slowness when self-comparing many short sequences.
	[d6192a3c88ef]

2011-05-25  Martin C. Frith  <Martin C. Frith>

	* src/Centroid.hh:
	Fixed a compile error with some compilers.
	[6bfb15a7f1d5]

	* src/Alignment.cc, src/Centroid.cc, src/Centroid.hh,
	src/LastalArguments.cc, src/lastal.cc:
	Enabled probabilistic alignment with sequence quality data, and LAMA
	(not documented yet).
	[cb423a218e96]

2011-05-19  Martin C. Frith  <Martin C. Frith>

	* src/SegmentPair.cc, src/SegmentPair.hh, src/SegmentPairPssm.cc,
	src/gaplessPssmXdrop.cc, src/gaplessPssmXdrop.hh,
	src/gaplessTwoQualityXdrop.cc, src/gaplessTwoQualityXdrop.hh,
	src/gaplessXdrop.cc, src/gaplessXdrop.hh, src/lastal.cc,
	src/makefile:
	Made lastal's gapless extensions a bit faster.
	[3734b1b92586]

	* src/MultiSequence.hh, src/lastal.cc, test/last-test.out:
	Write reference size in the lastal output header.
	[0d9ecd24c1f5]

2011-05-10  Martin C. Frith  <Martin C. Frith>

	* README.txt, doc/FAQ.txt, doc/lastex.txt, scripts/maf-convert.py,
	src/LastdbArguments.hh, src/SegmentPairPot.hh, src/XdropAligner.hh,
	src/fileMap.hh, test/last-test.sh:
	Added some clarifications to the docs. Made the C++ compile more
	portably. (Thanks: Andreas Tille) Fixed alignment spacing in maf-
	convert HTML output, for some evil browsers.
	[0e43facd304b]

2011-04-20  Martin C. Frith  <Martin C. Frith>

	* src/MultiSequence.cc, src/MultiSequence.hh, src/lastal.cc,
	src/makefile:
	Enable lastal to read quality data written by lastdb (not useful
	yet).
	[a2c237e87290]

	* src/LastdbArguments.cc, src/LastdbArguments.hh, src/lastdb.cc,
	src/makefile:
	Enabled lastdb to read fastq data (not yet useful).
	[253d2a669c72]

	* src/LastalArguments.cc, src/LastalArguments.hh,
	src/SequenceFormat.hh, src/lastal.cc, src/makefile:
	Refactor: extracted an enum.
	[f07685f9dd74]

2011-04-19  Martin C. Frith  <Martin C. Frith>

	* src/MultiSequence.hh, src/MultiSequenceQual.cc:
	Refactor: made the quality data mmap-able.
	[044a53b12c42]

	* src/Alignment.hh, src/AlignmentWrite.cc, src/VectorOrMmap.hh:
	Enable writing of qualities for both sequences in maf output.
	[2ba224d5ad0c]

	* src/OneQualityScoreMatrix.hh, src/TwoQualityScoreMatrix.cc,
	src/TwoQualityScoreMatrix.hh, src/VectorOrMmap.hh,
	src/qualityScoreUtil.hh:
	Minor code enhancements.
	[93e9a81040c8]

2011-04-15  Martin C. Frith  <Martin C. Frith>

	* doc/lastal.txt, src/MultiSequenceQual.cc,
	src/OneQualityScoreMatrix.cc, src/OneQualityScoreMatrix.hh,
	src/QualityPssmMaker.cc, src/QualityPssmMaker.hh,
	src/QualityScoreCalculator.cc, src/QualityScoreCalculator.hh,
	src/ScoreMatrix.cc, src/TwoQualityScoreMatrix.cc,
	src/TwoQualityScoreMatrix.hh, src/lastal.cc, src/makefile,
	src/qualityScoreUtil.hh:
	! Use more "gentle" substitution costs when masking lowercase
	letters.

	Made fastq probabilities and scores depend on the background letter
	frequencies of the score matrix.

	Made alignment scores with quality data ignore the lastal -t option.

	Made alignment scores for non-ACGT letters always ignore quality
	data.
	[18fc36efc723]

2011-04-14  Martin C. Frith  <Martin C. Frith>

	* test/last-test.out, test/last-test.sh, test/mouse_tss_prb.txt:
	Added a test for sequence quality data in prb format.
	[2027f4e14326]

2011-03-29  Martin C. Frith  <Martin C. Frith>

	* doc/last-pair-probs.txt, scripts/last-map-probs.py, scripts/last-
	pair-probs.py, src/makefile:
	Added --rna option to last-pair-probs.
	[3ac7c4da5743]

2011-03-28  Martin C. Frith  <Martin C. Frith>

	* doc/FAQ.txt, src/Xdrop3FrameAligner.cc:
	!! Bugfix: the DNA-vs-protein gapped extension was losing some good
	alignments.
	[37bdfb545cc9]

2011-03-22  Martin C. Frith  <Martin C. Frith>

	* doc/last-map-probs.txt, scripts/last-map-probs.py:
	Made last-map-probs read its input just once, to avoid huge temp
	files. Tried to clarify the last-map-probs document.
	[5068d4835985]

2011-02-14  Martin C. Frith  <Martin C. Frith>

	* doc/FAQ.txt, doc/last-map-probs.txt, doc/last-pair-probs.txt, doc
	/last-tutorial.txt, doc/tag-seeds.txt, scripts/last-pair-probs.py,
	scripts/maf-sort.sh, src/Alphabet.cc:
	Added last-pair-probs script and document. Allow "." in sequences
	(appears in some fastq files). Made maf-sort more efficient.
	[6c6ac7c8f6ed]

2011-02-08  Martin C. Frith  <Martin C. Frith>

	* doc/last-scripts.txt, doc/maf-cull.txt, scripts/maf-sort.sh:
	Bugfix: maf-sort mangled alignment data containing "#". Added maf-
	sort option to sort by sequences other than the top one.
	[edcab3015d61]

2011-01-31  Martin C. Frith  <Martin C. Frith>

	* doc/last-map-probs.txt, doc/last-tutorial.txt, doc/lastal.txt,
	scripts/maf-convert.py, src/lastal.cc:
	Made the documentation for last-map-probs actually usable. Bugfix:
	maf-convert was spuriously deleting seq quality codes in sam output.
	Bugfix: lastal with PSSM input could find inferior gapped
	alignments.
	[03d481e668b5]

2011-01-19  Martin C. Frith  <Martin C. Frith>

	* scripts/maf-convert.py:
	Bugfix: sam headers should be tab-delimited.
	[3bdbbd585326]

2011-01-08  Martin C. Frith  <Martin C. Frith>

	* doc/maf-convert.txt, scripts/maf-convert.py:
	Added sam header option to maf-convert.
	[effa83a4ab04]

2011-01-07  Martin C. Frith  <Martin C. Frith>

	* doc/last-map-probs.txt, doc/last-tutorial.txt, doc/maf-convert.txt:
	Removed discussion of repeats from docs.
	[3d8ccc865d9c]

2010-12-29  Martin C. Frith  <Martin C. Frith>

	* src/LastalArguments.cc, src/lastal.cc:
	Allow all types of lowercase masking when using sequence quality
	data.
	[e61008375f19]

2010-12-28  Martin C. Frith  <Martin C. Frith>

	* README.txt, doc/last-tutorial.txt, doc/lastal.txt:
	Improved the documents (thanks: Hamada-san, Terai-san.
	[fc13354d5296]

2010-12-09  Martin C. Frith  <Martin C. Frith>

	* README.txt, doc/FAQ.txt, doc/last-manual.txt, doc/last-tutorial.txt,
	doc/lastal.txt, doc/lastdb.txt, doc/tag-seeds.txt,
	src/LastalArguments.cc:
	Rewrote much of the documentation: separated tutorial from
	reference.
	[548a2c0737e3]

	* doc/maf-convert.txt, examples/multiMito.sh, scripts/maf-convert.py:
	Bugfix: made maf-convert not crash for blast output format!
	[2d744992211f]

2010-11-26  Martin C. Frith  <Martin C. Frith>

	* doc/last-map-probs.txt, scripts/maf-convert.py:
	Minor enhancements.
	[09d184ab20ae]

2010-11-25  Martin C. Frith  <Martin C. Frith>

	* doc/last-map-probs.txt, doc/last-scripts.txt, doc/maf-convert.txt,
	scripts/last-map-probs.py, scripts/maf-convert.py:
	! Made last-map-probs write *mismap* probabilities. Gave last-map-
	probs options to omit alignments with lo score or hi mismap-prob.
	Made last-map-probs work on MAF, and improved its UI a bit. Added
	SAM output format to maf-convert. Made maf-convert count psl matches
	correctly, and added -p (protein) option. Added documents for last-
	map-probs and maf-convert.
	[f19b6c1181db]

	* scripts/maf-swap.py:
	Made maf-swap keep q lines with s lines.
	[f2a92617f255]

2010-11-18  Martin C. Frith  <Martin C. Frith>

	* src/QualityScoreCalculator.cc:
	Added a partial check for wrong FASTQ format.
	[25b71c13313a]

2010-11-12  Martin C. Frith  <Martin C. Frith>

	* doc/maf-cull.txt, scripts/maf-cull.py:
	Added alignment-culling script.
	[2d7d24ffbaf0]

	* doc/last-scripts.txt, scripts/maf-sort.sh, scripts/maf-swap.py:
	Made maf-sort.sh consider the strand of the top sequence. Rewrote
	maf-convert.py: nicer spacing, nicer error messages, and doesn't try
	to flip strands for translated DNA.
	[bd0c70e36eed]

2010-11-08  Martin C. Frith  <Martin C. Frith>

	* test/illumina100.txt:
	Added a new test file (forgotten in the previous commit).
	[fb7b4acda59d]

	* doc/last-manual.txt, src/LastalArguments.cc, src/LastalArguments.hh,
	src/QualityScoreCalculator.cc, src/lastal.cc, test/last-test.out,
	test/last-test.sh:
	! Changed the interpretation of lastal -Q, to add FASTQ-Illumina
	input format.
	[980c3aa1552f]

	* src/LastalArguments.cc, src/LastalArguments.hh, src/lastal.cc,
	src/makefile:
	Refactor: use an enum instead of obscure int values.
	[711539bf55bc]

2010-11-02  Martin C. Frith  <Martin C. Frith>

	* doc/last-scripts.txt, scripts/maf-convert.py, scripts/maf2html.py:
	Added psl and blast-like outputs to maf-convert.py. Merged
	maf2html.py into maf-convert.py. Bugfix: the html coordinates were
	wrong for translated alignments.
	[977125273601]

2010-10-13  Martin C. Frith  <Martin C. Frith>

	* scripts/last-map-probs.py:
	Fixed last-map-probs.py crashing (math overflow) on large
	alignments.
	[fd7ebdab1b09]

2010-10-12  Martin C. Frith  <Martin C. Frith>

	* doc/FAQ.txt, doc/last-manual.txt, doc/tag-seeds.txt,
	src/LastdbArguments.cc:
	Made lastdb's default volume size (-s) unlimited, to simplify
	typical usage.
	[bd155781bf7a]

	* src/LastalArguments.cc, src/LastalArguments.hh, src/lastal.cc, test
	/last-test.out:
	Changed the default setting of lastal -u: made it depend on lastdb
	-c.
	[9e28051e245c]

	* doc/last-manual.txt, src/LastalArguments.cc, src/LastalArguments.hh,
	src/lastal.cc, test/last-test.out:
	Added lastal -z option: maximum score drop for final gapped
	alignments.
	[6d4d82b3b427]

	* doc/last-manual.txt, src/LastalArguments.cc, src/SegmentPairPot.cc,
	src/SegmentPairPot.hh, src/lastal.cc:
	! Changed lastal -u: new option to mask lowercase during gapped
	extensions but not "final" extensions (i.e. do gapped extensions
	twice).
	[4f0640e38978]

	* scripts/last-dotplot.py, scripts/last-map-probs.py:
	Added colour options to the dotplot script.
	[e908650d665a]

2010-08-20  Martin C. Frith  <Martin C. Frith>

	* src/SegmentPair.hh, src/SegmentPairPot.cc, src/SegmentPairPot.hh,
	src/lastal.cc:
	Reorganized code for gapless & gapped extensions. Results should be
	identical, provided that max gapped dropoff >= max gapless dropoff.
	[10b733b90b9b]

	* src/SegmentPairPot.cc, src/SegmentPairPot.hh, src/lastal.cc:
	Minor refactoring.
	[efe9ee7fecf7]

2010-08-19  Martin C. Frith  <Martin C. Frith>

	* src/gumbel_params/mcf_local_alignment_evaluer.cpp, src/lastex.cc:
	Made lastex check for bad input more carefully.
	[d934e2242ad2]

2010-08-04  Martin C. Frith  <Martin C. Frith>

	* src/CyclicSubsetSeed.cc:
	Bugfix: made lastdb allow non-alphabetic symbols in user-defined
	alphabets.
	[f2d461a671f8]

2010-08-03  Martin C. Frith  <Martin C. Frith>

	* src/CA_code/lambda_calculator.c, src/QualityScoreCalculator.cc,
	src/lastdb.cc:
	Bugfix: stopped lastal from freezing with some score matrices, e.g.
	PAM70. Made "lastdb -x" less likely to run out of memory. (Thanks:
	Junko Tsuji)
	[8649e85be4c2]

2010-06-28  Martin C. Frith  <Martin C. Frith>

	* scripts/last-dotplot.py, src/MultiSequence.cc,
	src/MultiSequenceQual.cc:
	Bugfix: made last-dotplot.pl check for no alignments, instead of
	crashing. Made lastdb and lastal check for '>' in FASTA and '@' in
	FASTQ.
	[3f6d0bf8c8dd]

2010-06-24  Martin C. Frith  <Martin C. Frith>

	* src/gumbel_params/mcf_local_alignment_evaluer.cpp:
	Made lastex results more reproducible, by removing time limits.
	[becf89661310]

2010-06-20  Martin C. Frith  <Martin C. Frith>

	* doc/last-manual.txt, src/MultiSequence.hh, src/MultiSequenceQual.cc:
	Read PSSM names; ensure lastal doesn't try to use non-existent
	PSSMs.
	[731614e5b9c5]

2010-06-18  Martin C. Frith  <Martin C. Frith>

	* src/LastalArguments.cc:
	Clarified the default values of some lastal options.
	[98e8f237f77a]

	* src/lastal.cc:
	Bugfix: the PSSM reverse-complementation routine was wrong.
	[539c1c670daa]

	* doc/last-manual.txt, src/LastalArguments.cc, src/LastalArguments.hh,
	src/MultiSequence.hh, src/MultiSequenceQual.cc,
	src/ScoreMatrixRow.hh, src/lastal.cc, src/makefile:
	Allow PSSMs as queries for lastal!
	[620742f1b380]

2010-06-17  Martin C. Frith  <Martin C. Frith>

	* src/lastex.cc:
	Made lastex sensibly handle a both-strand translated alignments
	file.
	[449b5ece6113]

	* src/CA_code/lambda_calculator.c, src/QualityScoreCalculator.hh,
	src/ScoreMatrix.cc, src/XdropAlignerPssm.cc,
	src/gumbel_params/sls_alp_data.cpp:
	Bugfix: made lastex work with weird letter frequencies (asymmetric
	with zeros). Improved some error messages & other minor code
	improvements.
	[7cb04489fe4d]

2010-06-02  Martin C. Frith  <Martin C. Frith>

	* scripts/maf-convert.py:
	Made maf-convert.py write expect values in tab output, if present in
	the input.
	[fd95006a5bf7]

2010-05-17  Martin C. Frith  <Martin C. Frith>

	* src/lastdb.cc, src/lastex.cc:
	Fixed compilation error & warning that occurred on some systems.
	[a4096022c048]

2010-05-14  Martin C. Frith  <Martin C. Frith>

	* doc/lastex.txt, src/AlignmentPot.cc, src/Alphabet.cc,
	src/Centroid.cc, src/CyclicSubsetSeed.cc, src/DiagonalTable.hh,
	src/GeneticCode.cc, src/LastalArguments.cc, src/Mmap.hh,
	src/ScoreMatrix.cc, src/SubsetSuffixArraySort.cc, src/io.cc:
	Tried to make the C++ more strictly correct and portable.
	[b69cf6df7e1f]

2010-05-12  Martin C. Frith  <Martin C. Frith>

	* src/makefile:
	Try to put the correct version number in lastex's output.
	[5661473b83f7]

	* makefile, src/lastex.cc:
	Write the version number in lastex's output. Exclude executable
	files from the distribution.
	[f88aec669c0e]

	* doc/evalue-tables.txt, doc/last-manual.txt, doc/last-scripts.txt,
	doc/lastex.txt, examples/HOXD70, examples/TiTv212, makefile,
	src/LastexArguments.cc, src/LastexArguments.hh,
	src/gumbel_params/common/ncbi_export.h,
	src/gumbel_params/corelib/ncbi_limits.h,
	src/gumbel_params/corelib/ncbidbg.hpp,
	src/gumbel_params/corelib/ncbistd.hpp,
	src/gumbel_params/corelib/ncbistl.hpp,
	src/gumbel_params/corelib/ncbistre.hpp,
	src/gumbel_params/corelib/ncbitype.h,
	src/gumbel_params/mcf_local_alignment_evaluer.cpp,
	src/gumbel_params/mcf_local_alignment_evaluer.hpp,
	src/gumbel_params/ncbi_pch.hpp, src/gumbel_params/njn_approx.hpp,
	src/gumbel_params/njn_doubletype.hpp,
	src/gumbel_params/njn_dynprogprob.cpp,
	src/gumbel_params/njn_dynprogprob.hpp,
	src/gumbel_params/njn_dynprogproblim.cpp,
	src/gumbel_params/njn_dynprogproblim.hpp,
	src/gumbel_params/njn_dynprogprobproto.cpp,
	src/gumbel_params/njn_dynprogprobproto.hpp,
	src/gumbel_params/njn_function.hpp,
	src/gumbel_params/njn_integer.hpp, src/gumbel_params/njn_ioutil.cpp,
	src/gumbel_params/njn_ioutil.hpp,
	src/gumbel_params/njn_localmaxstat.cpp,
	src/gumbel_params/njn_localmaxstat.hpp,
	src/gumbel_params/njn_localmaxstatmatrix.cpp,
	src/gumbel_params/njn_localmaxstatmatrix.hpp,
	src/gumbel_params/njn_localmaxstatutil.cpp,
	src/gumbel_params/njn_localmaxstatutil.hpp,
	src/gumbel_params/njn_matrix.cpp, src/gumbel_params/njn_matrix.hpp,
	src/gumbel_params/njn_memutil.hpp, src/gumbel_params/njn_root.hpp,
	src/gumbel_params/njn_vector.hpp, src/gumbel_params/random_gen.cpp,
	src/gumbel_params/sls_alp.cpp, src/gumbel_params/sls_alp.hpp,
	src/gumbel_params/sls_alp_data.cpp,
	src/gumbel_params/sls_alp_data.hpp,
	src/gumbel_params/sls_alp_regression.cpp,
	src/gumbel_params/sls_alp_regression.hpp,
	src/gumbel_params/sls_alp_sim.cpp,
	src/gumbel_params/sls_alp_sim.hpp,
	src/gumbel_params/sls_normal_distr_array.hpp,
	src/gumbel_params/sls_pvalues.cpp,
	src/gumbel_params/sls_pvalues.hpp,
	src/gumbel_params/util/random_gen.hpp, src/lastex.cc, src/makefile:
	Added lastex: expected numbers of alignments for random sequences!
	[0356ab56fc53]

	* src/LastalArguments.cc, src/LastalArguments.hh, test/asymmetric.mat:
	Changed the prefix for options in the matrix file, from "#lastal" to
	just "#last". ("#lastal" still works.)
	[3a8017f99bce]

	* src/lastdb.cc:
	Added lastdb warning if the input doesn't look like DNA.
	[489e81296b19]

2010-05-10  Martin C. Frith  <Martin C. Frith>

	* src/LastdbArguments.cc, src/LastdbArguments.hh, src/lastdb.cc:
	Gave lastdb an option to just count sequences & letters.
	[86faa9559bca]

	* src/Alphabet.cc, src/Alphabet.hh, src/lastdb.cc:
	Made lastdb count sequences & letters (not used yet).
	[5d322b56849a]

	* src/MultiSequence.cc:
	Made FASTA-reading faster.
	[2d05b4ae9488]

2010-05-08  Martin C. Frith  <Martin C. Frith>

	* doc/last-manual.txt, src/LambdaCalculator.hh,
	src/LastdbArguments.cc, src/lastdb.cc:
	Made yass.seed the default for DNA only.
	[223bac5a97a9]

2010-04-08  Martin C. Frith  <Martin C. Frith>

	* src/CA_code/lambda_calculator.c, src/CA_code/lambda_calculator.h,
	src/LambdaCalculator.cc, src/LambdaCalculator.hh, src/lastal.cc,
	test/last-test.out:
	Rewrote some code for getting probabilities from a scoring matrix.
	[d984c04b8599]

	* test/asymmetric.mat, test/last-test.out, test/last-test.sh:
	Added a test with an asymmetric scoring matrix.
	[a79e00ba5f46]

	* doc/last-manual.txt, src/Alignment.cc, src/Alignment.hh,
	src/AlignmentWrite.cc, test/last-test.out:
	Made centroid alignment report the score of the ordinary gapped
	alignment.
	[cee3aa1623dc]

	* src/AlignmentWrite.cc, src/lastal.cc, src/lastdb.cc:
	Minor refactoring.
	[ea70b9170817]

	* src/GeneralizedAffineGapCosts.hh, src/Xdrop3FrameAligner.cc,
	src/XdropAligner.cc, src/io.hh:
	Made file I/O error messages a bit more specific; minor refactoring.
	[cde91a34dd89]

2010-04-02  Martin C. Frith  <Martin C. Frith>

	* doc/FAQ.txt, doc/evalue-tables.txt, doc/last-manual.txt, doc/tag-
	seeds.txt, examples/multiMito.sh, src/Alignment.hh,
	src/CyclicSubsetSeed.cc, src/CyclicSubsetSeed.hh,
	src/LastdbArguments.cc, src/SegmentPairPot.hh,
	src/SubsetSuffixArraySort.cc, src/lastal.cc, src/lastdb.cc, test
	/last-test.sh:
	Made yass.seed the default seed pattern. Greatly improved the
	documents & LAST recipes: please re-read them!
	[24f943b3495a]

2010-03-23  Martin C. Frith  <Martin C. Frith>

	* scripts/maf-convert.py, src/LastalArguments.cc,
	src/LastdbArguments.cc, src/SubsetSuffixArray.cc,
	src/SubsetSuffixArray.hh, src/lastal.cc, src/lastdb.cc:
	Made maf-convert.py work with older versions of python. Avoided some
	warnings with some compilers.
	[21e8d6b7a674]

	* doc/last-scripts.txt, scripts/maf-convert.py, scripts/maf2tab.py:
	Bugfix: maf2tab didn't work on translated alignments. Replaced it
	with maf-convert.py (can also write AXT format).
	[56fd23dee4be]

2010-03-18  Martin C. Frith  <Martin C. Frith>

	* doc/last-manual.txt, src/Alignment.hh, src/AlignmentWrite.cc,
	src/MultiSequence.cc, src/MultiSequence.hh,
	src/MultiSequenceQual.cc, src/lastal.cc, src/lastdb.cc:
	Bugfix: fixed errors related to volumes and batches >~4 gigabytes.
	[d91b6a9d0bfb]

2010-03-06  Martin C. Frith  <Martin C. Frith>

	* scripts/maf2tab.py, src/lastal.cc, test/last-test.out:
	Made lastal write a comment line between query batches: might help
	parsers. Made maf2tab.py preserve comment lines (but it might move
	them).
	[232af295bff6]

2010-02-27  Martin C. Frith  <Martin C. Frith>

	* doc/last-manual.txt, doc/tag-seeds.txt, src/LastalArguments.cc,
	src/LastalArguments.hh, src/LastdbArguments.cc, src/lastal.cc, test
	/last-test.out:
	Added lastal -n option to limit gapless alignments.
	[69172cf2778d]

2010-02-16  Martin C. Frith  <Martin C. Frith>

	* examples/TiTv212, src/LastalArguments.cc, src/LastdbArguments.cc:
	Made lastdb and lastal require at least one sequence file.
	[24ef4fb0d864]

2010-02-02  Martin C. Frith  <Martin C. Frith>

	* doc/last-manual.txt, src/Mmap.hh, src/MultiSequence.cc,
	src/MultiSequence.hh, src/MultiSequenceQual.cc,
	src/SubsetSuffixArray.cc, src/SubsetSuffixArray.hh,
	src/SubsetSuffixArraySort.cc, src/VectorOrMmap.hh, src/fileMap.cc,
	src/fileMap.hh, src/makefile:
	Enabled memory sharing by parallel lastal runs.
	[e2171f4d2fde]

2010-02-01  Martin C. Frith  <Martin C. Frith>

	* doc/last-scripts.txt, scripts/last-dotplot.py:
	Enable dotplots to have zero margins.
	[f6c21d78378a]

2010-01-31  Martin C. Frith  <Martin C. Frith>

	* doc/FAQ.txt, scripts/last-map-probs.py, scripts/last-remove-
	dominated.py, scripts/maf-join.py, scripts/maf-sort.sh, scripts/maf-
	swap.py, scripts/maf2html.py, scripts/maf2tab.py:
	Bugfix: made maf-sort.sh (and thus last-reduce-alignments.sh) work
	on Mac OS X, by not using "uniq".

	Stopped spurious error messages from python scripts.

	Slight FAQ re-wording.
	[9b9b3d422dcd]

2010-01-18  Martin C. Frith  <Martin C. Frith>

	* src/Alphabet.cc, src/Alphabet.hh, src/LastalArguments.cc:
	Fixed build error & warning that occurred on some platforms.
	[48eda6d3dc73]

	* doc/FAQ.txt, doc/last-manual.txt:
	Added citations & FAQs to the docs.
	[db3f15bf5c2e]

	* src/Alignment.hh, src/AlignmentWrite.cc, src/Alphabet.cc,
	src/Alphabet.hh, src/GeneticCode.cc, src/GeneticCode.hh,
	src/MultiSequence.cc, src/MultiSequence.hh, src/io.hh,
	src/lastal.cc, src/lastdb.cc:
	Refactor: finished encapsulating the sequence data.
	[988c97f73036]

2010-01-15  Martin C. Frith  <Martin C. Frith>

	* src/AlignmentWrite.cc, src/MultiSequence.hh, src/lastal.cc,
	src/lastdb.cc:
	Refactor: further reduced direct access to the seqeunce data...
	[e9fb994c7f43]

2010-01-14  Martin C. Frith  <Martin C. Frith>

	* src/Alignment.hh, src/AlignmentWrite.cc, src/Alphabet.cc,
	src/Alphabet.hh, src/MultiSequence.hh, src/lastal.cc:
	Refactor: reduce direct access to the seqeunce data (aim to
	encapsulate it).
	[97bf019f979f]

	* src/Alphabet.cc, src/Alphabet.hh:
	Refactor: simplified some code.
	[2a4e310a75d8]

2009-10-30  Martin C. Frith  <Martin C. Frith>

	* doc/FAQ.txt, doc/evalue-tables.txt, doc/last-manual.txt,
	src/Alignment.cc, src/AlignmentWrite.cc, src/Xdrop3FrameAligner.hh,
	src/lastal.cc:
	Bugfix: made lastal not crash when there are no identical matches to
	initiate gapped extensions (can happen with subset seeds).

	Improved & updated the documents.

	Made lastal frameshifting gapped extension a bit faster.
	[a6a6350e9130]

2009-10-29  Martin C. Frith  <Martin C. Frith>

	* src/XdropAligner.hh:
	Made lastal gapped extension a fair bit faster. (I don't understand
	why.)
	[29e993bcdf94]

	* src/Xdrop3FrameAligner.cc, src/XdropAligner.cc, src/XdropAligner.hh,
	src/XdropAlignerPssm.cc, src/lastal.cc:
	Made lastal gapped extension a bit faster. Made lastal -v write the
	count of initial matches.
	[f17b15f16c84]

2009-10-26  Martin C. Frith  <Martin C. Frith>

	* doc/last-manual.txt:
	Explain lowercase & repeats a bit in the manual.
	[197c09afb831]

	* src/SubsetSuffixArray.cc:
	Made lastal match-finding slightly faster.
	[1939a7f661cb]

2009-10-23  Martin C. Frith  <Martin C. Frith>

	* doc/last-manual.txt, examples/multiMito.sh, examples/myalns.maf,
	src/Alphabet.cc, src/Alphabet.hh, src/LastalArguments.cc,
	src/LastdbArguments.cc, src/lastal.cc, src/lastdb.cc, test/last-
	test.out, test/last-test.sh:
	! Lastdb and lastal no longer convert sequences to uppercase on
	reading. ! Lastdb -c now means: forbid lowercase in initial matches
	(in both sequences). ! Lastal -u numbers have changed (lowercase
	masking for extensions only). Simplified the documentation by de-
	emphasizing lastal -u.
	[993c8ffa844f]

2009-10-22  Martin C. Frith  <Martin C. Frith>

	* examples/yass.seed, src/lastal.cc, src/lastdb.cc, test/last-
	test.out, test/last-test.sh:
	Added a test of subset seeds; a few cosmetic changes.
	[a9dee751cc84]

	* doc/last-manual.txt, doc/tag-seeds.txt, src/Alphabet.cc,
	src/Alphabet.hh, src/CyclicSubsetSeed.cc, src/CyclicSubsetSeed.hh,
	src/LastalArguments.cc, src/LastdbArguments.cc,
	src/LastdbArguments.hh, src/PeriodicSpacedSeed.cc,
	src/PeriodicSpacedSeed.hh, src/SubsetSuffixArray.cc,
	src/SubsetSuffixArray.hh, src/SubsetSuffixArraySort.cc,
	src/SuffixArray.cc, src/SuffixArray.hh, src/SuffixArraySort.cc,
	src/lastal.cc, src/lastdb.cc, src/makefile:
	Implemented subset seeds! This makes lastdb and lastal a bit slower
	:-( ! The meaning of lastal -l has changed: it includes skipped
	positions now. ! The meaning of match-count output (lastal -j0) has
	changed in the same way. ! Skipped positions no longer tolerate
	lowercase or non-alphabet letters.
	[d8f213e7fcfa]

2009-10-21  Martin C. Frith  <Martin C. Frith>

	* src/SuffixArray.cc, src/SuffixArray.hh, src/lastal.cc:
	Just re-organized some calculations. Lastal will now refuse to read
	older lastdb databases if the bucket depth = 0.
	[b75124274b95]

2009-10-16  Martin C. Frith  <Martin C. Frith>

	* src/SuffixArray.hh, src/SuffixArraySort.cc:
	Trivially re-organised the suffix sorting code.
	[5df0e44baf76]

	* src/SuffixArray.cc, src/SuffixArray.hh, src/SuffixArraySort.cc,
	src/lastal.cc, src/lastdb.cc:
	Refactored the suffix array code yet more (removed the
	constructor)...
	[f66e82b62f6f]

	* src/PeriodicSpacedSeed.cc, src/PeriodicSpacedSeed.hh,
	src/SuffixArray.cc, src/SuffixArray.hh, src/SuffixArraySort.cc,
	src/lastal.cc, src/lastdb.cc:
	Refactored the suffix array code some more (removed reference
	members)...
	[b26861ffe380]

	* src/SuffixArray.hh, src/SuffixArraySort.cc:
	Refactored suffix sorting a bit.
	[2480447181f8]

2009-10-13  Martin C. Frith  <Martin C. Frith>

	* test/SRR001981-1k.fastq:
	Added missing FASTQ test data!
	[0bfadb999cb3]

	* src/Alignment.cc, src/Alphabet.cc, src/Alphabet.hh,
	src/SuffixArray.cc:
	Minor refactoring.
	[ecbe255af190]

	* src/SuffixArray.cc, src/SuffixArray.hh, src/SuffixArraySort.cc,
	src/lastdb.cc, src/makefile:
	Code reorganization.
	[91b883ed7dd7]

	* src/LastdbArguments.cc, src/LastdbArguments.hh, src/SuffixArray.cc,
	src/SuffixArray.hh, src/lastal.cc, src/lastdb.cc:
	Minor code cleaning.
	[db41c7b6f398]

2009-10-05  Martin C. Frith  <Martin C. Frith>

	* test/last-test.out, test/last-test.sh:
	Added a test with FASTQ sequence quality data.
	[45b643a37d64]

2009-10-04  Martin C. Frith  <Martin C. Frith>

	* src/LastalArguments.cc, src/LastalArguments.hh, src/lastal.cc, test
	/last-test.out, test/last-test.sh:
	Changed the default "maximum score dropoff for gapless extensions"
	(lastal -y): made it adapt better to the scoring matrix.
	[b3092a865c66]

	* doc/last-manual.txt, src/Alignment.cc, src/Alignment.hh,
	src/GeneticCode.hh, src/LastalArguments.cc, src/ScoreMatrix.hh,
	src/Xdrop3FrameAligner.cc, src/Xdrop3FrameAligner.hh,
	src/XdropAligner.cc, src/XdropAligner.hh, src/lastal.cc,
	src/makefile, test/last-test.out:
	Added frameshifting alignment!
	[0c5add9fff75]

2009-10-02  Martin C. Frith  <Martin C. Frith>

	* doc/last-manual.txt, scripts/last-dotplot.py, scripts/last-map-
	probs.py, scripts/last-reduce-alignments.sh, scripts/last-remove-
	dominated.py, scripts/maf-join.py, scripts/maf-sort.sh, scripts/maf-
	swap.py, scripts/maf2html.py, scripts/maf2tab.py,
	src/LastalArguments.cc, src/LastdbArguments.cc,
	src/LastdbArguments.hh, src/lastal.cc, src/lastdb.cc, test/last-
	test.out, test/last-test.sh:
	Improved Debian/GNU conformance of progam help messages. (Thanks:
	Andreas Tille)

	Bugfix: made last-reduce-alignments.sh better able to find the
	scripts that it calls.
	[d68ccbc06d73]

2009-09-30  Martin C. Frith  <Martin C. Frith>

	* doc/last-manual.txt, src/Alignment.cc, src/Alignment.hh,
	src/AlignmentWrite.cc, src/GeneralizedAffineGapCosts.cc,
	src/GeneticCode.cc, src/GeneticCode.hh, src/LastalArguments.hh,
	src/lastal.cc:
	Generalized some of the code in preparation for frameshifts.
	[926d2c979e2d]

2009-09-28  Martin C. Frith  <Martin C. Frith>

	* examples/vertebrateMito.gc, src/Alignment.hh, src/AlignmentWrite.cc,
	src/GeneticCode.cc, src/GeneticCode.hh, src/LastalArguments.cc,
	src/LastalArguments.hh, src/lastal.cc, src/makefile, test/Q2LCP8.fa,
	test/last-test.out, test/last-test.sh:
	Added translated alignment (but without frameshifts for now)!
	[82232c885289]

	* doc/last-manual.txt, doc/tag-seeds.txt, src/Alignment.hh,
	src/AlignmentWrite.cc, src/CA_code/lambda_calculator.c,
	src/LastalArguments.cc, src/SuffixArray.cc, src/lastal.cc, test
	/last-test.sh:
	!! Changed the lastal option letter for query input format from -F
	to -Q (so that -F can be used for frameshift cost).

	Bugfix: fixed crash when bucket depth = 0.

	Removed spurious message "no sensible solution in the plausible x
	range..."

	Minor code cleaning.
	[4ab7d1100a4b]

2009-09-24  Martin C. Frith  <Martin C. Frith>

	* src/SuffixArray.cc, src/SuffixArray.hh, src/lastal.cc,
	src/lastdb.cc:
	Changed the bucket data structure. Advantages:
	  * Uses only 80% as much memory, for a given bucket depth
	  * Simpler code
	  * Slightly faster construction (lastdb) Disadvantages:
	  * Slightly slower scanning (lastal), for a given bucket depth
	  * Changed database format !! Lastal now refuses to read older lastdb
	databases.
	[b6eac8b7ef80]

2009-09-15  Martin C. Frith  <Martin C. Frith>

	* doc/tag-seeds.txt, src/lastal.cc, test/last-test.out, test/last-
	test.sh:
	Bugfix: lastal match counts (-j 0) were not reset between query
	batches, so they were wrong for all but the first batch.

	Added a test for match counting.

	Improved the tag mapping documentation.
	[2cffd9814c4f]

2009-08-31  Martin C. Frith  <Martin C. Frith>

	* doc/last-scripts.txt, scripts/last-map-probs.py, src/lastal.cc, test
	/last-test.out:
	Added a script to calculate mapping probabilities (& minimal
	documentation). Made lastal always try to calculate lambda (hence
	default temperature).
	[e3aa13898c8a]

2009-08-22  Martin C. Frith  <Martin C. Frith>

	* src/SuffixArray.cc, src/SuffixArray.hh:
	Made lastdb faster for DNA, with a specialized 4-letter radix sort.
	[00533dfd758e]

	* doc/last-manual.txt, doc/tag-seeds.txt,
	src/QualityScoreCalculator.cc, src/QualityScoreCalculator.hh,
	src/SegmentPair.cc, src/lastal.cc, src/lastdb.cc:
	Fixed underflow error with phred score=0 and huge mismatch cost.
	Friendlier out-of-memory message. Improved the documentation a bit.
	[c4f692277a02]

2009-06-14  Martin C. Frith  <Martin C. Frith>

	* doc/last-manual.txt, doc/tag-seeds.txt, src/Alignment.cc,
	src/Alignment.hh, src/AlignmentWrite.cc, src/LastalArguments.cc,
	src/LastalArguments.hh, src/MultiSequence.hh,
	src/MultiSequenceQual.cc, src/QualityScoreCalculator.cc,
	src/QualityScoreCalculator.hh, src/SegmentPair.cc,
	src/SegmentPair.hh, src/SegmentPairPssm.cc, src/XdropAligner.cc,
	src/XdropAligner.hh, src/XdropAlignerPssm.cc, src/lastal.cc,
	src/makefile:
	Made lastal able to use sequence quality scores!
	[11287126adb6]

	* doc/tag-seeds.txt, scripts/maf-swap.py, src/Alphabet.cc,
	src/SegmentPairPot.hh, src/lastal.cc, src/makefile:
	Made gapped alignments more reproducible, by breaking ties when
	sorting gapless alignments. Now, the query batch size should really
	have no effect on the results.

	Rewrote the tag mapping document.

	Minor code improvements.
	[2cf11c3ac7d0]

2009-06-08  Martin C. Frith  <Martin C. Frith>

	* src/LastalArguments.cc, src/LastalArguments.hh, src/lastal.cc:
	Made lastal match-counting (-j 0) much faster, for short queries
	with a large minimum-depth option (-l).

	Refactor: neatened the setting of default option values for lastal.
	[561788605741]

2009-06-07  Martin C. Frith  <Martin C. Frith>

	* src/Alignment.cc, src/AlignmentWrite.cc, src/SegmentPair.cc,
	src/SegmentPair.hh, src/XdropAligner.cc, src/XdropAligner.hh,
	src/lastal.cc, src/makefile:
	Minor code re-organization.
	[635e94b537b2]

2009-05-30  Martin C. Frith  <Martin C. Frith>

	* src/MultiSequence.cc, src/MultiSequence.hh, src/SuffixArray.cc,
	src/lastal.cc, src/lastdb.cc, test/last-test.maf, test/last-
	test.out, test/last-test.sh:
	Bugfix: the lastdb volume size option (-s) wasn't always respected.
	Made lastal not needlessly re-read a single-volume lastdb database.
	Added a test (of database volumes & query batches). Some minor
	refactoring.
	[3e822d0420a6]

2009-05-27  Martin C. Frith  <Martin C. Frith>

	* doc/FAQ.txt, src/GeneralizedAffineGapCosts.hh, src/lastal.cc:
	Added a FAQ item. Refactor: reduced parameter-passing in lastal.cc.
	[49fb8c5ea7dd]

2009-05-08  Martin C. Frith  <Martin C. Frith>

	* doc/last-manual.txt, doc/last-scripts.txt, scripts/maf2html.py:
	Added maf2html.py: converts MAF-format alignments to coloured HTML
	format. Disguised the email address in last-manual.txt.
	[bf790a859c2a]

2009-05-02  Martin C. Frith  <Martin C. Frith>

	* scripts/last-dotplot.py, src/XdropAligner.cc, src/makefile:
	Made lastal gapped extension faster, by removing an assert
	(surprising). Bugfix: made last-dotplot.py not crash on small
	sequences.
	[726cb608cd2b]

2009-04-08  Martin C. Frith  <Martin C. Frith>

	* examples/myalns.maf, src/SegmentPair.cc:
	Minor code cleaning: variable name, comments.
	[b5d20c0600b5]

2009-04-02  Martin C. Frith  <Martin C. Frith>

	* doc/last-manual.txt, examples/myalns.maf:
	Updated examples/myalns.maf to reflect the new default score
	parameters. Minor changes to last-manual.txt.
	[9b28ee63a537]

2009-04-01  Martin C. Frith  <Martin C. Frith>

	* scripts/maf-sort.sh:
	Removed unnecessary robustness from maf-sort.sh, to avoid bugs in
	unix sort(!)
	[c935c2c76860]

	* doc/evalue-tables.txt, doc/last-manual.txt, doc/last-scripts.txt,
	doc/tag-seeds.txt, examples/HOXD70, examples/TiTv212,
	examples/chickenMito.fa, examples/mouseMito.fa,
	examples/multiMito.maf, examples/multiMito.sh, scripts/maf-join.py,
	scripts/maf-sort.sh, scripts/maf-swap.py, src/LastalArguments.cc:
	Added maf-join.py: joins pairwise alignments into multiple
	alignments! Added example files to illustrate usage of maf-join.py.
	Changed lastal default gap existence cost for DNA to 7. Changed
	lastal default gapped score threshold for DNA to 40. Added TiTv212
	scoring matrix to examples. maf-swap.py: Added -n option to move any
	sequence to the top. Updated the documents.
	[f5eadd663148]

2009-03-31  Martin C. Frith  <Martin C. Frith>

	* scripts/last-remove-dominated.py:
	Made last-remove-dominated.py faster.
	[b0006c034de9]

2009-03-30  Martin C. Frith  <Martin C. Frith>

	* doc/last-manual.txt, doc/tag-seeds.txt, scripts/maf-sort.sh,
	src/Alignment.cc, test/last-test.maf, test/last-test.sh:
	Added gaps to MAF probability lines: easier to parse. Made maf-
	sort.sh more robust. Improved the documents a bit.
	[e6f6ff270445]

2009-03-18  Martin C. Frith  <Martin C. Frith>

	* doc/last-manual.txt, src/LastalArguments.cc, src/LastdbArguments.cc,
	src/stringify.hh:
	Allow suffixes K(ibibyte), M(ebibyte), and G(ibibyte) for sizes.
	[1b144155c74c]

2009-03-06  Martin C. Frith  <Martin C. Frith>

	* src/Alignment.cc, src/Centroid.cc, src/Centroid.hh:
	Simplified the probability & centroid code. (Thanks: Hamada-san)
	[1121b0c98227]

2009-03-03  Martin C. Frith  <Martin C. Frith>

	* src/GeneralizedAffineGapCosts.cc, src/LastalArguments.cc, test/last-
	test.maf:
	Bugfix: overflow error made lastal discard some gapped alignments.
	[39b97ca18568]

2009-02-28  Martin C. Frith  <Martin C. Frith>

	* doc/last-manual.txt, examples/HOXD70, src/LastalArguments.cc,
	src/LastalArguments.hh, src/ScoreMatrix.cc, src/ScoreMatrix.hh,
	src/io.cc, src/io.hh, src/lastal.cc, test/last-test.sh:
	Allow lastal options to be set in the score-matrix file.
	[9d3956d3d902]

	* src/LastalArguments.cc, src/LastalArguments.hh,
	src/LastdbArguments.cc, src/LastdbArguments.hh, src/lastal.cc,
	src/lastdb.cc:
	Minor refactoring.
	[d0a950027ac7]

2009-01-30  Martin C. Frith  <Martin C. Frith>

	* src/Alphabet.cc:
	Bugfix: for protein alignments, tyrosine was forbidden in initial
	matches. !! Old lastdb protein databases won't work properly: you
	need to re-run lastdb.
	[de27a8780950]

2008-12-30  Martin C. Frith  <Martin C. Frith>

	* src/lastal.cc, src/lastdb.cc:
	Refactor: removed some namespace tedium from the code.
	[4f503fee369c]

2008-12-24  Martin C. Frith  <Martin C. Frith>

	* doc/evalue-tables.txt, doc/last-manual.txt, doc/tag-seeds.txt:
	Updated the documentation, including a table of optimal spaced
	seeds.
	[daaf5739510a]

2008-12-22  Martin C. Frith  <Martin C. Frith>

	* src/SuffixArray.cc:
	Made lastdb bucket-making code slightly simpler & faster.
	[57c165efb568]

	* src/LastalArguments.cc, src/SuffixArray.cc, src/io.hh:
	Enabled reading & writing of huge files (at least on one system with
	Linux-2.6.13/x86_64/gcc-4.0.2).

	Made lastdb radix sort a bit faster, with the oracle array trick.

	Allowed the mismatch score to be zero, due to a request.
	[3ca5ea230751]

2008-12-09  Martin C. Frith  <Martin C. Frith>

	* src/Alignment.cc, src/Alignment.hh, src/ScoreMatrix.hh,
	src/XdropAligner.cc, src/XdropAligner.hh, src/lastal.cc:
	Made gapped extension faster for short sequences (e.g. tag mapping).
	[60d29e3957c5]

2008-12-08  Martin C. Frith  <Martin C. Frith>

	* src/lastal.cc:
	Bugfix: the sequence names weren't printed correctly for match-
	counting output (-j 0).
	[12d9030cf05e]

2008-12-05  Martin C. Frith  <Martin C. Frith>

	* src/Alignment.cc, src/ScoreMatrix.cc, src/makefile:
	Fixed compiler warnings with gcc 4.3
	[18843b10d9e8]

2008-11-06  Martin C. Frith  <Martin C. Frith>

	* makefile:
	Added "." after "svnversion" to support older versions of svn.
	(Thanks: Nicolas Sierro)
	[00b3dbb8f618]

2008-11-04  Martin C. Frith  <Martin C. Frith>

	* src/LastalArguments.cc, src/LastdbArguments.cc:
	Added unistd.h includes, for getopt, so it compiles more portably(?)
	[fd6101b67cb2]

	* src/Centroid.cc, src/Centroid.hh, src/XdropAligner.cc,
	src/XdropAligner.hh, src/lastal.cc:
	Refactor: replaced a magic number with a named constant (score
	matrix size).
	[ffa2614e18f7]

2008-11-01  Martin C. Frith  <Martin C. Frith>

	* doc/last-scripts.txt, scripts/last-dotplot.py:
	Made last-dotplot.py work with older versions of Python (not
	tested).
	[0f2074e6853e]

2008-10-31  Martin C. Frith  <Martin C. Frith>

	* test/last-test.sh:
	Fixed the test script, which broke after moving HOXD70.
	[6e1ba8d97637]

	* doc/HOXD70, doc/last-manual.txt, examples/HOXD70,
	examples/fuguMito.fa, examples/humanMito.fa, examples/myalns.maf,
	makefile:
	Added the examples directory.
	[320185d87b4d]

2008-10-29  Martin C. Frith  <Martin C. Frith>

	* src/DiagonalTable.hh:
	Removed an obsolete comment.
	[42c5e4ccebcf]

	* src/DiagonalTable.hh:
	Made lastal a bit faster, by using fewer bins in DiagonalTable.
	[0d3bddb645db]

2008-10-25  Martin C. Frith  <Martin C. Frith>

	* src/Centroid.cc:
	Made the probability calculations slightly faster, by micro-
	optimization.
	[7c0912ff5085]

	* doc/last-manual.txt, src/Alignment.cc, src/Alignment.hh,
	src/Centroid.cc, src/Centroid.hh, src/lastal.cc:
	Made the probability calculations much faster, by using scaling
	instead of log.

	Added code to get expected counts of emissions and transitions,
	which isn't used yet.
	[c86b6d48881c]

2008-10-21  Martin C. Frith  <Martin C. Frith>

	* src/lastal.cc:
	Changed how seeds for gapped alignments are derived from gapless
	alignments, to prevent occasionally getting the same gapped
	alignment more than once.
	[59d3f3bb88b5]

2008-10-10  Martin C. Frith  <Martin C. Frith>

	* doc/last-manual.txt, src/CA_code/nrutil.c:
	Removed malloc.h from nrutil.c, so it compiles on Mac OS X. Small
	additions to the manual.
	[610626404a5f]

2008-10-02  Martin C. Frith  <Martin C. Frith>

	* doc/last-manual.txt, doc/last-scripts.txt, makefile,
	src/Alignment.cc, src/Alignment.hh, src/CA_code/lambda_calculator.c,
	src/CA_code/lambda_calculator.h, src/CA_code/lubksb.c,
	src/CA_code/ludcmp.c, src/CA_code/nrutil.c, src/CA_code/nrutil.h,
	src/Centroid.cc, src/Centroid.hh, src/LambdaCalculator.cc,
	src/LambdaCalculator.hh, src/LastalArguments.cc,
	src/LastalArguments.hh, src/XdropAligner.hh, src/lastal.cc,
	src/makefile, test/last-test.maf, test/last-test.sh:
	Added probabilistic & centroid alignment!
	[de5ce9b3bb54]

2008-10-01  Martin C. Frith  <Martin C. Frith>

	* scripts/last-remove-dominated.py, scripts/maf-swap.py:
	Made the MAF-reading scripts cope with an extra 'p' line
	(probabilities).
	[65a3cc262718]

2008-09-30  Martin C. Frith  <Martin C. Frith>

	* src/Alignment.cc, src/Alignment.hh:
	Minor comment changes.
	[cd714102b3a2]

	* doc/last-manual.txt, doc/tag-seeds.txt, src/LastalArguments.cc,
	src/LastdbArguments.cc, src/LastdbArguments.hh, test/last-test.maf:
	!! Changed the lastal option letter for "output type" from -g to -j
	(so that -g can be used for 'gamma' in gamma-centroid alignment).
	Made the usage messages and documentation a bit nicer.
	[1f6f2a03eb98]

	* doc/last-scripts.txt, scripts/maf-swap.py:
	Made maf-swap.py work with Python 2.3.3.
	[909d2ee4175a]

2008-09-18  Martin C. Frith  <Martin C. Frith>

	* src/AlignmentPot.hh, src/SegmentPairPot.hh, src/lastal.cc:
	Minor refactoring.
	[3dd1168849df]

	* src/XdropAligner.cc, src/XdropAligner.hh:
	Refactor: templatized some XdropAligner functions. This will be
	useful when probabilistic alignment gets added.
	[d801172578e3]

2008-09-17  Martin C. Frith  <Martin C. Frith>

	* src/Alignment.cc, src/XdropAligner.cc:
	Refactored the conversion of gapped Xdrop extensions to alignments.
	[1fedc2555ed5]

2008-09-16  Martin C. Frith  <Martin C. Frith>

	* doc/FAQ.txt:
	Added FAQ (just one entry so far).
	[58e83e93f3e0]

	* src/Alignment.cc, src/Alignment.hh, src/lastal.cc:
	Refactor: Made gapped alignments remember their seeds.
	[91e05856d155]

	* test/galGal3-M-32.fa, test/last-test.maf, test/last-test.sh:
	Added a minimal regression test.
	[aac5b622dcaa]

2008-09-11  Martin C. Frith  <Martin C. Frith>

	* src/Alignment.cc, src/AlignmentPot.hh, src/Alphabet.cc,
	src/MultiSequence.cc, src/PeriodicSpacedSeed.cc, src/ScoreMatrix.cc,
	src/ScoreMatrix.hh, src/SuffixArray.hh, src/XdropAligner.hh,
	src/lastal.cc, src/lastdb.cc:
	Added some "#include"s so that it compiles on picky systems.
	(Thanks: Charles Plessy)
	[cb9508f0bfa3]

2008-09-10  Martin C. Frith  <Martin C. Frith>

	* src/LastalArguments.cc:
	Added lastdbName to the header of the lastal output.
	[03416761788f]

	* src/lastdb.cc, src/makefile:
	Added version to lastdb ".prj" file.
	[36c3da67e3ac]

	* src/lastal.cc:
	Tiny change to the header in lastal output.
	[a598325bc0c3]

2008-09-09  Martin C. Frith  <Martin C. Frith>

	* doc/last-manual.txt:
	Added Harada-san to credits.
	[0a39bc158029]

2008-09-08  Martin C. Frith  <Martin C. Frith>

	* makefile:
	Separated "make dist" from "make all".
	[724a4bdb7734]

	* doc/last-manual.txt:
	Added Credits & Citation to last-manual.txt.
	[5125dcc2a9d8]

	* COPYING.txt, README.txt, doc/HOXD70, doc/evalue-tables.txt, doc
	/last-manual.txt, doc/last-scripts.txt, doc/tag-seeds.txt, makefile,
	scripts/last-dotplot.py, scripts/last-reduce-alignments.sh, scripts
	/last-remove-dominated.py, scripts/maf-sort.sh, scripts/maf-swap.py,
	scripts/maf2tab.py, src/Alignment.cc, src/Alignment.hh,
	src/AlignmentPot.cc, src/AlignmentPot.hh, src/Alphabet.cc,
	src/Alphabet.hh, src/DiagonalTable.cc, src/DiagonalTable.hh,
	src/GeneralizedAffineGapCosts.cc, src/GeneralizedAffineGapCosts.hh,
	src/LastalArguments.cc, src/LastalArguments.hh,
	src/LastdbArguments.cc, src/LastdbArguments.hh,
	src/MultiSequence.cc, src/MultiSequence.hh,
	src/PeriodicSpacedSeed.cc, src/PeriodicSpacedSeed.hh,
	src/ScoreMatrix.cc, src/ScoreMatrix.hh, src/SegmentPair.cc,
	src/SegmentPair.hh, src/SegmentPairPot.cc, src/SegmentPairPot.hh,
	src/SuffixArray.cc, src/SuffixArray.hh, src/XdropAligner.cc,
	src/XdropAligner.hh, src/io.cc, src/io.hh, src/lastal.cc,
	src/lastdb.cc, src/makefile, src/stringify.hh:
	First commit!
	[2b2012e60ac3]

2013-05-21  Martin C. Frith  <Martin C. Frith>

	* 0:
	Make Mercurial start counting from 1.
	[3f223f5d8e13]

